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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Dihydrofolate reductase is required for the development of heart and outflow tract in zebrafish

Authors:
Sun S, Gui Y, Jiang Q, Song H
Citation:
Acta Biochim Biophys Sin (Shanghai). 2011 Dec;43(12):957-69. doi: 10.1093/abbs/gmr098
Epub:
Not Epub
Abstract:
Folic acid is very important for embryonic development and folic acid inhibition can cause congenital heart defects in...
Link:
http://abbs.oxfordjournals.org/content/43/12/957.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun S, Gui Y, Jiang Q, Song H. Dihydrofolate reductase is required for the development of heart and outflow tract in zebrafish. Acta Biochim Biophys Sin (Shanghai). 2011 Dec;43(12):957-69. doi: 10.1093/abbs/gmr098.

Smoc2 modulates embryonic myelopoiesis during zebrafish development

Authors:
Mommaerts H, Esguerra CV, Hartmann U, Luyten FP, Tylzanowski P
Citation:
Dev Dyn. 2014;[Epub ahead of print] doi:10.1002/dvdy.24164
Epub:
Yes
Abstract:
Background: SMOC2 is a member of the BM-40 (SPARC) family of matricellular proteins, reported to influence signaling in the...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dvdy.24164/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mommaerts H, Esguerra CV, Hartmann U, Luyten FP, Tylzanowski P. Smoc2 modulates embryonic myelopoiesis during zebrafish development. Dev Dyn. 2014;[Epub ahead of print] doi:10.1002/dvdy.24164.

Tom70 serves as a molecular switch to determine pathological cardiac hypertrophy

Authors:
Li J, Qi M, Li C, Shi D, Zhang D, Xie D, Yuan T, Feng J, Liu Y, Liang D, Xu X, Chen J, Xu L, Zhang H, Ye J, Lv F, Huang J, Peng L, Chen YH
Citation:
Cell Res. 2014 Jul 15. doi: 10.1038/cr.2014.94. [Epub ahead of print]
Epub:
Yes
Abstract:
Pathological cardiac hypertrophy is an inevitable forerunner of heart failure. Regardless of the etiology of cardiac...
Link:
http://www.nature.com/cr/journal/vaop/ncurrent/full/cr201494a.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li J, Qi M, Li C, Shi D, Zhang D, Xie D, Yuan T, Feng J, Liu Y, Liang D, Xu X, Chen J, Xu L, Zhang H, Ye J, Lv F, Huang J, Peng L, Chen YH. Tom70 serves as a molecular switch to determine pathological cardiac hypertrophy. Cell Res. 2014 Jul 15. doi: 10.1038/cr.2014.94. [Epub ahead of print].

Thrombospondin-4 controls matrix assembly during development and Repair of Myotendinous Junctions

Authors:
Subramanian A, Schilling TF
Citation:
Elife. 2014 Jun 18:e02372. doi: 10.7554/eLife.02372. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Tendons are extracellular matrix (ECM)-rich structures that mediate muscle attachments with the skeleton, but surprisingly...
Link:
http://elifesciences.org/content/3/e02372
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Subramanian A, Schilling TF. Thrombospondin-4 controls matrix assembly during development and Repair of Myotendinous Junctions. Elife. 2014 Jun 18:e02372. doi: 10.7554/eLife.02372. [Epub ahead of print].

TGF-β-activated kinase 1 (TAK1) Activation Requires Phosphorylation of Serine 412 by Protein Kinase A Catalytic Subunit α (PKACα) and Protein Kinase X (PRKX)

Authors:
Ouyang C, Nie L, Gu M, Wu A, Han X, Wang X, Shao J, Xia Z
Citation:
J Biol Chem. 2014 Aug 29;289(35):24226-37. doi: 10.1074/jbc.M114.559963. Epub 2014 Jul 15.
Epub:
Yes
Abstract:
TGF-β-activated kinase 1 (TAK1) is a key kinase in mediating toll-like receptors (TLRs) and interleukin-1 receptor (IL-1R)...
Link:
http://www.jbc.org/content/early/2014/07/15/jbc.M114.559963.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ouyang C, Nie L, Gu M, Wu A, Han X, Wang X, Shao J, Xia Z. TGF-β-activated kinase 1 (TAK1) Activation Requires Phosphorylation of Serine 412 by Protein Kinase A Catalytic Subunit α (PKACα) and Protein Kinase X (PRKX). J Biol Chem. 2014 Aug 29;289(35):24226-37. doi: 10.1074/jbc.M114.559963. Epub 2014 Jul 15..

miR-19a replacement rescues cardiac and fin defects in zebrafish model of holt-oram syndrome

Authors:
Chiavacci E, Cremisi F, Guzzolino E, Cellerino A, Baumgart M, D'aurizio R, Pitto L
Citation:
Cardiovasc Res. 2014 Jul 15;103 Suppl 1:S99. doi: 10.1093/cvr/cvu095.1
Epub:
Not Epub
Abstract:
PURPOSE: MicroRNAs (miRNAs) are short, single-stranded RNAs that anneal with complementary sequences in mRNAs thereby...
Link:
http://cardiovascres.oxfordjournals.org/content/103/suppl_1/S99.1.short
Organism or Cell Type:
zebrafish
Citation Extract:
Chiavacci E, Cremisi F, Guzzolino E, Cellerino A, Baumgart M, D'aurizio R, Pitto L. miR-19a replacement rescues cardiac and fin defects in zebrafish model of holt-oram syndrome. Cardiovasc Res. 2014 Jul 15;103 Suppl 1:S99. doi: 10.1093/cvr/cvu095.1.

Genetic Targets of Hydrogen Sulfide in Ventilator-Induced Lung Injury - A Microarray Study

Authors:
Spassov S, Pfeifer D, Strosing K, Ryter S, Hummel M, Faller S, Hoetzel A
Citation:
PLoS One. 2014 Jul 15;9(7):e102401. doi: 10.1371/journal.pone.0102401. eCollection 2014
Epub:
Not Epub
Abstract:
Recently, we have shown that inhalation of hydrogen sulfide (H2S) protects against ventilator-induced lung injury (VILI). In...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0102401
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Spassov S, Pfeifer D, Strosing K, Ryter S, Hummel M, Faller S, Hoetzel A. Genetic Targets of Hydrogen Sulfide in Ventilator-Induced Lung Injury - A Microarray Study. PLoS One. 2014 Jul 15;9(7):e102401. doi: 10.1371/journal.pone.0102401. eCollection 2014.

Heart development: all mesp-ed up

Authors:
Tan H, Wardle F
Citation:
Cardiovasc Res. 2014 Jul 15;103 Suppl 1:S58. doi: 10.1093/cvr/cvu091.8. Epub 2014 Jun 27
Epub:
Not Epub
Abstract:
The mesp family of transcription factors is known to be involved in somite, cardiovascular, and haematopoietic development in...
Link:
http://cardiovascres.oxfordjournals.org/content/103/suppl_1/S58.5
Organism or Cell Type:
zebrafish
Citation Extract:
Tan H, Wardle F. Heart development: all mesp-ed up. Cardiovasc Res. 2014 Jul 15;103 Suppl 1:S58. doi: 10.1093/cvr/cvu091.8. Epub 2014 Jun 27.

Expression and functional role of Ccdc80 in developing heart and in cardiomyopathies

Authors:
Iaccarino D, Fedrigo M, Castellani C, Della Noce I, Carra S, Cotelli F, Thiene G, Angelini A, Schepis F
Citation:
Cardiovasc Res. 2014 Jul 15;103 Suppl 1:S57-8. doi: 10.1093/cvr/cvu091.4. Epub 2014 Jun 27
Epub:
Not Epub
Abstract:
PURPOSE: The gene Coiled Coil Domain Containing 80 (Ccdc80) is highly expressed in the hearts of vertebrates and its role is...
Link:
http://cardiovascres.oxfordjournals.org/content/103/suppl_1/S57.4.short
Organism or Cell Type:
zebrafish
Citation Extract:
Iaccarino D, Fedrigo M, Castellani C, Della Noce I, Carra S, Cotelli F, Thiene G, Angelini A, Schepis F. Expression and functional role of Ccdc80 in developing heart and in cardiomyopathies. Cardiovasc Res. 2014 Jul 15;103 Suppl 1:S57-8. doi: 10.1093/cvr/cvu091.4. Epub 2014 Jun 27.

The DNA helicase Mcm2 is required for cardiac looping

Authors:
Casar Tena T, Blaette T, Philipp M
Citation:
Cardiovasc Res. 2014 Jul 15;103 Suppl 1:S1. doi: 10.1093/cvr/cvu074.2
Epub:
Not Epub
Abstract:
PURPOSE: The morphology and positioning of the heart greatly depends on the establishment of a left-right axis early during...
Link:
http://cardiovascres.oxfordjournals.org/content/103/suppl_1/S1.2
Organism or Cell Type:
zebrafish
Citation Extract:
Casar Tena T, Blaette T, Philipp M. The DNA helicase Mcm2 is required for cardiac looping. Cardiovasc Res. 2014 Jul 15;103 Suppl 1:S1. doi: 10.1093/cvr/cvu074.2.

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