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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Rspo2 inhibits TCF3 phosphorylation to antagonize Wnt signaling during vertebrate anteroposterior axis specification
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Citation:
bioRxiv. 2020;[preprint] doi:/10.1101/2020.10.30.362541 Epub:
Not Epub Abstract:
The Wnt pathway activates target genes by controlling the b-catenin-T-cell factor (TCF) transcriptional complex during... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Reis AH, Sokol SY. Rspo2 inhibits TCF3 phosphorylation to antagonize Wnt signaling during vertebrate anteroposterior axis specification. bioRxiv. 2020;[preprint] doi:/10.1101/2020.10.30.362541 . |
Uncovering the mesendoderm gene regulatory network through multi-omic data integration
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.01.362053 Epub:
Not Epub Abstract:
Mesendodermal specification is one of the earliest events in embryogenesis, where cells first acquire distinct identities. Cell... Organism or Cell Type:
Xenopus Citation Extract: Jansen C, Paraiso K, Zhou J, Blitz IL, Fish M, Charney R, Cho JS, Yasuoka Y, Sudou N, Bright AR, Wlizla M, Veenstra GJC, Taira M, Zorn A, Mortazavi A, Cho KWY. Uncovering the mesendoderm gene regulatory network through multi-omic data integration. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.01.362053. |
Prostasin and hepatocyte growth factor B in factor VIIa generation: Serine protease knockdowns in zebrafish
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Citation:
Res Pract Thromb Haemost. 2020 Sep 22;4(7):1150-1157. doi: 10.1002/rth2.12428. eCollection 2020 Oct Epub:
Not Epub Abstract:
Background: Blood clotting in humans is initiated by the binding of tissue factor to activated coagulation factor VII (FVIIa)... Delivery Method:
Vivo-Morpholino (piggyback) Organism or Cell Type:
zebrafish Citation Extract: Khandekar G, Iyer N, Jagadeeswaran P. Prostasin and hepatocyte growth factor B in factor VIIa generation: Serine protease knockdowns in zebrafish. Res Pract Thromb Haemost. 2020 Sep 22;4(7):1150-1157. doi: 10.1002/rth2.12428. eCollection 2020 Oct. |
Influence of astrocytic glutamine transporter SN1 deficiency on electrophysiological correlates of glutamatergic transmission
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Citation:
J Neurochem. 2017; 142(suppl 1):125. doi:10.1111/jnc.14093 Epub:
Not Epub Abstract:
The N-system glutamine transporter SN1 preferentially transfers glutamine out of astrocytes (Chaudhry et al., Cell 1999), and... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Popek M, Bobula B, Sowa J, Hess G, Albrecht J, Zielinska M. Influence of astrocytic glutamine transporter SN1 deficiency on electrophysiological correlates of glutamatergic transmission. J Neurochem. 2017; 142(suppl 1):125. doi:10.1111/jnc.14093. |
Phosphatidylinositol 4 kinase-β mutations cause non-syndromic sensorineural deafness and inner ear malformation
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Citation:
J Genet Genom. 2020;[Epub] doi:10.1016/j.jgg.2020.07.008 Epub:
Yes Abstract:
Congenital hearing loss is a common disorder worldwide. Heterogeneous gene variation accounts for approximately 20% - 25% of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Su X, Feng Y, Rahman SA, Wu S, Li G, Rüschendorf F, Zhao L, Cui H, Liang J, Fang L, Hu H, Froehler S, Yu Y, Patone G, Hummel O, Chen Q, Raile K, Luft FC, Bähring S, Hussain K, Chen W, Zhang J, Gong. Phosphatidylinositol 4 kinase-β mutations cause non-syndromic sensorineural deafness and inner ear malformation. J Genet Genom. 2020;[Epub] doi:10.1016/j.jgg.2020.07.008. |
Fibulin 5, a human Wharton's jelly-derived mesenchymal stem cells-secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin-RAC1 signaling axis
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Citation:
Stem Cells. 2020 Oct 27. doi: 10.1002/stem.3287. Online ahead of print Epub:
Yes Abstract:
In the peripheral nervous system (PNS), proper development of Schwann cells (SCs) contributing to axonal myelination is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Won SY, Kwon S, Jeong HS, Chung KW, Choi BO, Chang JW, Lee JE. Fibulin 5, a human Wharton's jelly-derived mesenchymal stem cells-secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin-RAC1 signaling axis. Stem Cells. 2020 Oct 27. doi: 10.1002/stem.3287. Online ahead of print. |
Sox2 and Canonical Wnt Signaling Interact to Activate a Developmental Checkpoint Coordinating Morphogenesis with Mesoderm Fate Acquisition
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Citation:
Cell Rep. 2020;33(4):108311. doi:10.1016/j.celrep.2020.108311 Epub:
Not Epub Abstract:
Animal embryogenesis requires a precise coordination between morphogenesis and cell fate specification. During mesoderm... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kinney BA, Anber AA, Row RH, Tseng Y-J, Weidmann MD, Knaut H, Martin BL. Sox2 and Canonical Wnt Signaling Interact to Activate a Developmental Checkpoint Coordinating Morphogenesis with Mesoderm Fate Acquisition. Cell Rep. 2020;33(4):108311. doi:10.1016/j.celrep.2020.108311. |
GNAO1 organizes the cytoskeletal remodeling and firing of developing neurons
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Citation:
FASEB J. 2020 Oct 27;[Epub ahead of print] doi:10.1096/fj.202001113R. Online ahead of print Epub:
Yes Abstract:
Developmental and epileptic encephalopathy (DEE) represents a group of neurodevelopmental disorders characterized by infantile‐... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Akamine S, Okuzono S, Yamamoto H, Setoyama D, Sagata N, Ohgidani M, Kato TA, Ishitani T, Kato H, Masuda K, Matsushita Y, Ono H, Ishizaki Y, Sanefuji M, Saitsu H, Matsumoto N, Kang D, Kanba S, Nakabeppu Y, Sakai Y, Ohga S. GNAO1 organizes the cytoskeletal remodeling and firing of developing neurons. FASEB J. 2020 Oct 27;[Epub ahead of print] doi:10.1096/fj.202001113R. Online ahead of print. |
Actin-based protrusions lead microtubules during stereotyped axon initiation in spinal neurons in vivo
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.10.24.353284 Epub:
Not Epub Abstract:
In vitro, developing neurons progress through well-defined stages to form an axon and multiple dendrites. In vivo, neurons are... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Moore RE, Pop S, Alleyne C, Clarke JDW. Actin-based protrusions lead microtubules during stereotyped axon initiation in spinal neurons in vivo. bioRxiv. 2020;[preprint] doi:10.1101/2020.10.24.353284 . |
Dual function of perivascular fibroblasts in vascular stabilization in zebrafish
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Citation:
PLoS Genet. 2020;16(10):e1008800. doi:10.1371/journal.pgen.1008800 Epub:
Not Epub Abstract:
Blood vessels are vital to sustain life in all vertebrates. While it is known that mural cells (pericytes and smooth muscle... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rajan AM, Ma RC, Kocha KM, Zhang DJ, Huang P. Dual function of perivascular fibroblasts in vascular stabilization in zebrafish. PLoS Genet. 2020;16(10):e1008800. doi:10.1371/journal.pgen.1008800. |