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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC)
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Citation:
eLife. 2017;6:e22706. doi:10.7554/eLife.22706 Epub:
Not Epub Abstract:
Elucidating signaling pathways that regulate cellular metabolism is essential for a better understanding of normal development... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sandoval IT, Delacruz RGC, Miller BN, Hill S, Olson KA, Gabriel AE, Boyd K, Satterfield C, Van Remmen H, Rutter J, Jones DA. A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC). eLife. 2017;6:e22706. doi:10.7554/eLife.22706. |
TNFa/TNFR2 signaling is required for glial ensheathment at the dorsal root entry zone
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Citation:
PLoS Genet. 2017 Apr 5;13(4):e1006712. doi: 10.1371/journal.pgen.1006712. [Epub ahead of print] Epub:
Not Epub Abstract:
Somatosensory information from the periphery is routed to the spinal cord through centrally-projecting sensory axons that cross... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Smith CJ, Wheeler MA, Marjoram L, Bagnat M, Deppmann CD, Kucenas S. TNFa/TNFR2 signaling is required for glial ensheathment at the dorsal root entry zone. PLoS Genet. 2017 Apr 5;13(4):e1006712. doi: 10.1371/journal.pgen.1006712. [Epub ahead of print]. |
The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger
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Citation:
Nat Commun. 2017 Apr 6;8:14911. doi: 10.1038/ncomms14911 Epub:
Not Epub Abstract:
In response to infection and injury, the neutrophil population rapidly expands and then quickly re-establishes the basal state... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Keightley MC, Carradice DP, Layton JE, Pase L, Bertrand JY, Wittig JG, Dakic A, Badrock AP, Cole NJ, Traver D, Nutt SL, McCoey J, Buckle AM, Heath JK, Lieschke GJ. The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger. Nat Commun. 2017 Apr 6;8:14911. doi: 10.1038/ncomms14911. |
Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes
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Citation:
Nat Genet. 2017 Apr 3. doi: 10.1038/ng.3833. [Epub ahead of print] Epub:
Yes Abstract:
We identify SMARCD2 (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily D, member 2), also... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Witzel M, Petersheim D, Fan Y, Bahrami E, Racek T, Rohlfs M, Puchałka J, Mertes C, Gagneur J, Ziegenhain C, Enard W, Stray-Pedersen A, Arkwright PD, Abboud MR, Pazhakh V, Lieschke GJ, Krawitz PM, Dahlhoff M, Schneider MR, Wolf E, Horny HP, Schmidt H, Schäffer AA, Klein C. Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes. Nat Genet. 2017 Apr 3. doi: 10.1038/ng.3833. [Epub ahead of print]. |
Concerted action of neuroepithelial basal shrinkage and active epithelial migration ensures efficient optic cup morphogenesis
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Citation:
Elife. 2017 Apr 4;6. pii: e22689. doi: 10.7554/eLife.22689 Epub:
Not Epub Abstract:
Organ formation is a multi-scale event that involves changes at the intracellular, cellular and tissue level. Organogenesis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sidhaye J, Norden C. Concerted action of neuroepithelial basal shrinkage and active epithelial migration ensures efficient optic cup morphogenesis. Elife. 2017 Apr 4;6. pii: e22689. doi: 10.7554/eLife.22689. |
In vivo characterization of an AHR-dependent long non-coding RNA required for proper Sox9b expression
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Citation:
Mol Pharmacol. 2017 Apr 6. pii: mol.117.108233. doi: 10.1124/mol.117.108233. [Epub ahead of print] Epub:
Yes Abstract:
Xenobiotic activation of the aryl hydrocarbon receptor (AHR) by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) prevents the proper... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Garcia GR, Goodale BC, Wiley MW, La Du JK, Hendrix DA, Tanguay RL. In vivo characterization of an AHR-dependent long non-coding RNA required for proper Sox9b expression. Mol Pharmacol. 2017 Apr 6. pii: mol.117.108233. doi: 10.1124/mol.117.108233. [Epub ahead of print]. |
Effect of empagliflozin on cardiac biomarkers in a zebrafish model of heart failure: clues to the EMPA-REG OUTCOME trial?
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Citation:
Mol Cell Biochem. 2017 Apr 8. doi: 10.1007/s11010-017-3018-9. [Epub ahead of print] Epub:
Yes Abstract:
The sodium-glucose cotransporter 2 (SGLT2) inhibitor empagliflozin was recently reported to reduce heart failure-associated... Organism or Cell Type:
zebrafish Citation Extract: Shi X, Verma S, Yun J, Brand-Arzamendi K, Singh KK, Liu X, Garg A, Quan A, Wen XY. Effect of empagliflozin on cardiac biomarkers in a zebrafish model of heart failure: clues to the EMPA-REG OUTCOME trial?. Mol Cell Biochem. 2017 Apr 8. doi: 10.1007/s11010-017-3018-9. [Epub ahead of print]. |
Ca2+ release via two-pore channel type 2 (TPC2) is required for slow muscle cell myofibrillogenesis and myotomal patterning in intact zebrafish embryos
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Citation:
Dev Biol. 2017 Apr 5. pii: S0012-1606(16)30821-1. doi: 10.1016/j.ydbio.2017.03.031. [Epub ahead of print] Epub:
Yes Abstract:
We recently demonstrated a critical role for two-pore channel type 2 (TPC2)-mediated Ca2+ release during the differentiation of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kelu JJ, Webb SE, Parrington J, Galione A, Miller AL. Ca2+ release via two-pore channel type 2 (TPC2) is required for slow muscle cell myofibrillogenesis and myotomal patterning in intact zebrafish embryos. Dev Biol. 2017 Apr 5. pii: S0012-1606(16)30821-1. doi: 10.1016/j.ydbio.2017.03.031. [Epub ahead of print]. |
Combination of valproic acid and morpholino splice-switching oligonucleotide produces improved outcomes in spinal muscular atrophy patient-derived fibroblasts
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Citation:
Neurochem Int. 2017 Apr 4. pii: S0197-0186(17)30035-9. doi: 10.1016/j.neuint.2017.02.016. [Epub ahead of print] Epub:
Yes Abstract:
Spinal muscular atrophy (SMA), the leading genetic cause of infant mortality worldwide, is characterised by the homozygous loss... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: primary human fibroblasts Citation Extract: Farrelly-Rosch A, Lau CL, Patil N, Turner BJ, Shabanpoor F. Combination of valproic acid and morpholino splice-switching oligonucleotide produces improved outcomes in spinal muscular atrophy patient-derived fibroblasts. Neurochem Int. 2017 Apr 4. pii: S0197-0186(17)30035-9. doi: 10.1016/j.neuint.2017.02.016. [Epub ahead of print]. |
Rescue of Pink1 Deficiency by Stress-Dependent Activation of Autophagy
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Citation:
Cell Chem Biol. 2017 Mar 22. pii: S2451-9456(17)30068-5. doi: 10.1016/j.chembiol.2017.03.005. [Epub ahead of print] Epub:
Yes Abstract:
Stimulating autophagy is a promising therapeutic strategy for slowing the progression of neurodegenerative disease. Neurons are... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang Y, Nguyen DT, Olzomer EM, Poon GP, Cole NJ, Puvanendran A, Phillips BR, Hesselson D. Rescue of Pink1 Deficiency by Stress-Dependent Activation of Autophagy. Cell Chem Biol. 2017 Mar 22. pii: S2451-9456(17)30068-5. doi: 10.1016/j.chembiol.2017.03.005. [Epub ahead of print]. |