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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target

Authors:
Wei H, Xu Y, Wang Y,Liting Xu L, Mo C, Li L, Shen B, Sun Y, Cheng P, Yang L, Pang Y, Qin A, Cao Y, Morrison SJ, Yue R
Citation:
Cell Rep. 2020;33(2):108252. doi:10.1016/j.celrep.2020.108252
Epub:
Not Epub
Abstract:
Osteogenic suppressors such as Sclerostin not only regulate skeletal development and regeneration but also serve as anti-...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(20)31241-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei H, Xu Y, Wang Y,Liting Xu L, Mo C, Li L, Shen B, Sun Y, Cheng P, Yang L, Pang Y, Qin A, Cao Y, Morrison SJ, Yue R. Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target. Cell Rep. 2020;33(2):108252. doi:10.1016/j.celrep.2020.108252.

The slc4a2b gene is required for hair cell development in zebrafish

Authors:
Qian F, Wang X, Yin Z, Xie G, Yuan H, Liu D, Chai R
Citation:
Aging. 2020;[Epub] doi:10.18632/aging.103840
Epub:
Not Epub
Abstract:
Hair cells (HCs) function as important sensory receptors that can detect movement in their immediate environment. HCs in the...
Link:
https://www.aging-us.com/article/103840/text
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Qian F, Wang X, Yin Z, Xie G, Yuan H, Liu D, Chai R. The slc4a2b gene is required for hair cell development in zebrafish. Aging. 2020;[Epub] doi:10.18632/aging.103840.

Anillin regulates epithelial cell mechanics by structuring the medial-apical actomyosin network

Authors:
Arnold TR, Shawky JH, Stephenson RE, Dinshaw KM, Higashi T, Huq F, Davidson LA, Miller AL
Citation:
Elife. 2019 Jan 31;8:e39065. doi:10.7554/eLife.39065
Epub:
Not Epub
Abstract:
Cellular forces sculpt organisms during development, while misregulation of cellular mechanics can promote disease. Here, we...
Link:
https://elifesciences.org/articles/39065
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Arnold TR, Shawky JH, Stephenson RE, Dinshaw KM, Higashi T, Huq F, Davidson LA, Miller AL. Anillin regulates epithelial cell mechanics by structuring the medial-apical actomyosin network. Elife. 2019 Jan 31;8:e39065. doi:10.7554/eLife.39065.

Whole Genome and Embryo Transcriptome Analysis of Vertebrate Identifies nxhl Controlling Angiogenesis by Targeting VE-PTP

Authors:
Luo H, Zhang Y, Ji C, Zhao Y, Peng J, Chen X, Huang Y, Liu Q, He P, Feng P, Yang C, Wei P, Yu H, Zheng H, Lin Y, Chen X
Citation:
bioRxiv. 2020;[preprint]. doi:10.1101/804609
Epub:
Not Epub
Abstract:
BACKGROUND: Angiogenesis is closely associated with angiogenesis-dependent diseases including cancers and ocular diseases. Anti...
Link:
https://www.biorxiv.org/content/10.1101/804609v3
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Luo H, Zhang Y, Ji C, Zhao Y, Peng J, Chen X, Huang Y, Liu Q, He P, Feng P, Yang C, Wei P, Yu H, Zheng H, Lin Y, Chen X. Whole Genome and Embryo Transcriptome Analysis of Vertebrate Identifies nxhl Controlling Angiogenesis by Targeting VE-PTP. bioRxiv. 2020;[preprint]. doi:10.1101/804609.

Extracellular hyaluronate pressure shaped by cellular tethers drives tissue morphogenesis

Authors:
Munjal A, Hannezo E, Mitchison TJ, Megason SG
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.09.28.316042
Epub:
Not Epub
Abstract:
How tissues acquire complex shapes is a fundamental question in biology and regenerative medicine. Zebrafish semicircular...
Link:
https://www.biorxiv.org/content/10.1101/2020.09.28.316042v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Munjal A, Hannezo E, Mitchison TJ, Megason SG. Extracellular hyaluronate pressure shaped by cellular tethers drives tissue morphogenesis. bioRxiv. 2020;[preprint] doi:10.1101/2020.09.28.316042.

Antisense oligonucleotide-based treatment of retinitis pigmentosa caused by USH2A exon 13 mutations

Authors:
Slijkerman R, van Diepen H, Dona M, Venselaar H, Zang J, Neuhauss S, Peters T, Broekman S, Pennings R, Kremer H, Adamson P, de Vrieze E, van Wijk E
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.10.06.320499
Epub:
Not Epub
Abstract:
Mutations in USH2A, encoding usherin, are the most common cause of syndromic and non-syndromic retinitis pigmentosa (RP). The...
Link:
https://www.biorxiv.org/content/10.1101/2020.10.06.320499v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Slijkerman R, van Diepen H, Dona M, Venselaar H, Zang J, Neuhauss S, Peters T, Broekman S, Pennings R, Kremer H, Adamson P, de Vrieze E, van Wijk E. Antisense oligonucleotide-based treatment of retinitis pigmentosa caused by USH2A exon 13 mutations. bioRxiv. 2020;[preprint] doi:10.1101/2020.10.06.320499 .

Kctd15 regulates nephron segment development by repressing Tfap2a activity

Authors:
Chambers BE, Clark EG, Gatz AE, Wingert RA
Citation:
Development. 2020;147:dev191973 doi:10.1242/dev.191973
Epub:
Not Epub
Abstract:
A functional vertebrate kidney relies on structural units called nephrons, which are epithelial tubules with a sequence of...
Link:
https://dev.biologists.org/content/early/2020/10/02/dev.191973
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chambers BE, Clark EG, Gatz AE, Wingert RA. Kctd15 regulates nephron segment development by repressing Tfap2a activity. Development. 2020;147:dev191973 doi:10.1242/dev.191973.

Eomesodermin is functionally conserved between zebrafish and mouse in spite of different mutant phenotypic severities, and controls left/right organiser formation via interlocking feedforward loops

Authors:
Talbot CD, Walsh MD, Cutty SJ, Elsayed R, Bruce AEE, Wardle FC, Nelson AC
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.10.02.324244
Epub:
Not Epub
Abstract:
The T-box family transcription factor Eomesodermin (Eomes) is present in all vertebrates, with many key roles in the developing...
Link:
https://www.biorxiv.org/content/10.1101/2020.10.02.324244v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Talbot CD, Walsh MD, Cutty SJ, Elsayed R, Bruce AEE, Wardle FC, Nelson AC. Eomesodermin is functionally conserved between zebrafish and mouse in spite of different mutant phenotypic severities, and controls left/right organiser formation via interlocking feedforward loops. bioRxiv. 2020;[preprint] doi:10.1101/2020.10.02.324244 .

Hcfc1b, a zebrafish ortholog of HCFC1, regulates craniofacial development by modulating mmachc expression

Authors:
Quintana AM, Geiger EA, Achilly N, Rosenblatt DS, Maclean KN, Stabler SP, Artinger KB, Appel B, Shaikh TH
Citation:
Dev Biol. 2014 Dec 1;396(1):94-106. doi: 10.1016/j.ydbio.2014.09.026. Epub 2014 Oct 2
Epub:
Not Epub
Abstract:
Mutations in HCFC1 (MIM300019), have been recently associated with cblX (MIM309541), an X-linked, recessive disorder...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160614004953
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Quintana AM, Geiger EA, Achilly N, Rosenblatt DS, Maclean KN, Stabler SP, Artinger KB, Appel B, Shaikh TH. Hcfc1b, a zebrafish ortholog of HCFC1, regulates craniofacial development by modulating mmachc expression. Dev Biol. 2014 Dec 1;396(1):94-106. doi: 10.1016/j.ydbio.2014.09.026. Epub 2014 Oct 2.

Caveolin 1 is required for axonal outgrowth of motor neurons and affects Xenopus neuromuscular development

Authors:
Breuer M, Berger H, Borchers A
Citation:
Sci Rep. 2020 Oct 5;10(1):16446. doi: 10.1038/s41598-020-73429-x
Epub:
Not Epub
Abstract:
Caveolins are essential structural proteins driving the formation of caveolae, specialized invaginations of the plasma membrane...
Link:
https://www.nature.com/articles/s41598-020-73429-x
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Breuer M, Berger H, Borchers A. Caveolin 1 is required for axonal outgrowth of motor neurons and affects Xenopus neuromuscular development. Sci Rep. 2020 Oct 5;10(1):16446. doi: 10.1038/s41598-020-73429-x.

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