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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

HMGB4 is expressed by neuronal cells and affects the expression of genes involved in neural differentiation

Authors:
Rouhiainen A, Zhao X, Vanttola P, Qian K, Kulesskiy E, Kuja-Panula J, Gransalke K, Grönholm M, Unni E, Meistrich M, Tian L, Auvinen P, Rauvala H
Citation:
Sci Rep. 2016;6:32960. doi:10.1038/srep32960
Epub:
Not Epub
Abstract:
HMGB4 is a new member in the family of HMGB proteins that has been characterized in sperm cells, but little is known about its...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: E14 mouse cortical neurons and C2C12 myoblast cells
Citation Extract:
Rouhiainen A, Zhao X, Vanttola P, Qian K, Kulesskiy E, Kuja-Panula J, Gransalke K, Grönholm M, Unni E, Meistrich M, Tian L, Auvinen P, Rauvala H. HMGB4 is expressed by neuronal cells and affects the expression of genes involved in neural differentiation. Sci Rep. 2016;6:32960. doi:10.1038/srep32960.

Gold nanocluster formation using morpholino oligomer as template and assembly agent within hybrid bio-nanomaterials

Authors:
Chakraborty S, Rocha RC, Desireddy A, Artyushkova K, Sanchez T, Perry A III, Atanassov P, Martinez JS
Citation:
RSC Adv. 2016;[Epub ahead of print] doi:10.1039/C6RA16891D
Epub:
Yes
Abstract:
We report the use of a phosphorodiamidate morpholino oligomer as a DNA analogue to template the assembly of a gold nanocluster...
Citation Extract:
Chakraborty S, Rocha RC, Desireddy A, Artyushkova K, Sanchez T, Perry A III, Atanassov P, Martinez JS. Gold nanocluster formation using morpholino oligomer as template and assembly agent within hybrid bio-nanomaterials. RSC Adv. 2016;[Epub ahead of print] doi:10.1039/C6RA16891D .

SIRT2 deacetylates and inhibits the peroxidase activity of peroxiredoxin-1 to sensitize breast cancer cells to oxidant stress inducing agents

Authors:
Fiskus W, Coothankandaswamy V, Chen J, Ma H, Ha K, Saenz DT, Krieger SS, Mill CP, Sun B, Huang P, Mumm JS, Melnick A, Bhalla KN
Citation:
Cancer Res. 2016 Aug 8. pii: canres.0126.2016. [Epub ahead of print] doi:10.1158/0008-5472.CAN-16-0126
Epub:
Yes
Abstract:
SIRT2 is a protein deacetylase with tumor suppressor activity in breast and liver tumors where it is mutated, however, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fiskus W, Coothankandaswamy V, Chen J, Ma H, Ha K, Saenz DT, Krieger SS, Mill CP, Sun B, Huang P, Mumm JS, Melnick A, Bhalla KN. SIRT2 deacetylates and inhibits the peroxidase activity of peroxiredoxin-1 to sensitize breast cancer cells to oxidant stress inducing agents. Cancer Res. 2016 Aug 8. pii: canres.0126.2016. [Epub ahead of print] doi:10.1158/0008-5472.CAN-16-0126.

Experimental Dissection of Metalloproteinase Inhibition-Mediated and Toxic Effects of Phenanthroline on Zebrafish Development

Authors:
Ellis TR, Crawford BD
Citation:
Int J Mol Sci. 2016;17(9):1503. doi:10.3390/ijms17091503
Epub:
Not Epub
Abstract:
Metalloproteinases are zinc-dependent endopeptidases that function as primary effectors of tissue remodeling, cell-signaling,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ellis TR, Crawford BD. Experimental Dissection of Metalloproteinase Inhibition-Mediated and Toxic Effects of Phenanthroline on Zebrafish Development. Int J Mol Sci. 2016;17(9):1503. doi:10.3390/ijms17091503.

Steering cell migration by alternating blebs and actin-rich protrusions

Authors:
Diz-Muñoz A, Romanczuk P, Yu W, Bergert M, Ivanovitch K, Salbreux G, Heisenberg CP, Paluch EK
Citation:
BMC Biol. 2016 Sep 2;14:74. doi: 10.1186/s12915-016-0294-x
Epub:
Not Epub
Abstract:
BACKGROUND: High directional persistence is often assumed to enhance the efficiency of chemotactic migration. Yet, cells in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Diz-Muñoz A, Romanczuk P, Yu W, Bergert M, Ivanovitch K, Salbreux G, Heisenberg CP, Paluch EK. Steering cell migration by alternating blebs and actin-rich protrusions. BMC Biol. 2016 Sep 2;14:74. doi: 10.1186/s12915-016-0294-x.

Chromosome 5q33 deletions associated with congenital heart defects

Authors:
Starkovich M, Lalani SR, Mercer CL, Scott DA
Citation:
Am J Med Genet A. 2016 Sep 2. doi: 10.1002/ajmg.a.37957. [Epub ahead of print]
Epub:
Yes
Abstract:
Congenital heart defects (CHD) are present in over 1% of all newborns and are the leading cause of birth-defect-related deaths...
Organism or Cell Type:
zebrafish
Citation Extract:
Starkovich M, Lalani SR, Mercer CL, Scott DA. Chromosome 5q33 deletions associated with congenital heart defects. Am J Med Genet A. 2016 Sep 2. doi: 10.1002/ajmg.a.37957. [Epub ahead of print].

Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at Cilia

Authors:
del Viso F, Huang F, Myers J, Chalfant M, Zhang Y, Reza N, Bewersdorf J, Lusk CP, Khokha MK
Citation:
Dev Cell. 2016;[Epub ahead of print]. doi:10.1016/j.devcel.2016.08.002
Epub:
Yes
Abstract:
Human genomics is identifying candidate genes for congenital heart disease (CHD), but discovering the underlying mechanisms...
Organism or Cell Type:
zebrafish
Citation Extract:
del Viso F, Huang F, Myers J, Chalfant M, Zhang Y, Reza N, Bewersdorf J, Lusk CP, Khokha MK. Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at Cilia. Dev Cell. 2016;[Epub ahead of print]. doi:10.1016/j.devcel.2016.08.002.

Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis

Authors:
Cox AG, Tsomides A, Kim AJ, Saunders D, Hwang KL, Evason KJ, Heidel J, Brown KK, Yuan M, Lien EC, Lee BC, Nissim S, Dickinson B, Chhangawala S, Changh CJ, Asara JM, Houvras Y, Gladyshev VN, Goessling W.
Citation:
Proc Natl Acad Sci USA. 2016;[Epub ahead of print] doi:10.1073/pnas.1600204113
Epub:
Yes
Abstract:
Selenium, an essential micronutrient known for its cancer prevention properties, is incorporated into a class of selenocysteine...
Organism or Cell Type:
zebrafish
Citation Extract:
Cox AG, Tsomides A, Kim AJ, Saunders D, Hwang KL, Evason KJ, Heidel J, Brown KK, Yuan M, Lien EC, Lee BC, Nissim S, Dickinson B, Chhangawala S, Changh CJ, Asara JM, Houvras Y, Gladyshev VN, Goessling W.. Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis. Proc Natl Acad Sci USA. 2016;[Epub ahead of print] doi:10.1073/pnas.1600204113.

Morphology and Gene Expression Screening with Morpholinos in Zebrafish Embryos

Authors:
Tseng LC, Tang CH, Jiang YJ
Citation:
Methods Mol Biol. 2016;1470:213-24. doi: 10.1007/978-1-4939-6337-9_17
Epub:
Not Epub
Abstract:
High-throughput screening with a loss-of-function strategy is a logical and efficient way to identify novel genes involved in...
Organism or Cell Type:
zebrafish
Citation Extract:
Tseng LC, Tang CH, Jiang YJ. Morphology and Gene Expression Screening with Morpholinos in Zebrafish Embryos. Methods Mol Biol. 2016;1470:213-24. doi: 10.1007/978-1-4939-6337-9_17.

Identification of p53-target genes in Danio rerio

Authors:
Mandriani B, Castellana S, Rinaldi C, Manzoni M, Venuto S, Rodriguez-Aznar E, Galceran J, Nieto MA, Borsani G, Monti E, Mazza T, Merla G, Micale L
Citation:
Sci Rep. 2016;6:32474. doi:10.1038/srep32474
Epub:
Not Epub
Abstract:
To orchestrate the genomic response to cellular stress signals, p53 recognizes and binds to DNA containing specific and well-...
Organism or Cell Type:
zebrafish
Citation Extract:
Mandriani B, Castellana S, Rinaldi C, Manzoni M, Venuto S, Rodriguez-Aznar E, Galceran J, Nieto MA, Borsani G, Monti E, Mazza T, Merla G, Micale L. Identification of p53-target genes in Danio rerio. Sci Rep. 2016;6:32474. doi:10.1038/srep32474.

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