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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12390 scientific papers returned from the database with the search filters currently being used below.

Developmental defects and neuromuscular alterations due to mitofusin 2 gene (MFN2) silencing in zebrafish: a new model for Charcot-Marie-Tooth type 2A neuropathy

Authors:
Vettori A, Bergamin G, Moro E, Vazza G, Polo G, Tiso N, Argenton F, Mostacciuolo ML
Citation:
Neuromusc Disord. 2011 Jan;21(1):58-67. doi: 10.1016/j.nmd.2010.09.002. Epub 2010 Oct 14
Epub:
Not Epub
Abstract:
The development of new animal models is a crucial step in determining the pathological mechanism underlying neurodegenerative...
Organism or Cell Type:
zebrafish
Citation Extract:
Vettori A, Bergamin G, Moro E, Vazza G, Polo G, Tiso N, Argenton F, Mostacciuolo ML. Developmental defects and neuromuscular alterations due to mitofusin 2 gene (MFN2) silencing in zebrafish: a new model for Charcot-Marie-Tooth type 2A neuropathy. Neuromusc Disord. 2011 Jan;21(1):58-67. doi: 10.1016/j.nmd.2010.09.002. Epub 2010 Oct 14.

Differentiation of zebrafish melanophores depends on transcription factors AP2 alpha and AP2 epsilon

Authors:
Van Otterloo E, Li W, Bonde G, Day KM, Hsu MY, Cornell RA
Citation:
PLoS Genet. 2010 Sep 16;6(9). pii: e1001122
Epub:
Not Epub
Abstract:
A model of the gene-regulatory-network (GRN), governing growth, survival, and differentiation of melanocytes, has emerged from...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Van Otterloo E, Li W, Bonde G, Day KM, Hsu MY, Cornell RA. Differentiation of zebrafish melanophores depends on transcription factors AP2 alpha and AP2 epsilon. PLoS Genet. 2010 Sep 16;6(9). pii: e1001122.

Distinct effectors of platelet-derived growth factor receptor-alpha signaling are required for cell survival during embryogenesis

Authors:
Van Stry M, Kazlauskas A, Schreiber SL, Symes K
Citation:
Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8233-8. Epub 2005 May 26
Epub:
Not Epub
Abstract:
Platelet-derived growth factor receptor (PDGFR) signaling is essential for normal embryonic development in many organisms,...
Organism or Cell Type:
Xenopus
Citation Extract:
Van Stry M, Kazlauskas A, Schreiber SL, Symes K. Distinct effectors of platelet-derived growth factor receptor-alpha signaling are required for cell survival during embryogenesis. Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8233-8. Epub 2005 May 26.

Dithiocarbamates are teratogenic to developing zebrafish through inhibition of lysyl oxidase activity

Authors:
van Boxtel AL, Kamstra JH, Fluitsma DM, Legler J
Citation:
Toxicol Appl Pharmacol. 2009 Dec 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Dithiocarbamates (DTCs) are a class of compounds that are extensively used in agriculture as pesticides. As such humans and...
Organism or Cell Type:
zebrafish
Citation Extract:
van Boxtel AL, Kamstra JH, Fluitsma DM, Legler J. Dithiocarbamates are teratogenic to developing zebrafish through inhibition of lysyl oxidase activity. Toxicol Appl Pharmacol. 2009 Dec 29. [Epub ahead of print].

Dynamics of degeneration and regeneration in developing zebrafish peripheral axons reveals a requirement for extrinsic cell types

Authors:
Villegas R, Martin SM, O'Donnell K, Carrillo S, Sagasti A, Allende ML
Citation:
Neural Dev. 2012;7:19 doi:10.1186/1749-8104-7-19 [provisional pdf]
Epub:
Not Epub
Abstract:
Background Understanding the cellular mechanisms regulating axon degeneration and regeneration is crucial for developing...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Villegas R, Martin SM, O'Donnell K, Carrillo S, Sagasti A, Allende ML. Dynamics of degeneration and regeneration in developing zebrafish peripheral axons reveals a requirement for extrinsic cell types. Neural Dev. 2012;7:19 doi:10.1186/1749-8104-7-19 [provisional pdf].

Emx3 is required for the differentiation of dorsal telencephalic neurons

Authors:
Viktorin G, Chiuchitu C, Rissler M, Varga ZM, Westerfield M
Citation:
Dev Dyn. 2009 Aug;238(8):1984-98
Epub:
Not Epub
Abstract:
emx3 is first expressed in prospective telencephalic cells at the anterior border of the zebrafish neural plate. Knockdown of...
Organism or Cell Type:
zebrafish
Citation Extract:
Viktorin G, Chiuchitu C, Rissler M, Varga ZM, Westerfield M. Emx3 is required for the differentiation of dorsal telencephalic neurons. Dev Dyn. 2009 Aug;238(8):1984-98.

Endothelial cell-specific chemotaxis receptor (ecscr) promotes angioblast migration during vasculogenesis and enhances VEGF receptor sensitivity

Authors:
Verma A, Bhattacharya R, Remadevi I, Li K, Pramanik K, Samant GV, Horswill M, Chun CZ, Zhao B, Wang E, Miao RQ, Mukhopadhyay D, Ramchandran R, Wilkinson GA
Citation:
Blood. 2010 Jan 19. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Endothelial Cell-Specific Chemotaxis Receptor (ECSCR) is a cell surface protein expressed by blood endothelial cells with roles...
Organism or Cell Type:
zebrafish
Citation Extract:
Verma A, Bhattacharya R, Remadevi I, Li K, Pramanik K, Samant GV, Horswill M, Chun CZ, Zhao B, Wang E, Miao RQ, Mukhopadhyay D, Ramchandran R, Wilkinson GA. Endothelial cell-specific chemotaxis receptor (ecscr) promotes angioblast migration during vasculogenesis and enhances VEGF receptor sensitivity. Blood. 2010 Jan 19. [Epub ahead of print].

EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans

Authors:
Van Hoecke A, Schoonaert L, Lemmens R, Timmers M, Staats KA, Laird AS, Peeters E, Philips T, Goris A, Dubois B, Andersen PM, Al-Chalabi A, Thijs V, Turnley AM, van Vught PW, Veldink JH, Hardiman O, Van Den Bosch L, Gonzalez-Perez P, Van Damme P, Brown RH Jr, van den Berg LH, Robberecht W.
Citation:
Nat Med. 2012 Aug 26. doi: 10.1038/nm.2901. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting motor neurons. Disease onset and progression...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Van Hoecke A, Schoonaert L, Lemmens R, Timmers M, Staats KA, Laird AS, Peeters E, Philips T, Goris A, Dubois B, Andersen PM, Al-Chalabi A, Thijs V, Turnley AM, van Vught PW, Veldink JH, Hardiman O, Van Den Bosch L, Gonzalez-Perez P, Van Damme P, Brown RH Jr, van den Berg LH, Robberecht W.. EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans. Nat Med. 2012 Aug 26. doi: 10.1038/nm.2901. [Epub ahead of print].

Etsrp/Etv2 Is Directly Regulated by Foxc1a/b in the Zebrafish Angioblast

Authors:
Veldman MB, Lin S
Citation:
Circ Res. 2011 Dec 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Rationale:Endothelial cells are developmentally derived from angioblasts specified in the mesodermal germ cell layer. The...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Veldman MB, Lin S. Etsrp/Etv2 Is Directly Regulated by Foxc1a/b in the Zebrafish Angioblast. Circ Res. 2011 Dec 1. [Epub ahead of print].

Eye defects in receptor protein-tyrosine phosphatase [alpha] knock-down zebrafish

Authors:
Van Der Sar AM, Zivkovic D, Den Hertog J
Citation:
Dev Dyn. 2002 Feb;223(2):292-297
Epub:
Not Epub
Abstract:
Receptor protein-tyrosine phosphatase alpha (RPTP alpha) is highly expressed in the developing retina of different species, but...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Van Der Sar AM, Zivkovic D, Den Hertog J. Eye defects in receptor protein-tyrosine phosphatase [alpha] knock-down zebrafish. Dev Dyn. 2002 Feb;223(2):292-297.

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