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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Blocking variant surface glycoprotein synthesis alters endoplasmic reticulum exit sites/Golgi homeostasis in Trypanosoma brucei

Authors:
Ooi C-P, Smith TK, Gluenz E, Vasileva Wand NV, Vaughan S, Rudenko G
Citation:
Traffic. 2018;[Epub] doi:10.1111/tra.12561
Epub:
Yes
Abstract:
The predominant secretory cargo of bloodstream form Trypanosoma brucei is variant surface glycoprotein (VSG), comprising ~10%...
Link:
https://onlinelibrary.wiley.com/doi/full/10.1111/tra.12561
Delivery Method:
electroporation
Organism or Cell Type:
Trypanosoma brucei
Citation Extract:
Ooi C-P, Smith TK, Gluenz E, Vasileva Wand NV, Vaughan S, Rudenko G. Blocking variant surface glycoprotein synthesis alters endoplasmic reticulum exit sites/Golgi homeostasis in Trypanosoma brucei. Traffic. 2018;[Epub] doi:10.1111/tra.12561.

An Early Function of Polycystin-2 for Left-Right Organizer Induction in Xenopus

Authors:
Vick P, Kreis J, Schneider I, Tingler M, Getwan M, Thumberger T, Beyer T, Schweickert A, Blum M
Citation:
iScience. 2018;2:76-85. doi:10.1016/j.isci.2018.03.011
Epub:
Not Epub
Abstract:
Nodal signaling controls asymmetric organ placement during vertebrate embryogenesis. Nodal is induced by a leftward fluid flow...
Link:
http://www.cell.com/iscience/abstract/S2589-0042(18)30020-8
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Vick P, Kreis J, Schneider I, Tingler M, Getwan M, Thumberger T, Beyer T, Schweickert A, Blum M. An Early Function of Polycystin-2 for Left-Right Organizer Induction in Xenopus. iScience. 2018;2:76-85. doi:10.1016/j.isci.2018.03.011 .

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

Authors:
Gusev A, Mancuso N, Won H, Kousi M, Finucane HK, Reshef Y, Song L, Safi A, Schizophrenia Working Group of the Psychiatric Genomics Consortium, McCarroll S, Neale BM, Ophoff RA, O’Donovan MC, Crawford GE, Geschwind DH, Katsanis N, Sullivan PF, Pasaniuc B, Price AL
Citation:
Nat Genet. 2018;[Epub ahead of print] doi:10.1038/s41588-018-0092-1
Epub:
Yes
Abstract:
Genome-wide association studies (GWAS) have identified over 100 risk loci for schizophrenia, but the causal mechanisms remain...
Link:
https://www.nature.com/articles/s41588-018-0092-1#Abs1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gusev A, Mancuso N, Won H, Kousi M, Finucane HK, Reshef Y, Song L, Safi A, Schizophrenia Working Group of the Psychiatric Genomics Consortium, McCarroll S, Neale BM, Ophoff RA, O’Donovan MC, Crawford GE, Geschwind DH, Katsanis N, Sullivan PF, Pasaniuc B, Price AL. Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights. Nat Genet. 2018;[Epub ahead of print] doi:10.1038/s41588-018-0092-1.

Transgenic Xenopus laevis Line for In Vivo Labeling of Nephrons within the Kidney

Authors:
Corkins ME, Hannah L. Hanania HL, Krneta-Stankic V, DeLay BD, Pearl EJ, Lee M, Ji H, Davidson AJ, Horb ME, Miller RK
Citation:
Genes. 2018;9(4):197. doi:10.3390/genes9040197
Epub:
Not Epub
Abstract:
Xenopus laevis embryos are an established model for studying kidney development. The nephron structure and genetic pathways...
Link:
http://www.mdpi.com/2073-4425/9/4/197/htm
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Corkins ME, Hannah L. Hanania HL, Krneta-Stankic V, DeLay BD, Pearl EJ, Lee M, Ji H, Davidson AJ, Horb ME, Miller RK. Transgenic Xenopus laevis Line for In Vivo Labeling of Nephrons within the Kidney. Genes. 2018;9(4):197. doi:10.3390/genes9040197.

Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery

Authors:
Wolfe JM, Fadzen CM, Choo Z-N, Rebecca L. Holden RL, Yao M, Hanson GJ, Pentelute BL
Citation:
ACS Cent Sci. 2018;[Epub] doi:10.1021/acscentsci.8b00098
Epub:
Yes
Abstract:
Cell-penetrating peptides (CPPs) can facilitate the intracellular delivery of large therapeutically relevant molecules,...
Link:
https://pubs.acs.org/doi/full/10.1021/acscentsci.8b00098
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: HeLa 654
Citation Extract:
Wolfe JM, Fadzen CM, Choo Z-N, Rebecca L. Holden RL, Yao M, Hanson GJ, Pentelute BL. Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery. ACS Cent Sci. 2018;[Epub] doi:10.1021/acscentsci.8b00098.

Myelination of Neuronal Cell Bodies when Myelin Supply Exceeds Axonal Demand

Authors:
Almeida RG, Pan S, Cole KLH, Williamson JM, Early JJ, Czopka T, Klingseisen A, Chan JR, Lyons DA
Citation:
Curr Biol. 2018;[Epub ahead of print]. doi:10.1016/j.cub.2018.02.068
Epub:
Yes
Abstract:
The correct targeting of myelin is essential for nervous system formation and function. Oligodendrocytes in the CNS myelinate...
Link:
http://www.cell.com/current-biology/fulltext/S0960-9822(18)30254-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Almeida RG, Pan S, Cole KLH, Williamson JM, Early JJ, Czopka T, Klingseisen A, Chan JR, Lyons DA. Myelination of Neuronal Cell Bodies when Myelin Supply Exceeds Axonal Demand. Curr Biol. 2018;[Epub ahead of print]. doi:10.1016/j.cub.2018.02.068.

Terminal Uridylyltransferases Execute Programmed Clearance of Maternal Transcriptome in Vertebrate Embryos

Authors:
Chang H, Yeo Y, Kim J-g, Kim H, Lim J, Lee M, Kim HH, Ohk J, Jeon H-Y, Lee H, Jung H, Kim K-W, Kim VN
Citation:
Molec Cell. 2018;70(1):72-82.e7. doi:10.1016/j.molcel.2018.03.004
Epub:
Not Epub
Abstract:
During the maternal-to-zygotic transition (MZT), maternal RNAs are actively degraded and replaced by newly synthesized zygotic...
Link:
http://www.cell.com/molecular-cell/fulltext/S1097-2765(18)30185-0
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Chang H, Yeo Y, Kim J-g, Kim H, Lim J, Lee M, Kim HH, Ohk J, Jeon H-Y, Lee H, Jung H, Kim K-W, Kim VN. Terminal Uridylyltransferases Execute Programmed Clearance of Maternal Transcriptome in Vertebrate Embryos. Molec Cell. 2018;70(1):72-82.e7. doi:10.1016/j.molcel.2018.03.004.

Xenopus ADAM19 regulates Wnt signaling and neural crest specification by stabilizing ADAM13

Authors:
Li J, Perfetto M, Neuner R, Bahudhanapati H, Christian L, Mathavan K, Bridges LC, Alfandari D, Wei S
Citation:
Development. 2018 Mar 14. pii: dev.158154. doi: 10.1242/dev.158154. [Epub ahead of print]
Epub:
Yes
Abstract:
During vertebrate gastrulation, canonical Wnt signaling induces the formation of neural plate border (NPB). Wnt is also thought...
Link:
http://dev.biologists.org/content/145/7/dev158154
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Li J, Perfetto M, Neuner R, Bahudhanapati H, Christian L, Mathavan K, Bridges LC, Alfandari D, Wei S. Xenopus ADAM19 regulates Wnt signaling and neural crest specification by stabilizing ADAM13. Development. 2018 Mar 14. pii: dev.158154. doi: 10.1242/dev.158154. [Epub ahead of print].

Gon4l regulates notochord boundary formation and cell polarity underlying axis extension by repressing adhesion genes

Authors:
Williams MLK, Sawada A, Budine T, Yin C, Gontarz P, Solnica-Krezel L
Citation:
Nat Comm. 2018;9:1319. doi:10.1038/s41467-018-03715-w
Epub:
Not Epub
Abstract:
Anteroposterior (AP) axis extension during gastrulation requires embryonic patterning and morphogenesis to be spatiotemporally...
Link:
https://www.nature.com/articles/s41467-018-03715-w
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Williams MLK, Sawada A, Budine T, Yin C, Gontarz P, Solnica-Krezel L. Gon4l regulates notochord boundary formation and cell polarity underlying axis extension by repressing adhesion genes. Nat Comm. 2018;9:1319. doi:10.1038/s41467-018-03715-w.

Requirement of zebrafish pcdh10a and pcdh10b in melanocyte precursor migration

Authors:
Williams JS, Hsu JY, Rossi CC, Artinger KB
Citation:
Dev Biol. 2018 Mar 28. pii: S0012-1606(17)30939-9. doi: 10.1016/j.ydbio.2018.03.022. [Epub ahead of print]
Epub:
Yes
Abstract:
Melanocytes derive from neural crest cells, which are a highly migratory population of cells that play an important role in...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160617309399
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Williams JS, Hsu JY, Rossi CC, Artinger KB. Requirement of zebrafish pcdh10a and pcdh10b in melanocyte precursor migration. Dev Biol. 2018 Mar 28. pii: S0012-1606(17)30939-9. doi: 10.1016/j.ydbio.2018.03.022. [Epub ahead of print].

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