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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12390 scientific papers returned from the database with the search filters currently being used below.

Proprotein Convertase Subtilisin/Kexin Type 7 (PCSK7) Is Essential for the Zebrafish Development and Bioavailability of Transforming Growth Factor Beta 1a (TGFß1a)

Authors:
Turpeinen H, Oksanen A, Kivinen V, Kukkurainen S, Uusimaki A, Ramet M, Parikka M, Hytonen VP, Nykter M, Pesu M
Citation:
J Biol Chem. 2013 Dec 20;288(51):36610-23. doi: 10.1074/jbc.M113.453183. Epub 2013 Oct 31
Epub:
Yes
Abstract:
Proprotein convertase subtilisin/kexin (PCSK) enzymes convert proproteins into bioactive end-products. While other PCSK enzymes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Turpeinen H, Oksanen A, Kivinen V, Kukkurainen S, Uusimaki A, Ramet M, Parikka M, Hytonen VP, Nykter M, Pesu M. Proprotein Convertase Subtilisin/Kexin Type 7 (PCSK7) Is Essential for the Zebrafish Development and Bioavailability of Transforming Growth Factor Beta 1a (TGFß1a). J Biol Chem. 2013 Dec 20;288(51):36610-23. doi: 10.1074/jbc.M113.453183. Epub 2013 Oct 31.

Fgf receptors Fgfr1a and Fgfr2 control the function of pharyngeal endoderm in late cranial cartilage development

Authors:
Larbuisson A, Dalcq J, Martial JA, Muller M
Citation:
Differentiation. 2013 Oct 28. doi:pii: S0301-4681(13)00063-7. 10.1016/j.diff.2013.07.006. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cranial cartilage derives mainly from cranial neural crest cells and its formation requires fibroblast growth factor (Fgf)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Larbuisson A, Dalcq J, Martial JA, Muller M. Fgf receptors Fgfr1a and Fgfr2 control the function of pharyngeal endoderm in late cranial cartilage development. Differentiation. 2013 Oct 28. doi:pii: S0301-4681(13)00063-7. 10.1016/j.diff.2013.07.006. [Epub ahead of print].

Enhancing the Function of CD34+ Cells by Targeting Plasminogen Activator Inhibitor-1

Authors:
Hazra S, Stepps V, Bhatwadekar AD, Caballero S, Boulton ME, Higgins PJ, Nikonova EV, Pepine CJ, Thut C, Finney EM, Stone DJ, Bartelmez SH, Grant MB
Citation:
PLoS ONE. 2013;8(11):e79067. doi:10.1371/journal.pone.0079067
Epub:
Not Epub
Abstract:
Previously, we showed that transient inhibition of TGF- β1 resulted in correction of key aspects of diabetes-induced CD34+ cell...
Organism or Cell Type:
Cultured CD34+ cells
Citation Extract:
Hazra S, Stepps V, Bhatwadekar AD, Caballero S, Boulton ME, Higgins PJ, Nikonova EV, Pepine CJ, Thut C, Finney EM, Stone DJ, Bartelmez SH, Grant MB. Enhancing the Function of CD34+ Cells by Targeting Plasminogen Activator Inhibitor-1. PLoS ONE. 2013;8(11):e79067. doi:10.1371/journal.pone.0079067.

Essential roles of LEM-domain protein MAN1 during organogenesis in Xenopus laevis and overlapping functions of emerin

Authors:
Reil M, Dabauvalle M-C
Citation:
Eur J Cell Biol. 2013;[Epub ahead of print] doi:10.1016/j.ejcb.2013.10.008
Epub:
Not Epub
Abstract:
Mutations in nuclear envelope proteins are linked to an increasing number of human diseases, called envelopathies. Mutations in...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Reil M, Dabauvalle M-C. Essential roles of LEM-domain protein MAN1 during organogenesis in Xenopus laevis and overlapping functions of emerin. Eur J Cell Biol. 2013;[Epub ahead of print] doi:10.1016/j.ejcb.2013.10.008.

Neurotrophic factor NT-3 displays a non-canonical cell guidance signalling function for cephalic neural crest cells

Authors:
Zanin JP, Battiato NL, Rovasio RA
Citation:
Euro J Cell Biol. 2013;[Epub ahead of print] doi:10.1016/j.ejcb.2013.10.006
Epub:
Not Epub
Abstract:
Chemotactic cell migration is triggered by extracellular concentration gradients of molecules segregated by target fields....
Delivery Method:
electroporation
Organism or Cell Type:
Chick
Citation Extract:
Zanin JP, Battiato NL, Rovasio RA. Neurotrophic factor NT-3 displays a non-canonical cell guidance signalling function for cephalic neural crest cells. Euro J Cell Biol. 2013;[Epub ahead of print] doi:10.1016/j.ejcb.2013.10.006.

Muscleblind-like 1 activates insulin receptor exon 11 inclusion by enhancing U2AF65 binding and splicing of the upstream intron

Authors:
Echeverria GV, Cooper TA
Citation:
Nucl Acids Res. 2013;[Epub ahead of print] doi:10.1093/nar/gkt1020
Epub:
Not Epub
Abstract:
Alternative splicing regulates developmentally and tissue-specific gene expression programs, disruption of which have been...
Organism or Cell Type:
Cell-free system
Citation Extract:
Echeverria GV, Cooper TA. Muscleblind-like 1 activates insulin receptor exon 11 inclusion by enhancing U2AF65 binding and splicing of the upstream intron. Nucl Acids Res. 2013;[Epub ahead of print] doi:10.1093/nar/gkt1020.

Genome Wide Analysis Reveals Zic3 Interaction with Distal Regulatory Elements of Stage Specific Developmental Genes in Zebrafish

Authors:
Winata CL, Kondrychyn I, Kumar V, Srinivasan KG, Orlov Y, Ravishankar A, Prabhakar S, Stanton LW, Korzh V, Mathavan S
Citation:
PLoS Genet. 2013;9(10):e1003852. doi:10.1371/journal.pgen.1003852
Epub:
Not Epub
Abstract:
Zic3 regulates early embryonic patterning in vertebrates. Loss of Zic3 function is known to disrupt gastrulation, left-right...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Winata CL, Kondrychyn I, Kumar V, Srinivasan KG, Orlov Y, Ravishankar A, Prabhakar S, Stanton LW, Korzh V, Mathavan S. Genome Wide Analysis Reveals Zic3 Interaction with Distal Regulatory Elements of Stage Specific Developmental Genes in Zebrafish. PLoS Genet. 2013;9(10):e1003852. doi:10.1371/journal.pgen.1003852.

Teneurin-3 Specifies Morphological and Functional Connectivity of Retinal Ganglion Cells in the Vertebrate Visual System

Authors:
Antinucci P, Nikolaou N, Meyer MP, Hindges R
Citation:
Cell Rep. 2013;[Epub ahead of print] doi:10.1016/j.celrep.2013.09.045
Epub:
Not Epub
Abstract:
In the vertebrate retina, retinal ganglion cells (RGCs) develop stereotypic dendritic arborization patterns and make specific...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Antinucci P, Nikolaou N, Meyer MP, Hindges R. Teneurin-3 Specifies Morphological and Functional Connectivity of Retinal Ganglion Cells in the Vertebrate Visual System. Cell Rep. 2013;[Epub ahead of print] doi:10.1016/j.celrep.2013.09.045.

Morpholinos: studying gene function in the chick

Authors:
Norris A, Streit A
Citation:
Methods. 2014 Apr 1;66(3):454-65. doi: 10.1016/j.ymeth.2013.10.009
Epub:
Not Epub
Abstract:
The use of morpholinos for perturbing gene function in the chick, Gallus gallus, has led to many important discoveries in...
Delivery Method:
electroporation
Organism or Cell Type:
Chick
Citation Extract:
Norris A, Streit A. Morpholinos: studying gene function in the chick. Methods. 2014 Apr 1;66(3):454-65. doi: 10.1016/j.ymeth.2013.10.009.

Modelling of human Wiskott-Aldrich syndrome protein mutants in zebrafish larvae using in vivo live imaging

Authors:
Jones RA, Feng Y, Worth AJ, Thrasher AJ, Burns SO, Martin P
Citation:
J Cell Sci. 2013 Sep 15;126(Pt 18):4077-84. doi: 10.1242/jcs.128728. Epub 2013 Jul 18.
Epub:
Not Epub
Abstract:
Wiskott-Aldrich syndrome (WAS) and X-linked neutropenia (XLN) are immunodeficiencies in which the function of several...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Jones RA, Feng Y, Worth AJ, Thrasher AJ, Burns SO, Martin P. Modelling of human Wiskott-Aldrich syndrome protein mutants in zebrafish larvae using in vivo live imaging. J Cell Sci. 2013 Sep 15;126(Pt 18):4077-84. doi: 10.1242/jcs.128728. Epub 2013 Jul 18. .

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