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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12455 scientific papers returned from the database with the search filters currently being used below.
There are 12455 scientific papers returned from the database with the search filters currently being used below.
Retinoic acid receptor (RAR) antagonists inhibit miR-10a expression and block metastatic behaviour of pancreatic cancer
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Citation:
Gastroenterology. 2009 Sep 9. [Epub ahead of print] Epub:
Not Epub Abstract:
BACKGROUND & AIMS:: The infiltrating ductal adenocarcinoma of the pancreas is among the most lethal of all solid... Organism or Cell Type:
cell culture: pancreatic carcinoma; zebrafish Citation Extract: Weiss FU, Marques IJ, Woltering JM, Vlecken DH, Aghdassi A, Partecke LI, Heidecke CD, Lerch MM, Bagowski CP. Retinoic acid receptor (RAR) antagonists inhibit miR-10a expression and block metastatic behaviour of pancreatic cancer. Gastroenterology. 2009 Sep 9. [Epub ahead of print]. |
Reversal of RNA dominance by displacement of protein sequestered on triplet repeat RNA
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Citation:
Science. 2009 Jul 17;325(5938):336-9 Epub:
Not Epub Abstract:
Genomic expansions of simple tandem repeats can give rise to toxic RNAs that contain expanded repeats. In myotonic dystrophy,... Delivery Method:
Injection then electroporation in mice, Endo-Porter in cultures Organism or Cell Type:
mice and cell culture: human DM1 fibroblasts Citation Extract: Wheeler TM, Sobczak K, Lueck JD, Osborne RJ, Lin X, Dirksen RT, Thornton CA. Reversal of RNA dominance by displacement of protein sequestered on triplet repeat RNA. Science. 2009 Jul 17;325(5938):336-9. |
Rho-regulated Myosin phosphatase establishes the level of protrusive activity required for cell movements during zebrafish gastrulation
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Citation:
Development. 2009 Jun 10. [Epub ahead of print] Epub:
Not Epub Abstract:
Rho-dependent amoeboid cell movement is a crucial mechanism in both tumor cell invasion and morphogenetic cell movements during... Delivery Method:
Microinjection of embryo, then cell transplantation Organism or Cell Type:
zebrafish Citation Extract: Weiser DC, Row RH, Kimelman D. Rho-regulated Myosin phosphatase establishes the level of protrusive activity required for cell movements during zebrafish gastrulation. Development. 2009 Jun 10. [Epub ahead of print]. |
RNA Splicing Manipulation: Strategies to Modify Gene Expression for a Variety of Therapeutic Outcomes
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Citation:
Curr Gene Ther. 2011 Apr 1. [Epub ahead of print] Epub:
Not Epub Abstract:
Antisense oligomers initially showed promise as compounds to modify gene expression, primarily through RNaseH induced... Citation Extract: Wilton SD, Fletcher S. RNA Splicing Manipulation: Strategies to Modify Gene Expression for a Variety of Therapeutic Outcomes. Curr Gene Ther. 2011 Apr 1. [Epub ahead of print]. |
Role of SLC12A10.2, a Na-Cl cotransporter-like protein, in a Cl uptake mechanism in zebrafish (Danio rerio)
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Citation:
Am J Physiol Regul Integr Comp Physiol. 2009 Mar 11. [Epub ahead of print] Epub:
Not Epub Abstract:
The thiazide-sensitive Na(+)-Cl(-) cotransporter (NCC), a member of the SLC12 family, is mainly expressed in the apical... Organism or Cell Type:
zebrafish Citation Extract: Wang YF, Tseng YC, Yan JJ, Hiroi J, Hwang PP. Role of SLC12A10.2, a Na-Cl cotransporter-like protein, in a Cl uptake mechanism in zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2009 Mar 11. [Epub ahead of print]. |
Roles of ADAM13-regulated Wnt activity in early Xenopus eye development
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Citation:
Dev Biol. 2011 Dec 28. [Epub ahead of print] Epub:
Not Epub Abstract:
Pericellular proteolysis by ADAM family metalloproteinases has been widely implicated in cell signaling and development. We... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Wei S, Xu G, Bridges LC, Williams P, Nakayama T, Shah A, Grainger RM, White JM, Desimone DW. Roles of ADAM13-regulated Wnt activity in early Xenopus eye development. Dev Biol. 2011 Dec 28. [Epub ahead of print]. |
Semaphorin3D regulates axon axon interactions by modulating levels of L1 cell adhesion molecule
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Citation:
J Neurosci. 2007 Sep 5;27(36):9653-63 Epub:
Not Epub Abstract:
The decision of a growing axon to selectively fasciculate with and defasciculate from other axons is critical for axon... Organism or Cell Type:
zebrafish Citation Extract: Wolman MA, Regnery AM, Becker T, Becker CG, Halloran MC. Semaphorin3D regulates axon axon interactions by modulating levels of L1 cell adhesion molecule. J Neurosci. 2007 Sep 5;27(36):9653-63. |
Sequence Specificity of Alternating Hydroyprolyl/phosphono Peptide Nucleic Acids against Zebrafish Embryo mRNAs
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Citation:
J Drug Target. 2004 Jul;12(6):363-72 Epub:
Not Epub Abstract:
Morpholino phosphorodiamidate (MO) DNA mimics display excellent water solubility and hybridization properties toward DNA and... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Wickstrom E, Choob M, Urtishak KA, Tian X, Sternheim N, Talbot S, Archdeacon J, Efimov VA, Farber SA. Sequence Specificity of Alternating Hydroyprolyl/phosphono Peptide Nucleic Acids against Zebrafish Embryo mRNAs. J Drug Target. 2004 Jul;12(6):363-72. |
Simplified Preparation via Streptavidin of Antisense Oligomers/Carriers Nanoparticles Showing Improved Cellular Delivery in Culture
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Citation:
Bioconjug Chem. 2007 Jul-Aug;18(4):1338-43. Epub 2007 Jul 3. Epub:
Not Epub Abstract:
Objective: Carriers are increasingly now viewed as helpful or even essential to improve cellular uptake in connection with... Delivery Method:
Nanoparticle Citation Extract: Wang Y, Nakamura K, Liu X, Kitamura N, Kubo A, Hnatowich DJ. Simplified Preparation via Streptavidin of Antisense Oligomers/Carriers Nanoparticles Showing Improved Cellular Delivery in Culture. Bioconjug Chem. 2007 Jul-Aug;18(4):1338-43. Epub 2007 Jul 3.. |
SIX2 and BMP4 Mutations Associate With Anomalous Kidney Development
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Citation:
J Am Soc Nephrol. 2008 May;19(5):891-903. Epub 2008 Feb 27. Epub:
Not Epub Abstract:
Renal hypodysplasia (RHD) is characterized by reduced kidney size and/or maldevelopment of the renal tissue following abnormal... Organism or Cell Type:
zebrafish Citation Extract: Weber S, Taylor JC, Winyard P, Baker KF, Sullivan-Brown J, Schild R, Knüppel T, Zurowska AM, Caldas-Alfonso A, Litwin M, Emre S, Ghiggeri GM, Bakkaloglu A, Mehls O, Antignac C; Escape Network, Schaefer F, Burdine RD. SIX2 and BMP4 Mutations Associate With Anomalous Kidney Development. J Am Soc Nephrol. 2008 May;19(5):891-903. Epub 2008 Feb 27.. |