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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Characterization of TRPA channels in the starfish Patiria pectinifera: involvement of thermally activated TRPA1 in thermotaxis in marine planktonic larvae

Authors:
Saito S, Hamanaka G, Kawai N, Furukawa R, Gojobori J, Tominaga M, Kaneko H, Satta Y
Citation:
Sci Rep. 2017;7:2173. doi:10.1038/s41598-017-02171-8
Epub:
Not Epub
Abstract:
The vast majority of marine invertebrates spend their larval period as pelagic plankton and are exposed to various...
Delivery Method:
microinjection
Organism or Cell Type:
Patiria pectinifera (sea star)
Citation Extract:
Saito S, Hamanaka G, Kawai N, Furukawa R, Gojobori J, Tominaga M, Kaneko H, Satta Y. Characterization of TRPA channels in the starfish Patiria pectinifera: involvement of thermally activated TRPA1 in thermotaxis in marine planktonic larvae. Sci Rep. 2017;7:2173. doi:10.1038/s41598-017-02171-8.

Quantitative determination of AVI-7100 (Radavirsen), a phosphorodiamidate morpholino oligomer (PMOplus®), in human plasma using LC-MS/MS

Authors:
Meng M, Zhang J, Liu A, Reuschel S, Sazani P, Wong M
Citation:
Bioanalysis. 2017 May 18. doi: 10.4155/bio-2016-0289. [Epub ahead of print]
Epub:
Yes
Abstract:
AIM: AVI-7100 (Radavirsen) is a 20-mer phosphorodiamidate morpholino oligomer (PMOplus®) for the treatment of influenza....
Organism or Cell Type:
human
Citation Extract:
Meng M, Zhang J, Liu A, Reuschel S, Sazani P, Wong M. Quantitative determination of AVI-7100 (Radavirsen), a phosphorodiamidate morpholino oligomer (PMOplus®), in human plasma using LC-MS/MS. Bioanalysis. 2017 May 18. doi: 10.4155/bio-2016-0289. [Epub ahead of print].

TGFβ mediated structural remodeling facilitates optic fissure fusion and the necessity of BMP antagonism in this process

Authors:
Knickmeyer MD, Mateo JL, Eckert P, Roussa E, Rahhal B, Zuniga A, Krieglstein K, Wittbrodt J, Heermann S
Citation:
bioRxiv. 2017;doi:10.1101/131599
Epub:
Not Epub
Abstract:
The optic fissure is a transient gap in the developing vertebrate eye, which must be closed as development proceeds. A...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Knickmeyer MD, Mateo JL, Eckert P, Roussa E, Rahhal B, Zuniga A, Krieglstein K, Wittbrodt J, Heermann S. TGFβ mediated structural remodeling facilitates optic fissure fusion and the necessity of BMP antagonism in this process. bioRxiv. 2017;doi:10.1101/131599 .

Ectopically expressed Slc34a2a sense-antisense transcripts cause a cerebellar phenotype in zebrafish embryos depending on RNA complementarity and Dicer

Authors:
Piatek MJ, Henderson V, Fearn A, Chaudhry B, Werner A
Citation:
PLoS ONE. 2017;12(5):e0178219. doi:10.1371/journal.pone.0178219
Epub:
Not Epub
Abstract:
Natural antisense transcripts (NATs) are complementary to protein coding genes and potentially regulate their expression....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Piatek MJ, Henderson V, Fearn A, Chaudhry B, Werner A. Ectopically expressed Slc34a2a sense-antisense transcripts cause a cerebellar phenotype in zebrafish embryos depending on RNA complementarity and Dicer. PLoS ONE. 2017;12(5):e0178219. doi:10.1371/journal.pone.0178219.

Interstitial fluid osmolarity modulates the action of differential tissue surface tension in progenitor cell segregation during gastrulation

Authors:
Krens SFG, Veldhuis JH, Barone V, Čapek D, Maître J-L, Brodland GW, Heisenberg C-P
Citation:
Development. 2017;144:1798-806. doi:10.1242/dev.144964
Epub:
Not Epub
Abstract:
The segregation of different cell types into distinct tissues is a fundamental process in metazoan development. Differences in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Krens SFG, Veldhuis JH, Barone V, Čapek D, Maître J-L, Brodland GW, Heisenberg C-P. Interstitial fluid osmolarity modulates the action of differential tissue surface tension in progenitor cell segregation during gastrulation. Development. 2017;144:1798-806. doi:10.1242/dev.144964.

Differential gene expression along the animal-vegetal axis in the ascidian embryo is maintained by a dual functional protein Foxd

Authors:
Tokuhiro S-i, Tokuoka M, Kobayashi K, Kubo A, Oda-Ishii I, Satou Y
Citation:
PLoS Genet. 2017:13(5):e1006741. https://doi.org/10.1371/journal.pgen.1006741
Epub:
Not Epub
Abstract:
In many animal embryos, a specific gene expression pattern is established along the animal-vegetal axis soon after zygotic...
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis (ascidian)
Citation Extract:
Tokuhiro S-i, Tokuoka M, Kobayashi K, Kubo A, Oda-Ishii I, Satou Y. Differential gene expression along the animal-vegetal axis in the ascidian embryo is maintained by a dual functional protein Foxd. PLoS Genet. 2017:13(5):e1006741. https://doi.org/10.1371/journal.pgen.1006741.

Despic V, Dejung M, Gu M, Krishnan J, Zhang J, Herzel L, Straube K, Gerstein MB, Butter F, Neugebauer KM

Authors:
Dynamic RNA-protein interactions underlie the zebrafish maternal-to-zygotic transition
Citation:
Genome Res. 2017 Apr 5. pii: gr.215954.116. doi: 10.1101/gr.215954.116. [Epub ahead of print]
Epub:
Yes
Abstract:
During the maternal-to-zygotic transition (MZT), transcriptionally silent embryos rely on post-transcriptional regulation of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dynamic RNA-protein interactions underlie the zebrafish maternal-to-zygotic transition. Despic V, Dejung M, Gu M, Krishnan J, Zhang J, Herzel L, Straube K, Gerstein MB, Butter F, Neugebauer KM. Genome Res. 2017 Apr 5. pii: gr.215954.116. doi: 10.1101/gr.215954.116. [Epub ahead of print].

Intracellular uptake of macromolecules by brain lymphatic endothelial cells during zebrafish embryonic development

Authors:
van Lessen M, Shibata-Germanos S, van Impel A, Hawkins TA, Rihel J, Schulte-Merker S
Citation:
Elife. 2017 May 12;6. pii: e25932. doi: 10.7554/eLife.25932. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The lymphatic system controls fluid homeostasis and the clearance of macromolecules from interstitial compartments. In mammals...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
van Lessen M, Shibata-Germanos S, van Impel A, Hawkins TA, Rihel J, Schulte-Merker S. Intracellular uptake of macromolecules by brain lymphatic endothelial cells during zebrafish embryonic development. Elife. 2017 May 12;6. pii: e25932. doi: 10.7554/eLife.25932. [Epub ahead of print].

Integrin beta8 (ITGB8) activates VAV-RAC1 signaling via FAK in the acquisition of endometrial epithelial cell receptivity for blastocyst implantation

Authors:
Kumar V, Soni UK, Maurya VK, Singh K, Jha RK
Citation:
Sci Rep. 2017;7:1885. doi:10.1038/s41598-017-01764-7
Epub:
Not Epub
Abstract:
Integrin beta8 (ITGB8) is involved in the endometrial receptivity. The blastocyst first interacts with the luminal endometrial...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Kumar V, Soni UK, Maurya VK, Singh K, Jha RK. Integrin beta8 (ITGB8) activates VAV-RAC1 signaling via FAK in the acquisition of endometrial epithelial cell receptivity for blastocyst implantation. Sci Rep. 2017;7:1885. doi:10.1038/s41598-017-01764-7.

Evaluation of Amphiphilic Peptide Modified Antisense Morpholino Oligonucleotides In Vitro and in Dystrophic mdx Mice

Authors:
Wang MX, Wu B, Lu P, Shah SN, Tucker JD, Bollinger LE, Lu Q
Citation:
Polymers. 2017;9(5):177. doi:10.3390/polym9050177
Epub:
Not Epub
Abstract:
A series of amphiphilic peptides modified PMO (Pt-PMO) were prepared, and their antisense effect and toxicity were evaluated...
Delivery Method:
peptide linked, Endo-Porter
Organism or Cell Type:
mice mdx, cell culture C2C12E23
Citation Extract:
Wang MX, Wu B, Lu P, Shah SN, Tucker JD, Bollinger LE, Lu Q. Evaluation of Amphiphilic Peptide Modified Antisense Morpholino Oligonucleotides In Vitro and in Dystrophic mdx Mice. Polymers. 2017;9(5):177. doi:10.3390/polym9050177.

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