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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Peptide Nanoparticle Delivery of Charge-Neutral Splice-Switching Morpholino Oligonucleotides
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Citation:
Nucleic Acid Ther. 2015 Jan 16. [Epub ahead of print] Epub:
Yes Abstract:
Oligonucleotide analogs have provided novel therapeutics targeting various disorders. However, their poor cellular uptake... Delivery Method:
peptide nanoparticle Organism or Cell Type:
cell culture: U2OS cells, murine H2K mdx myotubes, human SMA type 1 fibroblasts Citation Extract: Järver P, Zaghloul EM, Arzumanov AA, Saleh AF, McClorey G, Hammond SM, Hällbrink M, Langel Ü, Smith CI, Wood MJ, Gait MJ, Andaloussi SE. Peptide Nanoparticle Delivery of Charge-Neutral Splice-Switching Morpholino Oligonucleotides. Nucleic Acid Ther. 2015 Jan 16. [Epub ahead of print]. |
Mitochondrial Ca2+ uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity
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Citation:
eLife. 2015;4:e04801 doi:10.7554/eLife.04801 Epub:
Not Epub Abstract:
Tightly regulated Ca2+ homeostasis is a prerequisite for proper cardiac function. To dissect the regulatory network of cardiac... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shimizu H, Schredelseker J, Huang J, Lu K, Naghdi S, Lu F, Franklin S, Fiji HDG, Wang K, Zhu H, Tian C, Lin B, Nakano H, Ehrlich A, Nakai J, Stieg AZ, Gimzewski JK, Nakano A, Goldhaber JI, Vondriska TM, Hajnóczky G, Kwon O, Chen J-N. Mitochondrial Ca2+ uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity. eLife. 2015;4:e04801 doi:10.7554/eLife.04801. |
A novel function for Egr4 in posterior hindbrain development
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Citation:
Sci Rep. 2015 Jan 13;5:7750. doi: 10.1038/srep07750 Epub:
Not Epub Abstract:
Segmentation of the vertebrate hindbrain is an evolutionarily conserved process. Here, we identify the transcription factor... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Bae CJ, Jeong J, Saint-Jeannet JP. A novel function for Egr4 in posterior hindbrain development. Sci Rep. 2015 Jan 13;5:7750. doi: 10.1038/srep07750. |
Otoferlin Deficiency In Zebrafish Results In Defects In Balance And Hearing: Rescue Of The Balance And Hearing Phenotype With Full-length And Truncated Forms Of Mouse Otoferlin
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Citation:
Mol Cell Biol. 2015 Jan 12. pii: MCB.01439-14. [Epub ahead of print] Epub:
Yes Abstract:
Sensory hair cells convert mechanical motion into chemical signals. Otoferlin, a six-C2 domain transmembrane protein linked to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chatterjee P, Padmanarayana M, Abdullah N, Holman CL, LaDu J, Tanguay RL, Johnson CP. Otoferlin Deficiency In Zebrafish Results In Defects In Balance And Hearing: Rescue Of The Balance And Hearing Phenotype With Full-length And Truncated Forms Of Mouse Otoferlin. Mol Cell Biol. 2015 Jan 12. pii: MCB.01439-14. [Epub ahead of print]. |
Low-dose exposure to bisphenol A and replacement bisphenol S induces precocious hypothalamic neurogenesis in embryonic zebrafish
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Citation:
Proc Natl Acad Sci U S A. 2015;[Epub ahead of print] doi:10.1073/pnas.1417731112 Epub:
Yes Abstract:
Bisphenol A (BPA), a ubiquitous endocrine disruptor that is present in many household products, has been linked to obesity,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kinch CD, Ibhazehiebo K, Jeong J-H, Habibi HR, Kurrasch DM. Low-dose exposure to bisphenol A and replacement bisphenol S induces precocious hypothalamic neurogenesis in embryonic zebrafish. Proc Natl Acad Sci U S A. 2015;[Epub ahead of print] doi:10.1073/pnas.1417731112. |
Phosphorylation-Dependent Ubiquitination of Paraxial Protocadherin (PAPC) Controls Gastrulation Cell Movements
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Citation:
PLoS ONE. 2015;10(1):e0115111. doi:10.1371/journal.pone.0115111 Epub:
Not Epub Abstract:
Paraxial protocadherin (PAPC) has been shown to be involved in gastrulation cell movements during early embryogenesis. It is... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Kai M, Ueno N, Kinoshita N. Phosphorylation-Dependent Ubiquitination of Paraxial Protocadherin (PAPC) Controls Gastrulation Cell Movements. PLoS ONE. 2015;10(1):e0115111. doi:10.1371/journal.pone.0115111. |
Unexpected link between polyketide synthase and calcium carbonate biomineralization
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Citation:
Zoological Lett. 2015;1:3 doi:10.1186/s40851-014-0001-0 Epub:
Not Epub Abstract:
Introduction: Calcium carbonate biominerals participate in diverse physiological functions. Despite intensive studies, little... Delivery Method:
microinjection Organism or Cell Type:
Medaka and Hemicentrotus pulcherrimus (sea urchin) Citation Extract: Hojo M, Omi A, Hamanaka G, Shindo K, Shimada A, Kondo M, Narita T, Kiyomoto M, Katsuyama Y, Ohnishi Y, Irie N, Takeda H. Unexpected link between polyketide synthase and calcium carbonate biomineralization. Zoological Lett. 2015;1:3 doi:10.1186/s40851-014-0001-0. |
Duox1-Derived H2O2 Modulates Cxcl8 Expression and Neutrophil Recruitment via JNK/c-JUN/AP-1 Signaling and Chromatin Modifications
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Citation:
J Immunol. 2015;[Epub ahead of print] doi:10.4049/jimmunol.1402386 Epub:
Not Epub Abstract:
DUOX1-derived hydrogen peroxide (H2O2) and CXCL8 are two key neutrophil chemoattractants. H2O2 is critical at the early phase,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: de Oliveira S, Boudinot P, Calado Â, Mulero V. Duox1-Derived H2O2 Modulates Cxcl8 Expression and Neutrophil Recruitment via JNK/c-JUN/AP-1 Signaling and Chromatin Modifications. J Immunol. 2015;[Epub ahead of print] doi:10.4049/jimmunol.1402386 . |
Drug-Free Macromolecular Therapeutics Induce Apoptosis of Patient Chronic Lymphocytic Leukemia Cells
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Citation:
Drug Deliv Transl Res. 2014 Dec;4(5-6):389-394 Epub:
Not Epub Abstract:
A new drug-free nanotherapeutic approach for B-cell malignancies was developed. Exposure of B-cells to an anti-CD20 Fab'-... Delivery Method:
cell bathing Organism or Cell Type:
cell culture: human chronic lymphocytic leukemia cells Citation Extract: Chu TW, Kosak KM, Shami PJ, Kopeček J. Drug-Free Macromolecular Therapeutics Induce Apoptosis of Patient Chronic Lymphocytic Leukemia Cells. Drug Deliv Transl Res. 2014 Dec;4(5-6):389-394. |
Cdc42 Mediates Bmp-Induced Sprouting Angiogenesis through Fmnl3-Driven Assembly of Endothelial Filopodia in Zebrafish
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Citation:
Dev Cell. 2015;32(1):109-22. doi:10.1016/j.devcel.2014.11.024 Epub:
Not Epub Abstract:
During angiogenesis in vivo, endothelial cells (ECs) at the tips of vascular sprouts actively extend filopodia that are filled... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wakayama Y, Fukuhara S, Ando K, Matsuda M, Mochizuki N. Cdc42 Mediates Bmp-Induced Sprouting Angiogenesis through Fmnl3-Driven Assembly of Endothelial Filopodia in Zebrafish. Dev Cell. 2015;32(1):109-22. doi:10.1016/j.devcel.2014.11.024. |