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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Functional analysis of zebrafish Microfibril-Associated Glycoprotein-1 (MAGP-1) in vivo reveals roles for microfibrils in both vascular development and function

Authors:
Chen E, Larson JD, Ekker SC
Citation:
Blood. 2006 Jun 1;107(11):4364-74. Epub 2006 Feb 9
Epub:
Not Epub
Abstract:
Mutations in fibrillin-1 result in Marfan Syndrome, demonstrating a critical requirement for microfibrils in vessel structure...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen E, Larson JD, Ekker SC. Functional analysis of zebrafish Microfibril-Associated Glycoprotein-1 (MAGP-1) in vivo reveals roles for microfibrils in both vascular development and function. Blood. 2006 Jun 1;107(11):4364-74. Epub 2006 Feb 9.

Functional characterization of Klippel-Trenaunay syndrome gene AGGF1 identifies a novel angiogenic signaling pathway for specification of vein differentiation during embryogenesis

Authors:
Chen D, Li L, Tu X, Yin Z, Wang Q
Citation:
Hum Mol Genet. 2013 Mar 1;22(5):963-76. doi: 10.1093/hmg/dds501. Epub 2012 Nov 29.
Epub:
Not Epub
Abstract:
Specification of arteries and veins is a key process for establishing functional vasculature during embryogenesis and involves...
Organism or Cell Type:
zebrafish
Citation Extract:
Chen D, Li L, Tu X, Yin Z, Wang Q. Functional characterization of Klippel-Trenaunay syndrome gene AGGF1 identifies a novel angiogenic signaling pathway for specification of vein differentiation during embryogenesis. Hum Mol Genet. 2013 Mar 1;22(5):963-76. doi: 10.1093/hmg/dds501. Epub 2012 Nov 29..

Functional genomic dissection of multimeric protein families in zebrafish

Authors:
Cheng KC, Levenson R, Robishaw JD
Citation:
Dev Dyn. 2003 Nov;228(3):555-67
Epub:
Not Epub
Abstract:
The study of multimeric protein function in the postgenomicera has become complicated by the discovery of multiple isoforms for...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cheng KC, Levenson R, Robishaw JD. Functional genomic dissection of multimeric protein families in zebrafish. Dev Dyn. 2003 Nov;228(3):555-67.

Functional inhibition of UQCRB suppresses angiogenesis in zebrafish

Authors:
Cho YS, Jung HJ, Seok SH, Payumo AY, Chen JK, Kwon HJ
Citation:
Biochem Biophys Res Commun. 2013 Feb 27. doi:pii: S0006-291X(13)00355-0. 10.1016/j.bbrc.2013.02.082. [Epub ahead of print]
Epub:
Not Epub
Abstract:
As a subunit of mitochondrial complex III, UQCRB plays an important role in complex III stability, electron transport, and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cho YS, Jung HJ, Seok SH, Payumo AY, Chen JK, Kwon HJ. Functional inhibition of UQCRB suppresses angiogenesis in zebrafish. Biochem Biophys Res Commun. 2013 Feb 27. doi:pii: S0006-291X(13)00355-0. 10.1016/j.bbrc.2013.02.082. [Epub ahead of print].

G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway

Authors:
Chen M, Philipp M, Wang J, Premont RT, Garrison TR, Caron MG, Lefkowitz RJ, Chen W
Citation:
J Biol Chem. 2009 Dec 11;284(50):35040-8. Epub 2009 Oct 2
Epub:
Not Epub
Abstract:
Wnt ligands conduct their functions in canonical Wnt signaling by binding to two receptors, the single transmembrane low...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen M, Philipp M, Wang J, Premont RT, Garrison TR, Caron MG, Lefkowitz RJ, Chen W. G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway. J Biol Chem. 2009 Dec 11;284(50):35040-8. Epub 2009 Oct 2.

Genetic and Physiologic Dissection of the Vertebrate Cardiac Conduction System

Authors:
Chi NC, Shaw RM, Jungblut B, Huisken J, Ferrer T, Arnaout R, Scott I, Beis D, Xiao T, Baier H, Jan LY, Tristani-Firouzi M, Stainier DY
Citation:
PLoS Biol. 2008 May 13;6(5):e109. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Vertebrate hearts depend on highly specialized cardiomyocytes that form the cardiac conduction system (CCS) to coordinate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chi NC, Shaw RM, Jungblut B, Huisken J, Ferrer T, Arnaout R, Scott I, Beis D, Xiao T, Baier H, Jan LY, Tristani-Firouzi M, Stainier DY. Genetic and Physiologic Dissection of the Vertebrate Cardiac Conduction System. PLoS Biol. 2008 May 13;6(5):e109. [Epub ahead of print].

Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition

Authors:
Chen J, Melton C, Suh N, Oh JS, Horner K, Xie F, Sette C, Blelloch R, Conti M
Citation:
Genes Dev. 2011 Apr 1;25(7):755-66
Epub:
Not Epub
Abstract:
Oocyte maturation, fertilization, and early embryonic development occur in the absence of gene transcription. Therefore, it is...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Chen J, Melton C, Suh N, Oh JS, Horner K, Xie F, Sette C, Blelloch R, Conti M. Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition. Genes Dev. 2011 Apr 1;25(7):755-66.

Genomic selection identifies vertebrate transcription factor Fezf2 binding sites and target genes

Authors:
Chen L, Zheng J, Yang N, Li H, Guo S
Citation:
J Biol Chem. 2011 May 27;286(21):18641-9. Epub 2011 Apr 6
Epub:
Not Epub
Abstract:
Identification of transcription factor targets is critical to understanding gene regulatory networks. Here, we uncover...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen L, Zheng J, Yang N, Li H, Guo S. Genomic selection identifies vertebrate transcription factor Fezf2 binding sites and target genes. J Biol Chem. 2011 May 27;286(21):18641-9. Epub 2011 Apr 6.

Global analysis of aberrant pre-mRNA splicing in glioblastoma using exon expression arrays

Authors:
Cheung HC, Baggerly KA, Tsavachidis S, Bachinski LL, Neubauer VL, Nixon TJ, Aldape KD, Cote GJ, Krahe R
Citation:
BMC Genomics. 2008 May 12;9:216
Epub:
Not Epub
Abstract:
BACKGROUND: Tumor-predominant splice isoforms were identified during comparative in silico sequence analysis of EST clones,...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: human glioma lines, tumors and non-tumor barin
Citation Extract:
Cheung HC, Baggerly KA, Tsavachidis S, Bachinski LL, Neubauer VL, Nixon TJ, Aldape KD, Cote GJ, Krahe R. Global analysis of aberrant pre-mRNA splicing in glioblastoma using exon expression arrays. BMC Genomics. 2008 May 12;9:216.

Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish

Authors:
Chen Q, Jiang L, Li C, Hu D, Bu J, Cai D, Du J
Citation:
PLoS Biol. 2012;10(8): e1001374. doi:10.1371/journal.pbio.1001374
Epub:
Not Epub
Abstract:
Although the brain comprises only 2% of body weight, it receives 15% of cardiac output and consumes 20% of total body oxygen...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen Q, Jiang L, Li C, Hu D, Bu J, Cai D, Du J. Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish. PLoS Biol. 2012;10(8): e1001374. doi:10.1371/journal.pbio.1001374.

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