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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Ccm3 functions in a manner distinct from Ccm1 and Ccm2 in a zebrafish model of CCM vascular disease

Authors:
Yoruk B, Gillersa BS, Chi NC, Scott IC
Citation:
Dev Biol. 2011;[Epub ahead of print] doi:10.1016/j.ydbio.2011.12.006
Epub:
Not Epub
Abstract:
Cerebral cavernous malformations (CCMs) are vascular anomalies of the central nervous system that arise due to mutations in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yoruk B, Gillersa BS, Chi NC, Scott IC. Ccm3 functions in a manner distinct from Ccm1 and Ccm2 in a zebrafish model of CCM vascular disease. Dev Biol. 2011;[Epub ahead of print] doi:10.1016/j.ydbio.2011.12.006.

Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function

Authors:
Yin H, Moulton HM, Seow Y, Boyd C, Boutilier J, Iverson P, Wood MJ
Citation:
Hum Mol Genet. 2008 Sep 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Antisense oligonucleotides (AOs) have the potential to induce functional dystrophin protein expression via exon skipping by...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice, mdx
Citation Extract:
Yin H, Moulton HM, Seow Y, Boyd C, Boutilier J, Iverson P, Wood MJ. Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function. Hum Mol Genet. 2008 Sep 10. [Epub ahead of print].

Chemical genetics: adding to the developmental biology toolbox

Authors:
Yeh JR, Crews CM
Citation:
Dev Cell. 2003 Jul;5(1):11-9. Review
Epub:
Not Epub
Abstract:
Recent advances in cell and molecular biology have generated important tools to probe developmental questions. In addition, new...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yeh JR, Crews CM. Chemical genetics: adding to the developmental biology toolbox. Dev Cell. 2003 Jul;5(1):11-9. Review.

Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression

Authors:
Yao P, Potdar AA, Arif A, Ray PS, Mukhopadhyay R, Willard B, Xu Y, Yan J, Saidel GM, Fox PL
Citation:
Cell. 2012 Mar 30;149(1):88-100. doi: 10.1016/j.cell.2012.02.018. Epub 2012 Mar 1
Epub:
Not Epub
Abstract:
Posttranscriptional regulatory mechanisms superimpose \"fine-tuning\" control upon \"on-off\" switches...
Delivery Method:
Electroporation
Organism or Cell Type:
cell culture: U937 and human PBM
Citation Extract:
Yao P, Potdar AA, Arif A, Ray PS, Mukhopadhyay R, Willard B, Xu Y, Yan J, Saidel GM, Fox PL. Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression. Cell. 2012 Mar 30;149(1):88-100. doi: 10.1016/j.cell.2012.02.018. Epub 2012 Mar 1.

Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency

Authors:
Yin H, Boisguerin P, Moulton HM, Betts C, Seow Y, Boutilier J, Wang Q, Walsh A, Lebleu B, Wood MJ
Citation:
Mol Ther Nucleic Acids. 2013 Sep 24;2:e124. doi: 10.1038/mtna.2013.51
Epub:
Not Epub
Abstract:
We have recently reported that cell-penetrating peptides (CPPs) and novel chimeric peptides containing CPP (referred as B...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice, mdx
Citation Extract:
Yin H, Boisguerin P, Moulton HM, Betts C, Seow Y, Boutilier J, Wang Q, Walsh A, Lebleu B, Wood MJ. Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency. Mol Ther Nucleic Acids. 2013 Sep 24;2:e124. doi: 10.1038/mtna.2013.51.

CPP-Directed Oligonucleotide Exon Skipping in Animal Models of Duchenne Muscular Dystrophy

Authors:
Yin H, Moulton H, Betts C, Wood M
Citation:
Methods Mol Biol. 2011;683:321-38
Epub:
Not Epub
Abstract:
Antisense oligonucleotides (AOs) are effective splice switching agents and have potential as therapeutics via the exclusion or...
Delivery Method:
peptide-coupled
Citation Extract:
Yin H, Moulton H, Betts C, Wood M. CPP-Directed Oligonucleotide Exon Skipping in Animal Models of Duchenne Muscular Dystrophy. Methods Mol Biol. 2011;683:321-38.

Cross-talk between bone morphogenetic protein and transforming growth factor-beta signaling is essential for exendin-4-induced insulin-positive differentiation of AR42J cells

Authors:
Yew KH, Hembree M, Prasadan K, Preuett B, McFall C, Benjes C, Crowley A, Sharp S, Tulachan S, Mehta S, Tei E, Gittes G
Citation:
J Biol Chem. 2005 Sep 16;280(37):32209-17. Epub 2005 Jul 14
Epub:
Not Epub
Abstract:
A key goal of cellular engineering is to manipulate progenitor cells to become beta-cells, allowing cell replacement therapy to...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
Cell culture: rat AR42J
Citation Extract:
Yew KH, Hembree M, Prasadan K, Preuett B, McFall C, Benjes C, Crowley A, Sharp S, Tulachan S, Mehta S, Tei E, Gittes G. Cross-talk between bone morphogenetic protein and transforming growth factor-beta signaling is essential for exendin-4-induced insulin-positive differentiation of AR42J cells. J Biol Chem. 2005 Sep 16;280(37):32209-17. Epub 2005 Jul 14.

Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish

Authors:
Yoo SK, Deng Q, Cavnar PJ, Wu YI, Hahn KM, Huttenlocher A
Citation:
Dev Cell. 2010 Feb 16;18(2):226-36
Epub:
Not Epub
Abstract:
Cell polarity is crucial for directed migration. Here we show that phosphoinositide 3-kinase (PI(3)K) mediates neutrophil...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yoo SK, Deng Q, Cavnar PJ, Wu YI, Hahn KM, Huttenlocher A. Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish. Dev Cell. 2010 Feb 16;18(2):226-36.

Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors

Authors:
Yu M, Mazor T, Huang H, Huang HT, Kathrein KL, Woo AJ, Chouinard CR, Labadorf A, Akie TE, Moran TB, Xie H, Zacharek S, Taniuchi I, Roeder RG, Kim CF, Zon LI, Fraenkel E, Cantor AB
Citation:
Mol Cell. 2012 Feb 10;45(3):330-43. doi: 10.1016/j.molcel.2011.11.032
Epub:
Not Epub
Abstract:
Polycomb repressive complexes (PRCs) play key roles in developmental epigenetic regulation. Yet the mechanisms that target PRCs...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yu M, Mazor T, Huang H, Huang HT, Kathrein KL, Woo AJ, Chouinard CR, Labadorf A, Akie TE, Moran TB, Xie H, Zacharek S, Taniuchi I, Roeder RG, Kim CF, Zon LI, Fraenkel E, Cantor AB. Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. Mol Cell. 2012 Feb 10;45(3):330-43. doi: 10.1016/j.molcel.2011.11.032.

Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish

Authors:
Yoo SK, Freisinger CM, LeBert DC, Huttenlocher A
Citation:
J Cell Biol. 2012;[Epub ahead of print] doi:10.1083/jcb.201203154
Epub:
Not Epub
Abstract:
Tissue injury can lead to scar formation or tissue regeneration. How regenerative animals sense initial tissue injury and...
Organism or Cell Type:
zebrafish
Citation Extract:
Yoo SK, Freisinger CM, LeBert DC, Huttenlocher A. Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish. J Cell Biol. 2012;[Epub ahead of print] doi:10.1083/jcb.201203154 .

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