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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Dopachrome tautomerase variants in patients with oculocutaneous albinism

Authors:
Pennamen P, Tingaud-Sequeira A, Gazova I, Keighren M, McKie L, Marlin S, Gherbi Halem S, Kaplan J, Delevoye C, Lacombe D, Plaisant C, Michaud V, Lasseaux E, Javerzat S, Jackson I, Arveiler B
Citation:
Genet Med. 2020 Oct 26. doi: 10.1038/s41436-020-00997-8. Online ahead of print
Epub:
Yes
Abstract:
Purpose: Albinism is a clinically and genetically heterogeneous condition. Despite analysis of the 20 known genes, ~30%...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pennamen P, Tingaud-Sequeira A, Gazova I, Keighren M, McKie L, Marlin S, Gherbi Halem S, Kaplan J, Delevoye C, Lacombe D, Plaisant C, Michaud V, Lasseaux E, Javerzat S, Jackson I, Arveiler B. Dopachrome tautomerase variants in patients with oculocutaneous albinism. Genet Med. 2020 Oct 26. doi: 10.1038/s41436-020-00997-8. Online ahead of print.

E-cadherin focuses protrusion formation at the front of migrating cells by impeding actin flow

Authors:
Grimaldi C, Schumacher I, Boquet-Pujadas A, Tarbashevich K, Vos BE, Bandemer J, Schick J, Aalto A, Olivo-Marin JC, Betz T, Raz E
Citation:
Nat Commun. 2020 Oct 26;11(1):5397. doi: 10.1038/s41467-020-19114-z
Epub:
Not Epub
Abstract:
The migration of many cell types relies on the formation of actomyosin-dependent protrusions called blebs, but the mechanisms...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Grimaldi C, Schumacher I, Boquet-Pujadas A, Tarbashevich K, Vos BE, Bandemer J, Schick J, Aalto A, Olivo-Marin JC, Betz T, Raz E. E-cadherin focuses protrusion formation at the front of migrating cells by impeding actin flow. Nat Commun. 2020 Oct 26;11(1):5397. doi: 10.1038/s41467-020-19114-z.

The cationic amino acid exporter Slc7a7 is induced and vital in zebrafish tissue macrophages with sustained efferocytic activity

Authors:
Demy DL, Carrère M, Noche R, Tauzin M, Le Bris M, Baek C, Leshchiner I, Goessling W, Herbomel P
Citation:
J Cell Sci. 2020 Oct 22;133(20):jcs249037. doi: 10.1242/jcs.249037
Epub:
Not Epub
Abstract:
Most tissues harbor a substantial population of resident macrophages. Here, we elucidate a functional link between the Slc7a7...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Demy DL, Carrère M, Noche R, Tauzin M, Le Bris M, Baek C, Leshchiner I, Goessling W, Herbomel P. The cationic amino acid exporter Slc7a7 is induced and vital in zebrafish tissue macrophages with sustained efferocytic activity. J Cell Sci. 2020 Oct 22;133(20):jcs249037. doi: 10.1242/jcs.249037.

Robust Filtering and Noise Suppression in Intragenic miRNA-Mediated Host Regulation

Authors:
Kang T, Quarton T, Nowak CM, Ehrhardt K, Singh A, Li Y, Bleris L
Citation:
iScience. 2020 Sep 21;23(10):101595. doi: 10.1016/j.isci.2020.101595. eCollection 2020 Oct 23
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are short non-coding RNA molecules that regulate gene expression post-transcriptionally by binding to target...
Organism or Cell Type:
cell culture: HEK293
Citation Extract:
Kang T, Quarton T, Nowak CM, Ehrhardt K, Singh A, Li Y, Bleris L. Robust Filtering and Noise Suppression in Intragenic miRNA-Mediated Host Regulation. iScience. 2020 Sep 21;23(10):101595. doi: 10.1016/j.isci.2020.101595. eCollection 2020 Oct 23.

Identification of novel susceptibility loci for non-syndromic cleft lip with or without cleft palate

Authors:
Ma L, Lou S, Miao Z, Yao S, Yu X, Kan S, Zhu G, Yang F, Zhang C, Zhang W, Wang M, Wang L, Pan Y
Citation:
J Cell Mol Med. 2020 Oct 27. doi: 10.1111/jcmm.15878. Online ahead of print
Epub:
Yes
Abstract:
Although several genome-wide association studies (GWAS) of non-syndromic cleft lip with or without cleft palate (NSCL/P) have...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ma L, Lou S, Miao Z, Yao S, Yu X, Kan S, Zhu G, Yang F, Zhang C, Zhang W, Wang M, Wang L, Pan Y. Identification of novel susceptibility loci for non-syndromic cleft lip with or without cleft palate. J Cell Mol Med. 2020 Oct 27. doi: 10.1111/jcmm.15878. Online ahead of print.

X-box-binding protein 1 is required for pancreatic development in Xenopus laevis

Authors:
Yang J, Liu X, Yuan F, Liu J, Li D, Wei L, Wang X, Yuan L
Citation:
Acta Biochim Biophys Sin (Shanghai). 2020 Oct 24:gmaa114. doi: 10.1093/abbs/gmaa114. Online ahead of print
Epub:
Yes
Abstract:
X-box-binding protein 1 (XBP1) is a protein containing the basic leucine zipper structure. It belongs to the cAMP-response...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yang J, Liu X, Yuan F, Liu J, Li D, Wei L, Wang X, Yuan L. X-box-binding protein 1 is required for pancreatic development in Xenopus laevis. Acta Biochim Biophys Sin (Shanghai). 2020 Oct 24:gmaa114. doi: 10.1093/abbs/gmaa114. Online ahead of print.

Use of a carbonic anhydrase ca17a knockout to investigate mechanisms of ion uptake in zebrafish (Danio rerio)

Authors:
Zimmer AM, Mandic M, Yew HM, Kunert E, Pan YK, Ha J, Kwong RWM, Gilmour KM, Perry SF
Citation:
Am J Physiol Regul Integr Comp Physiol. 2020 Oct 21. doi: 10.1152/ajpregu.00215.2020. Online ahead of print
Epub:
Yes
Abstract:
In fishes, branchial cytosolic carbonic anhydrase (CA) plays an important role in ion and acid-base regulation. The Ca17a...
Organism or Cell Type:
zebrafish
Citation Extract:
Zimmer AM, Mandic M, Yew HM, Kunert E, Pan YK, Ha J, Kwong RWM, Gilmour KM, Perry SF. Use of a carbonic anhydrase ca17a knockout to investigate mechanisms of ion uptake in zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2020 Oct 21. doi: 10.1152/ajpregu.00215.2020. Online ahead of print.

Aconitine disrupts serotonin neurotransmission via 5-hydroxytryptamine receptor in zebrafish embryo

Authors:
Chen H, Wang F, Ni X, Rigui Y, Bai Y, Xu L, Yang J, Zhang X, Deng J, Li J, Yin X, Ao W, Kwok KWH, Dong W
Citation:
J Appl Toxicol. 2020 Oct 21. doi: 10.1002/jat.4059. Online ahead of print
Epub:
Not Epub
Abstract:
Medicinal plants of the genus Aconitum are one of the most commonly used herbs in traditional medicine in East Asia to treat...
Organism or Cell Type:
zebrafish
Citation Extract:
Chen H, Wang F, Ni X, Rigui Y, Bai Y, Xu L, Yang J, Zhang X, Deng J, Li J, Yin X, Ao W, Kwok KWH, Dong W. Aconitine disrupts serotonin neurotransmission via 5-hydroxytryptamine receptor in zebrafish embryo. J Appl Toxicol. 2020 Oct 21. doi: 10.1002/jat.4059. Online ahead of print.

A novel Golgi-associated Vangl2 translational variant required for PCP regulation in vertebrates

Authors:
Walton A, Revinski D, Serge A, Audebert S, Camoin L, Puvirajesinghe TM, Isnardon D, Marchetto S, Kodjabachian L, Bailly E, Borg J-P
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.10.20.347385
Epub:
Not Epub
Abstract:
First described in Drosophila melanogaster, planar cell polarity (PCP) is a developmental process essential for embryogenesis...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Walton A, Revinski D, Serge A, Audebert S, Camoin L, Puvirajesinghe TM, Isnardon D, Marchetto S, Kodjabachian L, Bailly E, Borg J-P. A novel Golgi-associated Vangl2 translational variant required for PCP regulation in vertebrates. bioRxiv. 2020;[preprint] doi:10.1101/2020.10.20.347385 .

Effect of Mutated ids Overexpression on IDS Enzyme Activity and Developmental Phenotypes in Zebrafish Embryos: A Valuable Index for Assessing Critical Point-Mutations Associated with Mucopolysaccharidosis Type II Occurrence in Humans

Authors:
Lin C-Y, Lin H-Y, Chuang C-K, Zhang P-H, Tu 4 R-Y, Lin S-P, Tsai H-J
Citation:
Diagnostics. 2020;10(10):854 doi:10.3390/diagnostics10100854
Epub:
Not Epub
Abstract:
Mucopolysaccharidosis type II (MPS II) is an X-linked disorder resulting from a deficiency in iduronate 2-sulfatase (IDS),...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin C-Y, Lin H-Y, Chuang C-K, Zhang P-H, Tu 4 R-Y, Lin S-P, Tsai H-J. Effect of Mutated ids Overexpression on IDS Enzyme Activity and Developmental Phenotypes in Zebrafish Embryos: A Valuable Index for Assessing Critical Point-Mutations Associated with Mucopolysaccharidosis Type II Occurrence in Humans. Diagnostics. 2020;10(10):854 doi:10.3390/diagnostics10100854.

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