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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

tbx2a Is Required for Specification of Endodermal Pouches during Development of the Pharyngeal Arches

Authors:
Thi Thu HN, Haw Tien SF, Loh SL, Bok Yan JS, Korzh V
Citation:
PLoS ONE. 2013;8(10):e77171. doi:10.1371/journal.pone.0077171
Epub:
Not Epub
Abstract:
Tbx2 is a member of the T-box family of transcription factors essential for embryo- and organogenesis. A deficiency in the...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Thi Thu HN, Haw Tien SF, Loh SL, Bok Yan JS, Korzh V. tbx2a Is Required for Specification of Endodermal Pouches during Development of the Pharyngeal Arches. PLoS ONE. 2013;8(10):e77171. doi:10.1371/journal.pone.0077171 .

NumbL is essential for Xenopus primary neurogenesis

Authors:
Nieber F, Hedderich M, Jahn O, Pieler T, Henningfeld KA
Citation:
BMC Dev Biol. 2013 Oct 14;13(1):36. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Members of the vertebrate Numb family of cell fate determinants serve multiple functions throughout early...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Nieber F, Hedderich M, Jahn O, Pieler T, Henningfeld KA. NumbL is essential for Xenopus primary neurogenesis. BMC Dev Biol. 2013 Oct 14;13(1):36. [Epub ahead of print].

Rapid identification of kidney cyst mutations by whole exome sequencing in zebrafish

Authors:
Ryan S, Willer J, Marjoram L, Bagwell J, Mankiewicz J, Leshchiner I, Goessling W, Bagnat M, Katsanis N
Citation:
Development. 2013;140:4445-4451. doi:10.1242/dev.101170
Epub:
Not Epub
Abstract:
Forward genetic approaches in zebrafish have provided invaluable information about developmental processes. However, the...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Ryan S, Willer J, Marjoram L, Bagwell J, Mankiewicz J, Leshchiner I, Goessling W, Bagnat M, Katsanis N. Rapid identification of kidney cyst mutations by whole exome sequencing in zebrafish. Development. 2013;140:4445-4451. doi:10.1242/dev.101170 .

Semicircular canal morphogenesis in the zebrafish inner ear requires the function of gpr126 (lauscher), an adhesion class G protein-coupled receptor gene

Authors:
Geng FS, Abbas L, Baxendale S, Holdsworth CJ, Swanson AG, Slanchev K, Hammerschmidt M, Topczewski J, Whitfield TT
Citation:
Development. 2013 Sep 25. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Morphogenesis of the semicircular canal ducts in the vertebrate inner ear is a dramatic example of epithelial remodelling in...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Geng FS, Abbas L, Baxendale S, Holdsworth CJ, Swanson AG, Slanchev K, Hammerschmidt M, Topczewski J, Whitfield TT. Semicircular canal morphogenesis in the zebrafish inner ear requires the function of gpr126 (lauscher), an adhesion class G protein-coupled receptor gene. Development. 2013 Sep 25. [Epub ahead of print] .

Gene-Silencing Antisense Oligomers Inhibit Acinetobacter Growth In Vitro and In Vivo

Authors:
Geller BL, Marshall-Batty K, Schnell FJ, McKnight MM, Iversen PL, Greenberg DE
Citation:
J Infect Dis. 2013;[Epub ahead of print] doi:10.1093/infdis/jit460
Epub:
Not Epub
Abstract:
Background. Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMOs) are synthetic DNA/RNA analogues that silence...
Delivery Method:
Peptide-coupled
Organism or Cell Type:
Mice
Citation Extract:
Geller BL, Marshall-Batty K, Schnell FJ, McKnight MM, Iversen PL, Greenberg DE. Gene-Silencing Antisense Oligomers Inhibit Acinetobacter Growth In Vitro and In Vivo. J Infect Dis. 2013;[Epub ahead of print] doi:10.1093/infdis/jit460 .

Bmp signaling exerts opposite effects on cardiac differentiation

Authors:
de Pater E, Ciampricotti M, Priller F, Veerkamp J, Strate I, Smith K, Lagendijk AK, Schilling TF, Herzog W, Abdelilah-Seyfried S, Hammerschmidt M, Bakkers J
Citation:
Circ Res. 2012 Feb 17;110(4):578-87. doi: 10.1161/CIRCRESAHA.111.261172. Epub 2012 Jan 12
Epub:
Not Epub
Abstract:
RATIONALE: The importance for Bmp signaling during embryonic stem cell differentiation into myocardial cells has been...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
de Pater E, Ciampricotti M, Priller F, Veerkamp J, Strate I, Smith K, Lagendijk AK, Schilling TF, Herzog W, Abdelilah-Seyfried S, Hammerschmidt M, Bakkers J. Bmp signaling exerts opposite effects on cardiac differentiation. Circ Res. 2012 Feb 17;110(4):578-87. doi: 10.1161/CIRCRESAHA.111.261172. Epub 2012 Jan 12.

p53-Mediated Biliary Defects Caused by Knockdown of cirh1a, the Zebrafish Homolog of the Gene Responsible for North American Indian Childhood Cirrhosis

Authors:
Wilkins BJ, Lorent K, Matthews RP, Pack M
Citation:
PLoS ONE. 2013;8(10):e77670. doi:10.1371/journal.pone.0077670
Epub:
Not Epub
Abstract:
North American Indian Childhood Cirrhosis (NAIC) is a rare, autosomal recessive, progressive cholestatic disease of infancy...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Wilkins BJ, Lorent K, Matthews RP, Pack M. p53-Mediated Biliary Defects Caused by Knockdown of cirh1a, the Zebrafish Homolog of the Gene Responsible for North American Indian Childhood Cirrhosis. PLoS ONE. 2013;8(10):e77670. doi:10.1371/journal.pone.0077670.

An SMN-dependent U12 splicing event essential for motor circuit function

Authors:
Lotti F, Imlach WL, Saieva L, Beck ES, Hao le T, Li DK, Jiao W, Mentis GZ, Beattie CE, McCabe BD, Pellizzoni L
Citation:
Cell. 2012 Oct 12;151(2):440-54. doi: 10.1016/j.cell.2012.09.012
Epub:
Not Epub
Abstract:
Spinal muscular atrophy (SMA) is a motor neuron disease caused by deficiency of the ubiquitous survival motor neuron (SMN)...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Lotti F, Imlach WL, Saieva L, Beck ES, Hao le T, Li DK, Jiao W, Mentis GZ, Beattie CE, McCabe BD, Pellizzoni L. An SMN-dependent U12 splicing event essential for motor circuit function. Cell. 2012 Oct 12;151(2):440-54. doi: 10.1016/j.cell.2012.09.012.

Tissue damage detection by osmotic surveillance

Authors:
Enyedi B, Kala S, Nikolich-Zugich T, Niethammer P
Citation:
Nat Cell Biol. 2013 Sep;15(9):1123-30. doi: 10.1038/ncb2818. Epub 2013 Aug 11
Epub:
Not Epub
Abstract:
How tissue damage is detected to induce inflammatory responses is unclear. Most studies have focused on damage signals released...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Enyedi B, Kala S, Nikolich-Zugich T, Niethammer P. Tissue damage detection by osmotic surveillance. Nat Cell Biol. 2013 Sep;15(9):1123-30. doi: 10.1038/ncb2818. Epub 2013 Aug 11.

Generation and Dynamics of an Endogenous, Self-Generated Signaling Gradient across a Migrating Tissue

Authors:
Venkiteswaran G, Lewellis SW, Wang J, Reynolds E, Nicholson C, Knaut H
Citation:
Cell. 2013;[Epub ahead of print] doi:10.1016/j.cell.2013.09.046
Epub:
Not Epub
Abstract:
In animals, many cells reach their destinations by migrating toward higher concentrations of an attractant. However, the nature...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Venkiteswaran G, Lewellis SW, Wang J, Reynolds E, Nicholson C, Knaut H. Generation and Dynamics of an Endogenous, Self-Generated Signaling Gradient across a Migrating Tissue. Cell. 2013;[Epub ahead of print] doi:10.1016/j.cell.2013.09.046.

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