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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy

Authors:
Wishart TM, Mutsaers CA, Riessland M, Reimer MM, Hunter G, Hannam ML, Eaton SL, Fuller HR, Roche SL, Somers E, Morse R, Young PJ, Lamont DL, Hammerschmidt M, Joshi A, Hohenstein P, Morris GE, Parson SH, Skehel PA, Becker T, Robinson IM, Becker CG, Wirth B, Gillingwater TH
Citation:
J Clin Invest. 2014;[Epub ahead of print] doi:10.1172/JCI71318
Epub:
Yes
Abstract:
The autosomal recessive neurodegenerative disease spinal muscular atrophy (SMA) results from low levels of survival motor...
Link:
http://www.jci.org/articles/view/71318
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wishart TM, Mutsaers CA, Riessland M, Reimer MM, Hunter G, Hannam ML, Eaton SL, Fuller HR, Roche SL, Somers E, Morse R, Young PJ, Lamont DL, Hammerschmidt M, Joshi A, Hohenstein P, Morris GE, Parson SH, Skehel PA, Becker T, Robinson IM, Becker CG, Wirth B, Gillingwater TH. Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy. J Clin Invest. 2014;[Epub ahead of print] doi:10.1172/JCI71318 .

Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis

Authors:
Le Guen L, Karpanen T, Schulte D, Harris NC, Koltowska K, Roukens G, Bower NI, van Impel A, Stacker SA, Achen MG, Schulte-Merker S, Hogan BM
Citation:
Development. 2014 Feb 12. [Epub ahead of print]
Epub:
Yes
Abstract:
The VEGFC/VEGFR3 signaling pathway is essential for lymphangiogenesis (the formation of lymphatic vessels from pre-existing...
Link:
http://dev.biologists.org/content/141/6/1239.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Le Guen L, Karpanen T, Schulte D, Harris NC, Koltowska K, Roukens G, Bower NI, van Impel A, Stacker SA, Achen MG, Schulte-Merker S, Hogan BM. Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis. Development. 2014 Feb 12. [Epub ahead of print].

Dynamics of Sonic hedgehog signaling in the ventral spinal cord are controlled by intrinsic changes in source cells requiring Sulfatase 1

Authors:
Al Oustah A, Danesin C, Khouri-Farah N, Farreny M-A, Escalas N, Cochard P, Glise B, Soula C
Citation:
Development. 2014;141:1392-1403. doi:10.1242/dev.101717
Epub:
Not Epub
Abstract:
In the ventral spinal cord, generation of neuronal and glial cell subtypes is controlled by Sonic hedgehog (Shh). This...
Link:
http://dev.biologists.org/content/141/6/1392.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Al Oustah A, Danesin C, Khouri-Farah N, Farreny M-A, Escalas N, Cochard P, Glise B, Soula C. Dynamics of Sonic hedgehog signaling in the ventral spinal cord are controlled by intrinsic changes in source cells requiring Sulfatase 1. Development. 2014;141:1392-1403. doi:10.1242/dev.101717 .

Functions of FMS-like tyrosine kinase 3 (flt3) in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia

Authors:
He B-L, Shi X, Man CH, Ma ACH, Ekker SC, Chow HCH, So CWE, Choi WWL, Zhang W, Zhang Y, Leung AYH
Citation:
Blood. 2014 Apr 17;123(16):2518-29. doi: 10.1182/blood-2013-02-486688. Epub 2014 Mar 3
Epub:
Not Epub
Abstract:
FMS-like tyrosine kinase 3 (FLT3) is expressed in human hematopoietic stem and progenitor cells (HSPC) but its role during...
Link:
http://bloodjournal.hematologylibrary.org/content/early/2014/03/03/blood-2013-02-486688.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
He B-L, Shi X, Man CH, Ma ACH, Ekker SC, Chow HCH, So CWE, Choi WWL, Zhang W, Zhang Y, Leung AYH. Functions of FMS-like tyrosine kinase 3 (flt3) in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia. Blood. 2014 Apr 17;123(16):2518-29. doi: 10.1182/blood-2013-02-486688. Epub 2014 Mar 3.

miR-142-3p balances proliferation and differentiation of mesenchymal cells during lung development

Authors:
Carraro G, Shrestha A, Rostkovius J, Contreras A, Chao CM, El Agha E, Mackenzie B, Dilai S, Guidolin D, Taketo MM, Günther A, Kumar ME, Seeger W, De Langhe S, Barreto G, Bellusci S
Citation:
Development. 2014 Feb 19. [Epub ahead of print]
Epub:
Yes
Abstract:
The regulation of the balance between proliferation and differentiation in the mesenchymal compartment of the lung is largely...
Link:
http://dev.biologists.org/content/141/6/1272.abstract
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
culture: mouse lung explant
Citation Extract:
Carraro G, Shrestha A, Rostkovius J, Contreras A, Chao CM, El Agha E, Mackenzie B, Dilai S, Guidolin D, Taketo MM, Günther A, Kumar ME, Seeger W, De Langhe S, Barreto G, Bellusci S. miR-142-3p balances proliferation and differentiation of mesenchymal cells during lung development. Development. 2014 Feb 19. [Epub ahead of print].

Hyaluronic Acid receptor stabilin-2 regulates erk phosphorylation and arterial - venous differentiation in zebrafish

Authors:
Rost MS, Sumanas S
Citation:
PLoS One. 2014 Feb 28;9(2):e88614. doi: 10.1371/journal.pone.0088614. eCollection 2014
Epub:
Not Epub
Abstract:
The hyaluronic acid receptor for endocytosis Stabilin-2/HARE mediates systemic clearance of multiple glycosaminoglycans from...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0088614
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rost MS, Sumanas S. Hyaluronic Acid receptor stabilin-2 regulates erk phosphorylation and arterial - venous differentiation in zebrafish. PLoS One. 2014 Feb 28;9(2):e88614. doi: 10.1371/journal.pone.0088614. eCollection 2014.

Secretin Stimulates Biliary Cell Proliferation by Regulating Expression of MicroRNA 125b and MicroRNA let7a in Mice

Authors:
Glaser S, Meng F, Han Y, Onori P, Chow BK, Francis H, Venter J, McDaniel K, Marzioni M, Invernizzi P, Ueno Y, Lai JM, Huang L, Standeford H, Alvaro D, Gaudio E, Franchitto A, Alpini G
Citation:
Gastroenterology. 2014 Jun;146(7):1795-808.e12. doi: 10.1053/j.gastro.2014.02.030. Epub 2014 Feb 25.
Epub:
Not Epub
Abstract:
BACKGROUND & AIMS: Proliferating cholangiocytes secrete and respond to neuroendocrine hormones including secretin. We...
Link:
http://www.gastrojournal.org/article/S0016508514002418/fulltext
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse
Citation Extract:
Glaser S, Meng F, Han Y, Onori P, Chow BK, Francis H, Venter J, McDaniel K, Marzioni M, Invernizzi P, Ueno Y, Lai JM, Huang L, Standeford H, Alvaro D, Gaudio E, Franchitto A, Alpini G. Secretin Stimulates Biliary Cell Proliferation by Regulating Expression of MicroRNA 125b and MicroRNA let7a in Mice. Gastroenterology. 2014 Jun;146(7):1795-808.e12. doi: 10.1053/j.gastro.2014.02.030. Epub 2014 Feb 25. .

Clonal Expansion during Staphylococcus aureus Infection Dynamics Reveals the Effect of Antibiotic Intervention

Authors:
McVicker G, Prajsnar TK, Williams A, Wagner NL, Boots M, Renshaw SA, Foster SJ
Citation:
PLoS Pathog. 2014;10(2):e1003959. doi:10.1371/journal.ppat.1003959
Epub:
Not Epub
Abstract:
To slow the inexorable rise of antibiotic resistance we must understand how drugs impact on pathogenesis and influence the...
Link:
http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1003959
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McVicker G, Prajsnar TK, Williams A, Wagner NL, Boots M, Renshaw SA, Foster SJ. Clonal Expansion during Staphylococcus aureus Infection Dynamics Reveals the Effect of Antibiotic Intervention. PLoS Pathog. 2014;10(2):e1003959. doi:10.1371/journal.ppat.1003959.

Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement

Authors:
Reissner KJ, Gipson CD, Tran PK, Knackstedt LA, Scofield MD, Kalivas PW
Citation:
Addic Biol. 2014;[Epub ahead of print] doi:10.1111/adb.12127
Epub:
Yes
Abstract:
Both pre-clinical and clinical studies indicate that N-acetylcysteine (NAC) may be useful in treating relapse to addictive drug...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/adb.12127/abstract
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
rat
Citation Extract:
Reissner KJ, Gipson CD, Tran PK, Knackstedt LA, Scofield MD, Kalivas PW. Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement. Addic Biol. 2014;[Epub ahead of print] doi:10.1111/adb.12127.

FAP20 is an inner junction protein of doublet microtubules essential for both the planar asymmetrical waveform and stability of flagella in Chlamydomonas

Authors:
Yanagisawa H-a, Mathis G, Oda T, Hirono M, Richey EA, Ishikawa H, Marshall WF, Kikkawa M, Qin H
Citation:
Mol Biol Cell. 2014;[Epub ahead of print] doi:10.1091/mbc.E13-08-0464
Epub:
Yes
Abstract:
The axoneme, the conserved core of eukaryotic cilia and flagella, contains highly specialized doublet microtubules (DMTs). A...
Link:
http://www.molbiolcell.org/content/early/2014/02/24/mbc.E13-08-0464.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Yanagisawa H-a, Mathis G, Oda T, Hirono M, Richey EA, Ishikawa H, Marshall WF, Kikkawa M, Qin H. FAP20 is an inner junction protein of doublet microtubules essential for both the planar asymmetrical waveform and stability of flagella in Chlamydomonas. Mol Biol Cell. 2014;[Epub ahead of print] doi:10.1091/mbc.E13-08-0464.

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