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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Circulating factors cause proteinuria in parabiotic zebrafish

Authors:
Müller-Deile J, Schenk H, Schroder P, Schulze K, Bolaños-Palmieri P, Siegerist F, Endlich N, Haller H, Schiffer M
Citation:
Kidney Int. 2019 Mar 8. pii: S0085-2538(19)30232-7. doi: 10.1016/j.kint.2019.02.013. [Epub ahead of print]
Epub:
Yes
Abstract:
Proteinuria can be induced by impairment of any component of the glomerular filtration barrier. To determine the role of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Müller-Deile J, Schenk H, Schroder P, Schulze K, Bolaños-Palmieri P, Siegerist F, Endlich N, Haller H, Schiffer M. Circulating factors cause proteinuria in parabiotic zebrafish. Kidney Int. 2019 Mar 8. pii: S0085-2538(19)30232-7. doi: 10.1016/j.kint.2019.02.013. [Epub ahead of print].

CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications

Authors:
Schmöhl F, Peters V, Schmitt CP, Poschet G, Büttner M, Li X, Weigand T, Poth T, Volk N, Morgenstern J, Fleming T, Nawroth PP, Kroll J
Citation:
Cell Molec Life Sci. 2019;[Epub ahead of print] doi:10.1007/s00018-019-03127-z
Epub:
Yes
Abstract:
The gene CNDP1 was associated with the development of diabetic nephropathy. Its enzyme carnosinase 1 (CN1) primarily hydrolyzes...
Organism or Cell Type:
zebrafish
Citation Extract:
Schmöhl F, Peters V, Schmitt CP, Poschet G, Büttner M, Li X, Weigand T, Poth T, Volk N, Morgenstern J, Fleming T, Nawroth PP, Kroll J. CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications. Cell Molec Life Sci. 2019;[Epub ahead of print] doi:10.1007/s00018-019-03127-z.

Pathway-specific protein domains are predictive for human diseases

Authors:
Shim JE, Kim JH, Shin J, Lee JE, Lee I
Citation:
PLoS Comput Biol. 2019;15(5): e1007052. https://doi.org/10.1371/journal.pcbi.1007052
Epub:
Not Epub
Abstract:
Protein domains are basic functional units of proteins. Many protein domains are pervasive among diverse biological processes,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shim JE, Kim JH, Shin J, Lee JE, Lee I. Pathway-specific protein domains are predictive for human diseases. PLoS Comput Biol. 2019;15(5): e1007052. https://doi.org/10.1371/journal.pcbi.1007052.

PDGF-B: the Missing Piece in the Mosaic of PDGF Family Role in Craniofacial Development

Authors:
Corsinovi D, Giannetti K, Cericola A, Naef V, Ori M
Citation:
Dev Dyn. 2019 May 9. doi: 10.1002/dvdy.47. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: The PDGF family consists of four ligands (PDGF-A to -D) and two tyrosine kinase receptors (PDGFR-α and -β). In...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Corsinovi D, Giannetti K, Cericola A, Naef V, Ori M. PDGF-B: the Missing Piece in the Mosaic of PDGF Family Role in Craniofacial Development. Dev Dyn. 2019 May 9. doi: 10.1002/dvdy.47. [Epub ahead of print].

Alternative splice forms of CTLA-4 induced by antisense mediated splice-switching influences autoimmune diabetes susceptibility in NOD mice

Authors:
Mourich DV, Oda SK, Schnell FJ, Crumley SL, Hauck LL, Moentenich CA, Marshall NB, Hinrichs DJ, Iversen PL
Citation:
Nucleic Acid Ther. 2014 Apr;24(2):114-26. doi: 10.1089/nat.2013.0449. Epub 2014 Feb 4
Epub:
Not Epub
Abstract:
Activated and regulatory T cells express the negative co-stimulatory molecule cytotoxic T-lymphocyte-associated antigen-4 (CTLA...
Organism or Cell Type:
non-obese diabetic (NOD) mice
Citation Extract:
Mourich DV, Oda SK, Schnell FJ, Crumley SL, Hauck LL, Moentenich CA, Marshall NB, Hinrichs DJ, Iversen PL. Alternative splice forms of CTLA-4 induced by antisense mediated splice-switching influences autoimmune diabetes susceptibility in NOD mice. Nucleic Acid Ther. 2014 Apr;24(2):114-26. doi: 10.1089/nat.2013.0449. Epub 2014 Feb 4.

The Reprimo gene family member, reprimo-like (rprml), is required for blood development in embryonic zebrafish

Authors:
Stanic K, Reig G, Wichmann IA, Opazo JC, Owen GI, Corvalán AH, Concha ML, Amigo JD
Citation:
Sci Rep. 2019;9(1):7131. doi:10.1038/s41598-019-43436-8
Epub:
Not Epub
Abstract:
The Reprimo gene family comprises a group of single-exon genes for which their physiological function remains poorly understood...
Citation Extract:
Stanic K, Reig G, Wichmann IA, Opazo JC, Owen GI, Corvalán AH, Concha ML, Amigo JD. The Reprimo gene family member, reprimo-like (rprml), is required for blood development in embryonic zebrafish. Sci Rep. 2019;9(1):7131. doi:10.1038/s41598-019-43436-8.

Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis

Authors:
Heath CM, Wignall SM
Citation:
Mol Biol Cell. 2019 May 8:mbcE18100666. doi: 10.1091/mbc.E18-10-0666. [Epub ahead of print]
Epub:
Yes
Abstract:
Oocytes of many species lack centrioles, and therefore form acentriolar spindles. Despite the necessity of oocyte meiosis for...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Heath CM, Wignall SM. Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis. Mol Biol Cell. 2019 May 8:mbcE18100666. doi: 10.1091/mbc.E18-10-0666. [Epub ahead of print].

Endoglin is a conserved regulator of vasculogenesis in zebrafish-Implications for hereditary haemorrhagic telangiectasia

Authors:
Zhang D, Zhou F, Zhao X, Liu B, Chen J, Yang J
Citation:
Biosci Rep. 2019 May 7. pii: BSR20182320. doi: 10.1042/BSR20182320. [Epub ahead of print]
Epub:
Yes
Abstract:
Hereditary haemorrhagic telangiectasia (HHT) is a progressive vascular disease with high mortality and prevalence. There is no...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang D, Zhou F, Zhao X, Liu B, Chen J, Yang J. Endoglin is a conserved regulator of vasculogenesis in zebrafish-Implications for hereditary haemorrhagic telangiectasia. Biosci Rep. 2019 May 7. pii: BSR20182320. doi: 10.1042/BSR20182320. [Epub ahead of print].

Talin1 is required for cardiac Z-disk stabilization and endothelial integrity in zebrafish

Authors:
Wu Q, Zhang J, Koh W, Yu Q, Zhu X, Amsterdam A, Davis GE, Arnaout MA, Xiong JW
Citation:
FASEB J. 2015 Dec;29(12):4989-5005. doi: 10.1096/fj.15-273409. Epub 2015 Aug 26
Epub:
Not Epub
Abstract:
Talin (tln) binds and activates integrins to couple extracellular matrix-bound integrins to the cytoskeleton; however, its role...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu Q, Zhang J, Koh W, Yu Q, Zhu X, Amsterdam A, Davis GE, Arnaout MA, Xiong JW. Talin1 is required for cardiac Z-disk stabilization and endothelial integrity in zebrafish. FASEB J. 2015 Dec;29(12):4989-5005. doi: 10.1096/fj.15-273409. Epub 2015 Aug 26.

GIPC proteins negatively modulate Plexind1 signaling during vascular development

Authors:
Carretero-Ortega J, Chhangawala Z, Hunt S, Narvaez C, Menéndez-González J, Gay CM, Zygmunt T, Li X, Torres-Vázquez J
Citation:
Elife. 2019 May 3;8. pii: e30454. doi: 10.7554/eLife.30454
Epub:
Not Epub
Abstract:
Semaphorins (SEMAs) and their Plexin (PLXN) receptors are central regulators of metazoan cellular communication. SEMA-PLXND1...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Carretero-Ortega J, Chhangawala Z, Hunt S, Narvaez C, Menéndez-González J, Gay CM, Zygmunt T, Li X, Torres-Vázquez J. GIPC proteins negatively modulate Plexind1 signaling during vascular development. Elife. 2019 May 3;8. pii: e30454. doi: 10.7554/eLife.30454.

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