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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

The homodimeric kinesin, Kif17, is essential for vertebrate photoreceptor sensory outer segment development

Authors:
Insinna C, Pathak N, Perkins B, Drummond I, Besharse JC
Citation:
Dev Biol. 2008 Apr 1;316(1):160-70. Epub 2008 Jan 31
Epub:
Not Epub
Abstract:
Sensory cilia and intraflagellar transport (IFT), a pathway essential for ciliogenesis, play important roles in embryonic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Insinna C, Pathak N, Perkins B, Drummond I, Besharse JC. The homodimeric kinesin, Kif17, is essential for vertebrate photoreceptor sensory outer segment development. Dev Biol. 2008 Apr 1;316(1):160-70. Epub 2008 Jan 31.

The impairment of HCCS leads to MLS syndrome by activating a non-canonical cell death pathway in the brain and eyes

Authors:
Indrieri A, Conte I, Chesi G, Romano A, Quartararo J, Tatè R, Ghezzi D, Zeviani M, Goffrini P, Ferrero I, Bovolenta P, Franco B
Citation:
EMBO Mol Med. 2013 Feb;5(2):280-93. doi: 10.1002/emmm.201201739. Epub 2013 Jan 22
Epub:
Not Epub
Abstract:
Mitochondrial-dependent (intrinsic) programmed cell death (PCD) is an essential homoeostatic mechanism that selects...
Delivery Method:
Microinjection
Organism or Cell Type:
medaka
Citation Extract:
Indrieri A, Conte I, Chesi G, Romano A, Quartararo J, Tatè R, Ghezzi D, Zeviani M, Goffrini P, Ferrero I, Bovolenta P, Franco B. The impairment of HCCS leads to MLS syndrome by activating a non-canonical cell death pathway in the brain and eyes. EMBO Mol Med. 2013 Feb;5(2):280-93. doi: 10.1002/emmm.201201739. Epub 2013 Jan 22.

The NPC motif of aquaporin-11, unlike the NPA motif of known aquaporins, is essential for full expression of molecular function

Authors:
Ikeda M, Andoo A, Shimono M, Takamatsu N, Taki A, Muta K, Matsushita W, Uechi T, Matsuzaki T, Kenmochi N, Takata K, Sasaki S, Ito K, Ishibashi K
Citation:
J Biol Chem. 2011 Feb 4;286(5):3342-50. Epub 2010 Nov 30
Epub:
Not Epub
Abstract:
The recently identified molecule aquaporin-11 (AQP11) has a unique amino acid sequence pattern that includes an Asn-Pro-Cys (...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ikeda M, Andoo A, Shimono M, Takamatsu N, Taki A, Muta K, Matsushita W, Uechi T, Matsuzaki T, Kenmochi N, Takata K, Sasaki S, Ito K, Ishibashi K. The NPC motif of aquaporin-11, unlike the NPA motif of known aquaporins, is essential for full expression of molecular function. J Biol Chem. 2011 Feb 4;286(5):3342-50. Epub 2010 Nov 30.

The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1

Authors:
Hwang YS, Lee HS, Kamata T, Mood K, Cho HJ, Winterbottom E, Ji YJ, Singh A, Daar IO
Citation:
Genes Dev. 2013 Mar 1;27(5):491-503. doi: 10.1101/gad.208355.112
Epub:
Not Epub
Abstract:
The formation of tissue boundaries is dependent on the cell-cell adhesion/repulsion system that is required for normal...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Hwang YS, Lee HS, Kamata T, Mood K, Cho HJ, Winterbottom E, Ji YJ, Singh A, Daar IO. The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1. Genes Dev. 2013 Mar 1;27(5):491-503. doi: 10.1101/gad.208355.112.

The Xdsg protein in presumptive primordial germ cells (pPGCs) is essential to their differentiation into PGCs in Xenopus

Authors:
Ikenishi K, Nishiumi F, Komiya T
Citation:
Dev Biol. 2006 Sep 15;297(2):483-92. Epub 2006 May 26.
Epub:
Not Epub
Abstract:
In order to know the role of the Xdsg gene in presumptive PGCs (pPGCs) of Xenopus, we attempted to inhibit the translation of...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ikenishi K, Nishiumi F, Komiya T. The Xdsg protein in presumptive primordial germ cells (pPGCs) is essential to their differentiation into PGCs in Xenopus. Dev Biol. 2006 Sep 15;297(2):483-92. Epub 2006 May 26..

Transcriptional modulation of mouse mu-opioid receptor distal promoter activity by Sox18

Authors:
Im HJ, Smirnov D, Yuhi T, Raghavan S, Olsson JE, Muscat GE, Koopman P, Loh H
Citation:
Mol Pharmacol. 2001 Jun;59(6):1486-96
Epub:
Not Epub
Abstract:
Previously, we reported the presence of dual promoters, referred to as distal (DP) and proximal, with a negative regulatory...
Delivery Method:
lipid-based
Organism or Cell Type:
cell culture: neuronal NMB and non-neuronal HeLa cells
Citation Extract:
Im HJ, Smirnov D, Yuhi T, Raghavan S, Olsson JE, Muscat GE, Koopman P, Loh H. Transcriptional modulation of mouse mu-opioid receptor distal promoter activity by Sox18. Mol Pharmacol. 2001 Jun;59(6):1486-96.

UDP-Glucose Dehydrogenase polymorphisms from patients with congenital heart valve defects disrupt enzyme stability and quaternary assembly

Authors:
Hyde AS, Farmer E, Easley KE, van Lammeren K, Christoffels VM, Barycki JJ, Bakkers J, Simpson MA
Citation:
J Biol Chem. 2012 Sep 21;287(39):32708-16. Epub 2012 Jul 18.
Epub:
Not Epub
Abstract:
Cardiac valve defects are a common congenital heart malformation and a significant clinical problem. Defining molecular factors...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hyde AS, Farmer E, Easley KE, van Lammeren K, Christoffels VM, Barycki JJ, Bakkers J, Simpson MA. UDP-Glucose Dehydrogenase polymorphisms from patients with congenital heart valve defects disrupt enzyme stability and quaternary assembly. J Biol Chem. 2012 Sep 21;287(39):32708-16. Epub 2012 Jul 18..

Vezatin, a protein associated to adherens junctions, is required for mouse blastocyst morphogenesis

Authors:
Hyenne V, Louvet-Vallee S, El-Amraoui A, Petit C, Maro B, Simmler MC
Citation:
Dev Biol. 2005 Sep 28; [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cell-cell interactions play a major role during preimplantation development of the mouse embryo. The formation of adherens...
Delivery Method:
Microinjection
Organism or Cell Type:
Mouse embryo
Citation Extract:
Hyenne V, Louvet-Vallee S, El-Amraoui A, Petit C, Maro B, Simmler MC. Vezatin, a protein associated to adherens junctions, is required for mouse blastocyst morphogenesis. Dev Biol. 2005 Sep 28; [Epub ahead of print].

XMeis3 Is Necessary for Mesodermal Hox Gene Expression and Function

Authors:
In der Rieden PMJ, Jansen HJ, Durston AJ
Citation:
PLoS ONE 2011;6(3):e18010. doi:10.1371/journal.pone.0018010
Epub:
Not Epub
Abstract:
Hox transcription factors provide positional information during patterning of the anteroposterior axis. Hox transcription...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
In der Rieden PMJ, Jansen HJ, Durston AJ. XMeis3 Is Necessary for Mesodermal Hox Gene Expression and Function. PLoS ONE 2011;6(3):e18010. doi:10.1371/journal.pone.0018010.

Zebrafish as an animal model to study ion homeostasis

Authors:
Hwang PP, Chou MY
Citation:
Pflugers Arch. 2013 Sep;465(9):1233-47. doi: 10.1007/s00424-013-1269-1. Epub 2013 Apr 9
Epub:
Not Epub
Abstract:
Zebrafish (Danio rerio) possesses several advantages as an experimental organism, including the applicability of molecular...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hwang PP, Chou MY. Zebrafish as an animal model to study ion homeostasis. Pflugers Arch. 2013 Sep;465(9):1233-47. doi: 10.1007/s00424-013-1269-1. Epub 2013 Apr 9.

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