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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Modelling Duchenne muscular dystrophy in MYOD1-converted urine-derived cells treated with 3-deazaneplanocin A hydrochloride
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Citation:
Sci Rep. 2019;9(1):3807. doi:10.1038/s41598-019-40421-z Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a severe muscle disorder characterised by mutations in the DMD gene. Recently, we have... Delivery Method:
Endo-Porter Organism or Cell Type:
human MYOD1-urine-derived cells and MYOD1-converted fibroblasts Citation Extract: Takizawa H, Hara Y, Mizobe Y, Ohno T, Suzuki S, Inoue K, Takeshita E, Shimizu-Motohashi Y, Ishiyama A, Hoshino M, Komaki H, Takeda S, Aoki Y. Modelling Duchenne muscular dystrophy in MYOD1-converted urine-derived cells treated with 3-deazaneplanocin A hydrochloride. Sci Rep. 2019;9(1):3807. doi:10.1038/s41598-019-40421-z. |
bif1, a new BMP signaling inhibitor, regulates embryonic hematopoiesis in the zebrafish
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Citation:
Development. 2019;dev.164103. doi:10.1242/dev.164103 Epub:
Not Epub Abstract:
Hematopoiesis maintains the entire blood system and dysregulation of this process can lead to malignancies (leukemia),... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ghersi JJ, Mahony CB, Bertrand JY. bif1, a new BMP signaling inhibitor, regulates embryonic hematopoiesis in the zebrafish. Development. 2019;dev.164103. doi:10.1242/dev.164103. |
Etv6 activates vegfa expression through positive and negative transcriptional regulatory networks in Xenopus embryos
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Citation:
Nat Commun. 2019 Mar 6;10(1):1083. doi: 10.1038/s41467-019-09050-y Epub:
Not Epub Abstract:
VEGFA signaling controls physiological and pathological angiogenesis and hematopoiesis. Although many context-dependent... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Li L, Rispoli R, Patient R, Ciau-Uitz A, Porcher C. Etv6 activates vegfa expression through positive and negative transcriptional regulatory networks in Xenopus embryos. Nat Commun. 2019 Mar 6;10(1):1083. doi: 10.1038/s41467-019-09050-y. |
L1cam-mediated developmental processes of the nervous system are differentially regulated by proteolytic processing
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Citation:
Sci Rep. 2019 Mar 6;9(1):3716. doi: 10.1038/s41598-019-39884-x Epub:
Not Epub Abstract:
Normal brain development depends on tight temporal and spatial regulation of connections between cells. Mutations in L1cam, a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Linneberg C, Toft CLF, Kjaer-Sorensen K, Laursen LS. L1cam-mediated developmental processes of the nervous system are differentially regulated by proteolytic processing. Sci Rep. 2019 Mar 6;9(1):3716. doi: 10.1038/s41598-019-39884-x. |
Vegfa/vegfr2 signaling is necessary for zebrafish islet vessel development, but is dispensable for beta-cell and alpha-cell formation
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Citation:
Sci Rep. 2019 Mar 5;9(1):3594. doi: 10.1038/s41598-019-40136-1 Epub:
Not Epub Abstract:
The mechanisms underlying zebrafish pancreatic islet vascularization have not been well characterized. We sought to determine... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Toselli CM, Wilkinson BM, Paterson J, Kieffer TJ. Vegfa/vegfr2 signaling is necessary for zebrafish islet vessel development, but is dispensable for beta-cell and alpha-cell formation. Sci Rep. 2019 Mar 5;9(1):3594. doi: 10.1038/s41598-019-40136-1. |
Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/565937 Epub:
Not Epub Abstract:
The Nrf2-driven antioxidant response (AR) is a target of covalent drugs and bioactive native electrophiles. However, much of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Poganik JR, Long MJC, Disare MT, Liu X, Chang S-H, Hla T, Aye Y. Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1. bioRxiv. 2019;[preprint] doi:10.1101/565937. |
A novel L1CAM isoform with angiogenic activity generated by NOVA2-mediated alternative splicing
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Citation:
Elife. 2019 Mar 4;8. pii: e44305. doi: 10.7554/eLife.44305 Epub:
Not Epub Abstract:
The biological players involved in angiogenesis are only partially defined. Here, we report that endothelial cells (ECs)... Delivery Method:
Endo-Porter PEG Organism or Cell Type:
cell culture: mouse lu2EC Citation Extract: Angiolini F, Belloni E, Giordano M, Campioni M, Forneris F, Paola PM, Lupia M, Brandas C, Pradella D, Di Matteo A, Giampietro C, Jodice G, Luise C, Bertalot G, Freddi S, Malinverno M, Irimia M, Moulton JD, Summerton J, Chiapparino A, Ghilardi C, Giavazzi R, Nyqvist D, Gabellini D, Dejana E, Cavallaro U, Ghigna C. A novel L1CAM isoform with angiogenic activity generated by NOVA2-mediated alternative splicing. Elife. 2019 Mar 4;8. pii: e44305. doi: 10.7554/eLife.44305. |
TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy
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Citation:
Cell Death Differ. 2019 Mar 1. doi: 10.1038/s41418-019-0311-z. [Epub ahead of print] Epub:
Yes Abstract:
TAMM41, located within the congenital heart diseases (CHD) sensitive region of 3p25 deletion syndrome, is a mitochondrial... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang RM, Tao J, Zhan M, Yuan H, Wang HH, Chen SJ, Zhu C, de Thé H, Zhou J, Guo Y, Zhu J. TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy. Cell Death Differ. 2019 Mar 1. doi: 10.1038/s41418-019-0311-z. [Epub ahead of print]. |
Exon-mediated activation of transcription starts
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/565184 Epub:
Not Epub Abstract:
The processing of transcripts from mammalian genes often occurs near in time and space to their transcription. Here we... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: mouse fibroblasts Citation Extract: Fiszbein A, Krick KS, Burge CB. Exon-mediated activation of transcription starts. bioRxiv. 2019;[preprint] doi:10.1101/565184. |
GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish
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Citation:
Am J Hum Genet. 2019 Feb 27. pii: S0002-9297(19)30017-5. doi: 10.1016/j.ajhg.2019.01.017. [Epub ahead of print] Epub:
Yes Abstract:
Although the use of model systems for studying the mechanism of mutations that have a large effect is common, we highlight here... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Unlu G, Gamazon ER, Qi X, Levic DS, Bastarache L, Denny JC, Roden DM, Mayzus I, Breyer M, Zhong X, Konkashbaev AI, Rzhetsky A, Knapik EW, Cox NJ. GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish. Am J Hum Genet. 2019 Feb 27. pii: S0002-9297(19)30017-5. doi: 10.1016/j.ajhg.2019.01.017. [Epub ahead of print]. |