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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Pharmacological HIF2α inhibition improves VHL disease-associated phenotypes in zebrafish model
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Citation:
J Clin Invest. 2015 Apr 13. pii: 73665. doi: 10.1172/JCI73665. [Epub ahead of print] Epub:
Not Epub Abstract:
Patients with a germline mutation in von Hippel-Lindau (VHL) develop renal cell cancers and hypervascular tumors of the brain,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Martins Metelo A, Noonan HR, Xiang L, Jin Y, Baker R, Kamentsky L, Zhang Y, van Rooijen E, Shin J, Carpenter AE, Yeh JR, Peterson RT, Iliopoulos O. Pharmacological HIF2α inhibition improves VHL disease-associated phenotypes in zebrafish model. J Clin Invest. 2015 Apr 13. pii: 73665. doi: 10.1172/JCI73665. [Epub ahead of print]. |
Adenosine signaling promotes hematopoietic stem and progenitor cell emergence
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Citation:
J Exp Med. 2015;[Epub ahead of print] doi:10.1084/jem.20141528 Epub:
Yes Abstract:
Hematopoietic stem cells (HSCs) emerge from aortic endothelium via the endothelial-to-hematopoietic transition (EHT). The... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jing L, Tamplin OJ, Chen MJ, Deng Q, Patterson S, Kim PG, Durand EM, McNeil A, Green JM, Matsuura S, Ablain J, Brandt MK, Schlaeger TM, Huttenlocher A, Daley GQ, Ravid K, Zon LI. Adenosine signaling promotes hematopoietic stem and progenitor cell emergence. J Exp Med. 2015;[Epub ahead of print] doi:10.1084/jem.20141528 . |
Depletion of melanoma fn14 by oligonucleotide-mediated exon skipping
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Citation:
J Invest Dermatol. 2015;135:S106–S113. doi:10.1038/jid.2015.77 Epub:
Not Epub Abstract:
Fibroblast growth factor inducible 14 (Fn14) is the receptor for the TNF family cytokine TNF-like weak inducer of apoptosis (... Organism or Cell Type:
cell culture: human melanoma cell lines Citation Extract: KM Beck, S Ramaswami, W Zeng and MS Hayden. Depletion of melanoma fn14 by oligonucleotide-mediated exon skipping. J Invest Dermatol. 2015;135:S106–S113. doi:10.1038/jid.2015.77. |
Characterization of Tetratricopeptide Repeat-Containing Proteins Critical for Cilia Formation and Function
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Citation:
PLoS One. 2015 Apr 10;10(4):e0124378. doi: 10.1371/journal.pone.0124378. eCollection 2015 Epub:
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Cilia formation and function require a special set of trafficking machinery termed intraflagellar transport (IFT), consisting... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xu Y, Cao J, Huang S, Feng D, Zhang W, Zhu X, Yan X. Characterization of Tetratricopeptide Repeat-Containing Proteins Critical for Cilia Formation and Function. PLoS One. 2015 Apr 10;10(4):e0124378. doi: 10.1371/journal.pone.0124378. eCollection 2015. |
The Basal Transcription Complex Component TAF3 Transduces Changes in Nuclear Phosphoinositides into Transcriptional Output
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Citation:
Molec Cell. 2015;[Epub ahead of print] doi:10.1016/j.molcel.2015.03.009 Epub:
Yes Abstract:
Phosphoinositides (PI) are important signaling molecules in the nucleus that influence gene expression. However, if and how... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yvette Stijf-Bultsma Y, Sommer L, Tauber M, Baalbaki M, Giardoglou P, Jones DR, Gelato KA, van Pelt J, Shah Z, Rahnamoun H, Toma C, Anderson KE, Hawkins P, Lauberth SM, Haramis A-PG, Hart D, Fischle W, Divecha N. The Basal Transcription Complex Component TAF3 Transduces Changes in Nuclear Phosphoinositides into Transcriptional Output. Molec Cell. 2015;[Epub ahead of print] doi:10.1016/j.molcel.2015.03.009. |
Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination
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Citation:
Am J Hum G. 2015;[Epub ahead of print] doi:10.1016/j.ajhg.2015.03.003 Epub:
Yes Abstract:
Despite recent advances in understanding the genetic bases of microcephaly, a large number of cases of microcephaly remain... Organism or Cell Type:
zebrafish Citation Extract: Nakayama T, Al-Maawali A, El-Quessny M, Rajab A, Khalil S, Stoler JM, Tan W-H, Nasir R, Schmitz-Abe K, Hill RS, Partlow JN, Al-Saffar M, Servattalab S, LaCoursiere CM, Tambunan DE, Coulter ME, Elhosary PC, Gorski G, Barkovich AJ, Markianos K, Poduri A, Mochida GH. Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination. Am J Hum G. 2015;[Epub ahead of print] doi:10.1016/j.ajhg.2015.03.003. |
Deiodinase Knockdown during Early Zebrafish Development Affects Growth, Development, Energy Metabolism, Motility and Phototransduction
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Citation:
PLoS One. 2015 Apr 9;10(4):e0123285. doi: 10.1371/journal.pone.0123285. eCollection 2015 Epub:
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Thyroid hormone (TH) balance is essential for vertebrate development. Deiodinase type 1 (D1) and type 2 (D2) increase and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bagci E, Heijlen M, Vergauwen L, Hagenaars A, Houbrechts AM, Esguerra CV, Blust R, Darras VM, Knapen D. Deiodinase Knockdown during Early Zebrafish Development Affects Growth, Development, Energy Metabolism, Motility and Phototransduction. PLoS One. 2015 Apr 9;10(4):e0123285. doi: 10.1371/journal.pone.0123285. eCollection 2015. |
The Proprotein Convertase Subtilisin/Kexin FurinA Regulates Zebrafish Host Response against Mycobacterium marinum
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Citation:
Infect Immun. April 2015 83:4 1431-1442; Accepted manuscript posted online 26 January 2015, doi: 10.1128/IAI.03135-14 Epub:
Not Epub Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ojanen MJ, Turpeinen H, Cordova ZM, Hammarén MM, Harjula SK, Parikka M, Rämet M, Pesu M. The Proprotein Convertase Subtilisin/Kexin FurinA Regulates Zebrafish Host Response against Mycobacterium marinum. Infect Immun. April 2015 83:4 1431-1442; Accepted manuscript posted online 26 January 2015, doi: 10.1128/IAI.03135-14. |
Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts
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Citation:
Cell. 2015;291-306. doi:10.1016/j.cell.2015.02.019 Epub:
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Cholesterol is dynamically transported among organelles, which is essential for multiple cellular functions. However, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chu B-B, Liao Y-C, Qi W, Xie C, Du X, Wang J, Yang H, Miao H-H, Li B-L, Song B-L. Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts. Cell. 2015;291-306. doi:10.1016/j.cell.2015.02.019. |
Fascin1-dependent Filopodia are required for directional migration of a subset of neural crest cells
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Citation:
PLoS Genet. 2015 Jan 21;11(1):e1004946. doi: 10.1371/journal.pgen.1004946. eCollection 2015 Jan Epub:
Not Epub Abstract:
Directional migration of neural crest (NC) cells is essential for patterning the vertebrate embryo, including the craniofacial... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Boer EF, Howell ED, Schilling TF, Jette CA, Stewart RA. Fascin1-dependent Filopodia are required for directional migration of a subset of neural crest cells. PLoS Genet. 2015 Jan 21;11(1):e1004946. doi: 10.1371/journal.pgen.1004946. eCollection 2015 Jan. |