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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

delta-Np63-alpha Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis

Authors:
Keyes WM, Pecoraro M, Aranda V, Vernersson-Lindahl E, Li W, Vogel H, Guo X, Garcia EL, Michurina TV, Enikolopov G, Muthuswamy SK, Mills AA
Citation:
Cell stem cell. 2011;8(2):164-76 doi:10.1016/j.stem.2010.12.009
Epub:
Not Epub
Abstract:
The p53 homolog p63 is essential for development, yet its role in cancer is not clear. We discovered that p63 deficiency evokes...
Citation Extract:
Keyes WM, Pecoraro M, Aranda V, Vernersson-Lindahl E, Li W, Vogel H, Guo X, Garcia EL, Michurina TV, Enikolopov G, Muthuswamy SK, Mills AA. delta-Np63-alpha Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis. Cell stem cell. 2011;8(2):164-76 doi:10.1016/j.stem.2010.12.009.

Depletion of three BMP antagonists from Spemann's organizer leads to a catastrophic loss of dorsal structures

Authors:
Khokha MK, Yeh J, Grammer TC, Harland RM
Citation:
Dev Cell. 2005 Mar;8(3):401-11
Epub:
Not Epub
Abstract:
Transplanted Spemann's organizer induces dorsal embryonic cell fates such as the nervous system and somites, but in normal...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Khokha MK, Yeh J, Grammer TC, Harland RM. Depletion of three BMP antagonists from Spemann's organizer leads to a catastrophic loss of dorsal structures. Dev Cell. 2005 Mar;8(3):401-11.

ENU-induced Mutation in the DNA-binding Domain of KLF3 Reveals Important Roles for KLF3 in Cardiovascular Development and Function in Mice

Authors:
Kelsey L, Flenniken AM, Qu D, Funnell APW, Pearson R, Zhou Y-Q, Voronina I, Berberovic Z, Wood G, Newbigging S, Weiss ES, Wong M, Quach I, Yeh SY, Deshwar AR, Scott IC, McKerlie C, Henkelman M, Backx P, Simpson J, Osborne L, Rossant J, Crossley M, Bruneau B, Adamson SL
Citation:
PLoS Genet. 2013;9(7):e1003612. doi:10.1371/journal.pgen.1003612
Epub:
Not Epub
Abstract:
KLF3 is a Krüppel family zinc finger transcription factor with widespread tissue expression and no previously known role in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kelsey L, Flenniken AM, Qu D, Funnell APW, Pearson R, Zhou Y-Q, Voronina I, Berberovic Z, Wood G, Newbigging S, Weiss ES, Wong M, Quach I, Yeh SY, Deshwar AR, Scott IC, McKerlie C, Henkelman M, Backx P, Simpson J, Osborne L, Rossant J, Crossley M, Bruneau B, Adamson SL. ENU-induced Mutation in the DNA-binding Domain of KLF3 Reveals Important Roles for KLF3 in Cardiovascular Development and Function in Mice. PLoS Genet. 2013;9(7):e1003612. doi:10.1371/journal.pgen.1003612.

EphA4 and EfnB2a maintain rhombomere coherence by independently regulating intercalation of progenitor cells in the zebrafish neural keel

Authors:
Kemp HA, Cooke JE, Moens CB
Citation:
Dev Biol. 2009 Mar 15;327(2):313-26. Epub 2008 Dec 24
Epub:
Not Epub
Abstract:
During vertebrate development, the hindbrain is transiently segmented into 7 distinct rhombomeres (r). Hindbrain segmentation...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kemp HA, Cooke JE, Moens CB. EphA4 and EfnB2a maintain rhombomere coherence by independently regulating intercalation of progenitor cells in the zebrafish neural keel. Dev Biol. 2009 Mar 15;327(2):313-26. Epub 2008 Dec 24.

Essential role for beta-arrestin 2 in the regulation of Xenopus convergent extension movements

Authors:
Kim GH, Han JK
Citation:
EMBO J. 2007 May 16;26(10):2513-26. Epub 2007 May 3
Epub:
Not Epub
Abstract:
beta-Arrestin 2 (betaarr2) is a multifunctional protein that regulates numerous aspects of G-protein-coupled receptor function...
Organism or Cell Type:
Xenopus
Citation Extract:
Kim GH, Han JK. Essential role for beta-arrestin 2 in the regulation of Xenopus convergent extension movements. EMBO J. 2007 May 16;26(10):2513-26. Epub 2007 May 3.

gbx2 Homeobox gene is required for the maintenance of the isthmic region in the zebrafish embryonic brain

Authors:
Kikuta H, Kanai M, Ito Y, Yamasu K
Citation:
Dev Dyn. 2003 Nov;228(3):433-50
Epub:
Not Epub
Abstract:
We isolated cDNA clones for the zebrafish gbx2 gene, which is implicated in the establishment of the midbrain-hindbrain...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kikuta H, Kanai M, Ito Y, Yamasu K. gbx2 Homeobox gene is required for the maintenance of the isthmic region in the zebrafish embryonic brain. Dev Dyn. 2003 Nov;228(3):433-50.

Geminin Is Required for Zygotic Gene Expression at the Xenopus Mid-Blastula Transition

Authors:
Kerns SL, Schultz KM, Barry KA, Thorne TM, McGarry TJ
Citation:
PLoS ONE. 2012;7(5): e38009. doi:10.1371/journal.pone.0038009
Epub:
Not Epub
Abstract:
In many organisms early development is under control of the maternal genome and zygotic gene expression is delayed until the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kerns SL, Schultz KM, Barry KA, Thorne TM, McGarry TJ. Geminin Is Required for Zygotic Gene Expression at the Xenopus Mid-Blastula Transition. PLoS ONE. 2012;7(5): e38009. doi:10.1371/journal.pone.0038009.

HtrA1 is a novel antagonist controlling fibroblast growth factor (FGF) signaling via cleavage of FGF8

Authors:
Kim GY, Kim HY, Kim HT, Moon JM, Kim CH, Kang S, Rhim H
Citation:
Mol Cell Biol. 2012 Nov;32(21):4482-92. doi: 10.1128/MCB.00872-12. Epub 2012 Sep 4
Epub:
Not Epub
Abstract:
Accumulating evidence suggests that HtrA1 (high-temperature requirement A1) is involved in modulating crucial cellular...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim GY, Kim HY, Kim HT, Moon JM, Kim CH, Kang S, Rhim H. HtrA1 is a novel antagonist controlling fibroblast growth factor (FGF) signaling via cleavage of FGF8. Mol Cell Biol. 2012 Nov;32(21):4482-92. doi: 10.1128/MCB.00872-12. Epub 2012 Sep 4.

Lens and retina formation require expression of Pitx3 in Xenopus pre-lens ectoderm

Authors:
Khosrowshahian F, Wolanski M, Chang WY, Fujiki K, Jacobs L, Crawford MJ
Citation:
Dev Dyn. 2005 Nov;234(3):577-89.
Epub:
Not Epub
Abstract:
Pitx3 is expressed in tissues fated to contribute to eye development, namely, neurula stage ectoderm and prechordal mesoderm,...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Khosrowshahian F, Wolanski M, Chang WY, Fujiki K, Jacobs L, Crawford MJ. Lens and retina formation require expression of Pitx3 in Xenopus pre-lens ectoderm. Dev Dyn. 2005 Nov;234(3):577-89..

M-Ras evolved independently of R-Ras and its neural function is conserved between mammalian and ascidian, which lacks classical Ras

Authors:
Keduka E, Kaiho A, Hamada M, Watanabe-Takano H, Takano K, Ogasawara M, Satou Y, Satoh N, Endo T
Citation:
Gene. 2009 Jan 15;429(1-2):49-58. doi: 10.1016/j.gene.2008.10.001. Epub 2008 Oct 11.
Epub:
Not Epub
Abstract:
The Ras family small GTPases play a variety of essential roles in eukaryotes. Among them, classical Ras (H-Ras, K-Ras, and N-...
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Keduka E, Kaiho A, Hamada M, Watanabe-Takano H, Takano K, Ogasawara M, Satou Y, Satoh N, Endo T. M-Ras evolved independently of R-Ras and its neural function is conserved between mammalian and ascidian, which lacks classical Ras. Gene. 2009 Jan 15;429(1-2):49-58. doi: 10.1016/j.gene.2008.10.001. Epub 2008 Oct 11..

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