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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12402 scientific papers returned from the database with the search filters currently being used below.

Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD

Authors:
McClorey G, Moulton HM, Iversen PL, Fletcher S, Wilton SD
Citation:
Gene Ther. 2006 Oct;13(19):1373-81. Epub 2006 May 25
Epub:
Not Epub
Abstract:
Manipulation of pre-mRNA splicing by antisense oligonucleotides (AOs) offers considerable potential for a number of genetic...
Delivery Method:
Bathing primary cell culture, with and without peptide conjugates
Organism or Cell Type:
cell culture: primary myoblasts, golden retreiver DMD model
Citation Extract:
McClorey G, Moulton HM, Iversen PL, Fletcher S, Wilton SD. Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD. Gene Ther. 2006 Oct;13(19):1373-81. Epub 2006 May 25.

Aryl hydrocarbon receptor activation inhibits regenerative growth

Authors:
Mathew LK, Andreasen EA, Tanguay RL
Citation:
Mol Pharmacol. 2006 Jan;69(1):257-65. Epub 2005 Oct 7.
Epub:
Not Epub
Abstract:
There is considerable literature supporting the conclusion that inappropriate activation of the aryl hydrocarbon receptor (AHR...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mathew LK, Andreasen EA, Tanguay RL. Aryl hydrocarbon receptor activation inhibits regenerative growth. Mol Pharmacol. 2006 Jan;69(1):257-65. Epub 2005 Oct 7..

Aryl Phosphate Esters Within a Major PentaBDE Replacement Product Induce Cardiotoxicity in Developing Zebrafish Embryos: Potential Role of the Aryl Hydrocarbon Receptor

Authors:
McGee SP, Konstantinov A, Stapleton HM, Volz DC
Citation:
Toxicol Sci. 2013 Feb 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Firemaster(®) 550 (FM550) is an additive flame retardant formulation of brominated and aryl phosphate ester (APE) components...
Organism or Cell Type:
zebrafish
Citation Extract:
McGee SP, Konstantinov A, Stapleton HM, Volz DC. Aryl Phosphate Esters Within a Major PentaBDE Replacement Product Induce Cardiotoxicity in Developing Zebrafish Embryos: Potential Role of the Aryl Hydrocarbon Receptor. Toxicol Sci. 2013 Feb 1. [Epub ahead of print].

Atoh1a expression must be restricted by Notch signaling for effective morphogenesis of the posterior lateral line primordium in zebrafish

Authors:
Matsuda M, Chitnis AB
Citation:
Development. 2010 Oct;137(20):3477-87
Epub:
Not Epub
Abstract:
The posterior lateral line primordium (pLLp) migrates caudally, depositing neuromasts to establish the posterior lateral line...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Matsuda M, Chitnis AB. Atoh1a expression must be restricted by Notch signaling for effective morphogenesis of the posterior lateral line primordium in zebrafish. Development. 2010 Oct;137(20):3477-87.

B7-h1 is expressed by human endothelial cells and suppresses T cell cytokine synthesis

Authors:
Mazanet MM, Hughes CC
Citation:
J Immunol. 2002 Oct 1;169(7):3581-8
Epub:
Not Epub
Abstract:
Human endothelial cells (ECs) provide costimulatory signals sufficient to activate resting memory T cells to produce IL-2 and...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture:human endothelial cells (ECs)
Citation Extract:
Mazanet MM, Hughes CC. B7-h1 is expressed by human endothelial cells and suppresses T cell cytokine synthesis. J Immunol. 2002 Oct 1;169(7):3581-8.

Backbone Modification of Nucleic Acids: Synthesis, Structure and Therapeutic Applications

Authors:
Micklefield J
Citation:
Curr Med Chem. 2001 Aug;8(10):1157-79.
Epub:
Not Epub
Abstract:
Nucleic acids have been extensively modified by replacing the phosphodiester group or the whole sugar phosphodiester with...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Micklefield J. Backbone Modification of Nucleic Acids: Synthesis, Structure and Therapeutic Applications. Curr Med Chem. 2001 Aug;8(10):1157-79..

Bbs8, together with the planar cell polarity protein Vangl2, is required to establish left-right asymmetry in zebrafish

Authors:
May-Simera HL, Kai M, Hernandez V, Osborn DP, Tada M, Beales PL
Citation:
Dev Biol. 2010 Jul 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Laterality defects such as situs inversus are not uncommonly encountered in humans, either in isolation or as part of another...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
May-Simera HL, Kai M, Hernandez V, Osborn DP, Tada M, Beales PL. Bbs8, together with the planar cell polarity protein Vangl2, is required to establish left-right asymmetry in zebrafish. Dev Biol. 2010 Jul 16. [Epub ahead of print].

C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis

Authors:
Mei J, Zhang QY, Li Z, Lin S, Gui JF
Citation:
Dev Biol. 2008 Jul 15;319(2):273-84. Epub 2008 Apr 25.
Epub:
Not Epub
Abstract:
Except for the complement C1q, the immunological functions of other C1q family members have remained unclear. Here we describe...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mei J, Zhang QY, Li Z, Lin S, Gui JF. C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis. Dev Biol. 2008 Jul 15;319(2):273-84. Epub 2008 Apr 25..

Canopy1, a positive feedback regulator of FGF signaling, controls progenitor cell clustering during Kupffer's vesicle organogenesis

Authors:
Matsui T, Thitamadee S, Murata T, Kakinuma H, Nabetani T, Hirabayashi Y, Hirate Y, Okamoto H, Bessho Y
Citation:
Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9881-6. Epub 2011 May 31
Epub:
Not Epub
Abstract:
The assembly of progenitor cells is a crucial step for organ formation during vertebrate development. Kupffer's vesicle (...
Organism or Cell Type:
zebrafish
Citation Extract:
Matsui T, Thitamadee S, Murata T, Kakinuma H, Nabetani T, Hirabayashi Y, Hirate Y, Okamoto H, Bessho Y. Canopy1, a positive feedback regulator of FGF signaling, controls progenitor cell clustering during Kupffer's vesicle organogenesis. Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9881-6. Epub 2011 May 31.

Caspy: A Zebrafish caspase activated by ASC oligomerization required for pharyngeal Arch development

Authors:
Masumoto J, Zhou W, Chen FF, Su F, Kuwada JY, Hidaka E, Katsuyama T, Sagara J, Taniguchi S, Ngo-Hazelett P, Postlethwait JH, Nunez G, Inohara N
Citation:
J Biol Chem. 2003 Feb 7;278(6):4268-76. Epub 2002 Dec 02.
Epub:
Not Epub
Abstract:
The pyrin domain was identified recently in multiple proteins that are associated with apoptosis and/or inflammation, but the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Masumoto J, Zhou W, Chen FF, Su F, Kuwada JY, Hidaka E, Katsuyama T, Sagara J, Taniguchi S, Ngo-Hazelett P, Postlethwait JH, Nunez G, Inohara N. Caspy: A Zebrafish caspase activated by ASC oligomerization required for pharyngeal Arch development. J Biol Chem. 2003 Feb 7;278(6):4268-76. Epub 2002 Dec 02..

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