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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

DYRK2 displays muscle fiber type specific function during zebrafish early somitogenesis

Authors:
Sun W, Jiao S, Tan X, Zhang P, You F
Citation:
Int J Dev Biol. 2017;61(6-7):459-463. doi: 10.1387/ijdb.160175sj
Epub:
Not Epub
Abstract:
Dual specificity tyrosine-phosphorylation regulated kinase 2 (DYRK2) is a serine/threonine kinase. In zebrafish, DYRK2 is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun W, Jiao S, Tan X, Zhang P, You F. DYRK2 displays muscle fiber type specific function during zebrafish early somitogenesis. Int J Dev Biol. 2017;61(6-7):459-463. doi: 10.1387/ijdb.160175sj.

Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy

Authors:
Marquardt A, Al-Dabet MM, Ghosh S, Kohli S, Manoharan J, ElWakiel A, Gadi I, Bock F, Nazir S, Wang H, Lindquist JA, Nawroth PP, Madhusudhan T, Mertens PR, Shahzad K, Isermann B
Citation:
J Am Soc Nephrol. 2017 Jul 10. pii: ASN.2016101123. doi: 10.1681/ASN.2016101123. [Epub ahead of print]
Epub:
Yes
Abstract:
Established therapies for diabetic nephropathy (dNP) delay but do not prevent its progression. The shortage of established...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Marquardt A, Al-Dabet MM, Ghosh S, Kohli S, Manoharan J, ElWakiel A, Gadi I, Bock F, Nazir S, Wang H, Lindquist JA, Nawroth PP, Madhusudhan T, Mertens PR, Shahzad K, Isermann B. Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy. J Am Soc Nephrol. 2017 Jul 10. pii: ASN.2016101123. doi: 10.1681/ASN.2016101123. [Epub ahead of print].

Role of Mad2 expression during the early development of the sea urchin

Authors:
Bronchain O, Jdey W, Caraty L, Ciapa
Citation:
Int J Dev Biol. B2017;61(6-7):451-457. doi: 10.1387/ijdb.170053bc
Epub:
Not Epub
Abstract:
Mitotic arrest deficient 2 (Mad2) belongs to the spindle assembly checkpoint (SAC), a mechanism that blocks progression of the...
Delivery Method:
microinjection
Organism or Cell Type:
Paracentrotus lividus (sea urchin)
Citation Extract:
Bronchain O, Jdey W, Caraty L, Ciapa. Role of Mad2 expression during the early development of the sea urchin. Int J Dev Biol. B2017;61(6-7):451-457. doi: 10.1387/ijdb.170053bc.

A functional approach to understanding the role of NCKX5 in Xenopus pigmentation

Authors:
Williams RM, Winkfein RJ, Ginger RS, Green MR, Schnetkamp PP, Wheeler GN
Citation:
PLoS One. 2017 Jul 10;12(7):e0180465. doi: 10.1371/journal.pone.0180465. eCollection 2017
Epub:
Not Epub
Abstract:
NCKX5 is an ion exchanger expressed mostly in pigment cells; however, the functional role for this protein in melanogenesis is...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Williams RM, Winkfein RJ, Ginger RS, Green MR, Schnetkamp PP, Wheeler GN. A functional approach to understanding the role of NCKX5 in Xenopus pigmentation. PLoS One. 2017 Jul 10;12(7):e0180465. doi: 10.1371/journal.pone.0180465. eCollection 2017.

Acetylcholinesterase plays a non-neuronal, non-esterase role in organogenesis

Authors:
Pickett MA, Dush MK, Nascone-Yoder NM
Citation:
Development. 2017 Jul 6. pii: dev.149831. doi: 10.1242/dev.149831. [Epub ahead of print]
Epub:
Yes
Abstract:
Acetylcholinesterase (AChE) is crucial for degrading acetylcholine at cholinergic synapses. In vitro studies suggest that, in...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Pickett MA, Dush MK, Nascone-Yoder NM. Acetylcholinesterase plays a non-neuronal, non-esterase role in organogenesis. Development. 2017 Jul 6. pii: dev.149831. doi: 10.1242/dev.149831. [Epub ahead of print].

Frizzled 3 acts upstream of Alcam during embryonic eye development

Authors:
Seigfried FA, Cizelsky W, Pfister AS, Dietmann P, Walther P, Kühl M, Kühl SJ
Citation:
Dev Biol. 2017 Jun 1;426(1):69-83. doi: 10.1016/j.ydbio.2017.04.004. Epub 2017 Apr 17
Epub:
Not Epub
Abstract:
Formation of a functional eye during vertebrate embryogenesis requires different processes such as cell differentiation, cell...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Seigfried FA, Cizelsky W, Pfister AS, Dietmann P, Walther P, Kühl M, Kühl SJ. Frizzled 3 acts upstream of Alcam during embryonic eye development. Dev Biol. 2017 Jun 1;426(1):69-83. doi: 10.1016/j.ydbio.2017.04.004. Epub 2017 Apr 17.

PDGF controls contact inhibition of locomotion by regulating N-cadherin during neural crest migration

Authors:
Bahm I, Barriga EH, Frolov A, Theveneau E, Frankel P, Mayor R.
Citation:
Development. 2017 Jul 1;144(13):2456-2468. doi: 10.1242/dev.147926. Epub 2017 May 19
Epub:
Not Epub
Abstract:
A fundamental property of neural crest (NC) migration is contact inhibition of locomotion (CIL), a process by which cells...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bahm I, Barriga EH, Frolov A, Theveneau E, Frankel P, Mayor R.. PDGF controls contact inhibition of locomotion by regulating N-cadherin during neural crest migration. Development. 2017 Jul 1;144(13):2456-2468. doi: 10.1242/dev.147926. Epub 2017 May 19.

Daam1 regulates fascin for actin assembly in mouse oocyte meiosis

Authors:
Lu Y, Zhang Y, Pan MH, Kim NH, Sun SC, Cui XS
Citation:
Cell Cycle. 2017 Jul 6:0. doi: 10.1080/15384101.2017.1325045. [Epub ahead of print]
Epub:
Yes
Abstract:
As a formin protein, Daam1 (Dishevelled-associated activator of morphogenesis 1) is reported to regulate series of cell...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Lu Y, Zhang Y, Pan MH, Kim NH, Sun SC, Cui XS. Daam1 regulates fascin for actin assembly in mouse oocyte meiosis. Cell Cycle. 2017 Jul 6:0. doi: 10.1080/15384101.2017.1325045. [Epub ahead of print].

MG132-induced progerin clearance is mediated by autophagy activation and splicing regulation

Authors:
Harhouri K, Navarro C, Depetris D, Mattei MG, Nissan X, Cau P, De Sandre-Giovannoli A, Lévy N
Citation:
EMBO Mol Med. 2017 Jul 3. pii: e201607315. doi: 10.15252/emmm.201607315. [Epub ahead of print]
Epub:
Yes
Abstract:
Hutchinson-Gilford progeria syndrome (HGPS) is a lethal premature and accelerated aging disease caused by a de novo point...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: primary dermal fibroblasts
Citation Extract:
Harhouri K, Navarro C, Depetris D, Mattei MG, Nissan X, Cau P, De Sandre-Giovannoli A, Lévy N. MG132-induced progerin clearance is mediated by autophagy activation and splicing regulation. EMBO Mol Med. 2017 Jul 3. pii: e201607315. doi: 10.15252/emmm.201607315. [Epub ahead of print].

A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome

Authors:
Di Gioia SA, Connors S, Matsunami N, Cannavino J, Rose MF, Gilette NM, Artoni P, de Macena Sobreira NL, Chan W-M, Webb BD, Robson CD, Cheng L, Van Ryzin C, Ramirez-Martinez A, Payam Mohassel, Leppert M, Scholand MB, Grunseich C, Ferreira CR, Hartman T, Hayes IM, Morgan T, Markie DM, Fagiolini M, Swift A, Chines PS, Speck-Martins CE, Collins FS, Jabs EW, Bönnemann CG, Olson EN, Moebius Syndrome Research Consortium, Carey JC, Robertson SP, Manoli I, Engle EC
Citation:
Nat Comm. 2017;8:16077. doi:10.1038/ncomms16077
Epub:
Not Epub
Abstract:
Multinucleate cellular syncytial formation is a hallmark of skeletal muscle differentiation. Myomaker, encoded by Mymk (Tmem8c...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Di Gioia SA, Connors S, Matsunami N, Cannavino J, Rose MF, Gilette NM, Artoni P, de Macena Sobreira NL, Chan W-M, Webb BD, Robson CD, Cheng L, Van Ryzin C, Ramirez-Martinez A, Payam Mohassel, Leppert M, Scholand MB, Grunseich C, Ferreira CR, Hartman T, Hayes IM, Morgan T, Markie DM, Fagiolini M, Swift A, Chines PS, Speck-Martins CE, Collins FS, Jabs EW, Bönnemann CG, Olson EN, Moebius Syndrome Research Consortium, Carey JC, Robertson SP, Manoli I, Engle EC. A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome. Nat Comm. 2017;8:16077. doi:10.1038/ncomms16077.

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