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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Aryl hydrocarbon receptor mediates larval zebrafish fin duplication following exposure to benzofluoranthenes
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Citation:
Toxicol Sci. 2020 May 8. pii: kfaa063. doi: 10.1093/toxsci/kfaa063. [Epub ahead of print] Epub:
Yes Abstract:
The aryl hydrocarbon receptor (AHR) mediates developmental toxicity of several xenobiotic classes including polycyclic aromatic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Garland MA, Geier MC, Bugel SM, Shankar P, Dunham CL, Brown JM, Tilton SC, Tanguay RL. Aryl hydrocarbon receptor mediates larval zebrafish fin duplication following exposure to benzofluoranthenes. Toxicol Sci. 2020 May 8. pii: kfaa063. doi: 10.1093/toxsci/kfaa063. [Epub ahead of print]. |
Uncoupling Splicing From Transcription Using Antisense Oligonucleotides Reveals a Dual Role for I Exon Donor Splice Sites in Antibody Class Switching
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Citation:
Front Immunol. 2020;11:780. doi:10.3389/fimmu.2020.00780 Epub:
Not Epub Abstract:
Class switch recombination (CSR) changes antibody isotype by replacing Cμ constant exons with different constant exons located... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: murine splenic B cells Citation Extract: Marchalot A, Ashi MO, Lambert JM, Carrion C, Lecardeur S, Srour N, Delpy L, Le Pennec S. Uncoupling Splicing From Transcription Using Antisense Oligonucleotides Reveals a Dual Role for I Exon Donor Splice Sites in Antibody Class Switching. Front Immunol. 2020;11:780. doi:10.3389/fimmu.2020.00780. |
Composition-dependent thermodynamics of intracellular phase separation
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Citation:
Nature. 2020;[Epub]. doi:10.1038/s41586-020-2256-2 Epub:
Yes Abstract:
Intracellular bodies such as nucleoli, Cajal bodies and various signalling assemblies represent membraneless organelles, or... Citation Extract: Riback JA, Zhu L, Ferrolino MC, Tolbert M, Mitrea DM, Sanders DW, Wei M-T, Kriwacki RW, Brangwynne CP. Composition-dependent thermodynamics of intracellular phase separation. Nature. 2020;[Epub]. doi:10.1038/s41586-020-2256-2. |
Knocking-down of the Prokineticin receptor 2 affects reveals its complex role in the regulation of the hypothalamus-pituitary-gonadal axis in the zebrafish model
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Citation:
Sci Rep. 2020;10(1):7632 doi:10.1038/s41598-020-64077-2 Epub:
Not Epub Abstract:
Prokineticin receptors (PROKR1 and PROKR2) are G protein-coupled receptors which control human central and peripheral... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bassi I, Luzzani F, Marelli F, Vezzoli V, Cotellessa L, Prober DA, Persani L, Gothilf Y, Bonomi M. Knocking-down of the Prokineticin receptor 2 affects reveals its complex role in the regulation of the hypothalamus-pituitary-gonadal axis in the zebrafish model. Sci Rep. 2020;10(1):7632 doi:10.1038/s41598-020-64077-2. |
Activating transcription factor 3 coordinates differentiation of cardiac and hematopoietic progenitors by regulating glucose metabolism
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Citation:
Sci Adv. 2020;6(19):eaay9466 doi:10.1126/sciadv.aay9466 Epub:
Not Epub Abstract:
The cardiac and hematopoietic progenitors (CPs and HPs, respectively) in the mesoderm ultimately form a well-organized... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yin H-M, Yan L-F, Liu Q, Peng Z, Zhang C-Y, Xia Y, Su D, Gu A-H, Zhou Y. Activating transcription factor 3 coordinates differentiation of cardiac and hematopoietic progenitors by regulating glucose metabolism. Sci Adv. 2020;6(19):eaay9466 doi:10.1126/sciadv.aay9466. |
The Rho guanine nucleotide exchange factor Trio is required for neural crest cell migration and interacts with Dishevelled
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Citation:
Development. 2020 May 4. pii: dev.186338. doi: 10.1242/dev.186338. [Epub ahead of print] Epub:
Yes Abstract:
Directional migration during embryogenesis and tumor progression faces the challenge that numerous external signals need to... Organism or Cell Type:
Xenopus Citation Extract: Kratzer MC, Becker SFS, Grund A, Merks A, Harnoš J, Bryja V, Giehl K, Kashef J, Borchers A. The Rho guanine nucleotide exchange factor Trio is required for neural crest cell migration and interacts with Dishevelled. Development. 2020 May 4. pii: dev.186338. doi: 10.1242/dev.186338. [Epub ahead of print]. |
Pcgf1 regulates early neural tube development through histone methylation in zebrafish
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Citation:
Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-25978/v1 Epub:
Not Epub Abstract:
Objective: Early neural tube development in the embryo includes neural induction and self-renewal of neural stem cells (NSCs).... Organism or Cell Type:
zebrafish Citation Extract: Li X, Ji G, Zhou J, Du J, Li X, Hu Y, Zhou W, Hao A. Pcgf1 regulates early neural tube development through histone methylation in zebrafish. Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-25978/v1. |
Rspo2 antagonizes FGF signaling during vertebrate mesoderm formation and patterning
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Citation:
Development. 2020;[Epub ahead of print] dev.189324 doi: 10.1242/dev.189324 Epub:
Yes Abstract:
R-spondins are a family of secreted proteins that play important roles in embryonic development and cancer. R-spondins have... Organism or Cell Type:
Xenopus Citation Extract: Reis AH, Sokol SY. Rspo2 antagonizes FGF signaling during vertebrate mesoderm formation and patterning. Development. 2020;[Epub ahead of print] dev.189324 doi: 10.1242/dev.189324. |
Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing
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Citation:
J Am Chem Soc. 2020;[Epub ahead of print] doi:10.1021/jacs.0c00768 Epub:
Yes Abstract:
Approximately 95% of human genes are alternatively spliced, and aberrant splicing events can cause disease. One pre-mRNA that... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: HeLa Citation Extract: Chen JL, Zhang P, Abe M, Aikawa H, Zhang L, Frank AJ, Zembryski T, Hubbs C, Park HJ, Withka J, Steppan C, Rogers L, Cabral S, Pettersson M, Wager TT, Fountain MA, Rumbaugh G, Childs-Disney JL, Disney MD. Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. J Am Chem Soc. 2020;[Epub ahead of print] doi:10.1021/jacs.0c00768. |
Myogenesis modelled by human pluripotent stem cells uncovers Duchenne muscular dystrophy phenotypes prior to skeletal muscle commitment
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/720920 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) causes severe disability of children and death of young men, with an incidence of... Delivery Method:
electroporation Organism or Cell Type:
cell culture: M180 Citation Extract: Mournetas V, Massouridès E, Dupont J-B, Kornobis E, Polvèche H, Jarrige M, Gosselin MRF, Manousopoulou A, Garbis SD, Górecki DC, Pinset C. Myogenesis modelled by human pluripotent stem cells uncovers Duchenne muscular dystrophy phenotypes prior to skeletal muscle commitment. bioRxiv. 2020;[preprint] doi:10.1101/720920 . |