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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Biallelic variants in PSMB1 encoding the proteasome subunit β6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature
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Citation:
Hum Molec Genet. 2020;[Epub] doi:10.1093/hmg/ddaa032 Epub:
Yes Abstract:
The molecular cause of the majority of rare autosomal recessive disorders remains unknown. Consanguinity due to extensive... Organism or Cell Type:
zebrafish Citation Extract: Ansar M, Ebstein F, Özkoç H, Paracha SA, Iwaszkiewicz J, Gesemann M, Zoete V, Ranza E, Santoni FA, Sarwar MT, Ahmed J, Krüger E, Bachmann-Gagescu R, Antonarakis SE. Biallelic variants in PSMB1 encoding the proteasome subunit β6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature. Hum Molec Genet. 2020;[Epub] doi:10.1093/hmg/ddaa032. |
Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis
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Citation:
Cell Rep. 2020;30(9):2879-88. doi:10.1016/j.celrep.2020.02.024 Epub:
Not Epub Abstract:
Peristalsis is indispensable for physiological function of the gut. The enteric nervous system (ENS) plays an important role in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fujii K, Nakajo K, Egashira Y, Yamamoto Y, Kitada K, Taniguchi K, Kawai M, Tomiyama H, Kawakami K, Uchiyama K, Ono F. Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis. Cell Rep. 2020;30(9):2879-88. doi:10.1016/j.celrep.2020.02.024. |
Amelioration of Large Bile Duct Damage by Histamine-2 Receptor Vivo-Morpholino Treatment
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Citation:
Am J Pathol. 2020;190( 5):1018–29 doi:10.1016/j.ajpath.2020.01.013 Epub:
Not Epub Abstract:
Histamine binds to one of the four G-protein–coupled receptors expressed by large cholangiocytes. Histamine specifically... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Kennedy L, Meadows V, Kyritsi K, Pham L, Kundu D, Kulkarni R, Cerritos K, Demieville J, Hargrove L, Glaser S, Zhou T, Jaeger V, Alpini G, Francis H. Amelioration of Large Bile Duct Damage by Histamine-2 Receptor Vivo-Morpholino Treatment. Am J Pathol. 2020;190( 5):1018–29 doi:10.1016/j.ajpath.2020.01.013. |
Genome-wide molecular effects of the neuropsychiatric 16p11 CNVs in an iPSC-to-iN neuronal model
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.09.940965 Epub:
Not Epub Abstract:
Copy number variants (CNVs), either deletions or duplications, at the 16p11.2 locus in the human genome are known to increase... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ward TR, Zhang X, Louis C. Leung, Zhou B, Muench K, Roth JG, Khechaduri A, Plastini MJ, Charlton C, Pattni R, Ho S, Ho M, Huang Y, Hallmayer JF, Mourrain P, Palmer TD, Urban AE. Genome-wide molecular effects of the neuropsychiatric 16p11 CNVs in an iPSC-to-iN neuronal model. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.09.940965 . |
Transcriptome profiling of the branchial arches reveals cell type composition and a conserved signature of neural crest cell invasion
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.28.969915 Epub:
Not Epub Abstract:
The vertebrate branchial arches that give rise to structures of the head, neck, and heart form with very dynamic tissue growth... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Morrison JA, McLennan R, Teddy JM, Scott AR, Kasemeier-Kulesa K-K, Gogol MM, Kulesa PM. Transcriptome profiling of the branchial arches reveals cell type composition and a conserved signature of neural crest cell invasion. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.28.969915 . |
Prmt5 promotes vascular morphogenesis in zebrafish independently of its methyltransferase activity
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Citation:
BioRxiv. 2020;[preprint] doi:10.1101/2020.02.27.967810 Epub:
Not Epub Abstract:
In vertebrate, blood cell formation is tightly associated with the development of the vascular system. While the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Quillien A, Boulet M, Ethuin S, Vandel L. Prmt5 promotes vascular morphogenesis in zebrafish independently of its methyltransferase activity. BioRxiv. 2020;[preprint] doi:10.1101/2020.02.27.967810. |
Zebrafish miR-462-731 is required for digestive organs development
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Citation:
Comp Biochem Physiol Part D Genomics Proteomics. 2020 Feb 29;34:100679. doi: 10.1016/j.cbd.2020.100679. [Epub ahead of print] Epub:
Not Epub Abstract:
With-no-lysine (K)-1 (WNK1) is the founding member of family of four protein kinases with atypical placement of catalytic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Huang Y, Huang C-X, Wang W-F, Liu H, Wang H-L. Zebrafish miR-462-731 is required for digestive organs development. Comp Biochem Physiol Part D Genomics Proteomics. 2020 Feb 29;34:100679. doi: 10.1016/j.cbd.2020.100679. [Epub ahead of print]. |
WNK1 Kinase Stimulates Angiogenesis to Promote Tumor Growth and Metastasis
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Citation:
Cancers. 2020;12(3):[Epub] doi:0.3390/cancers12030575 Epub:
Not Epub Abstract:
With-no-lysine (K)-1 (WNK1) is the founding member of family of four protein kinases with atypical placement of catalytic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sie Z-L, Li R-Y, Sampurna PB, Hsu P-J, Liu S-C, Wang H-D, Huang C-L, Yuh C-H. WNK1 Kinase Stimulates Angiogenesis to Promote Tumor Growth and Metastasis. Cancers. 2020;12(3):[Epub] doi:0.3390/cancers12030575. |
Aberrant Expression of a Non-muscle RBFOX2 Isoform Triggers Cardiac Conduction Defects in Myotonic Dystrophy
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Citation:
Dev Cell. 2020;[Epub ahead of print] doi:10.1016/j.devcel.2020.01.037 Epub:
Yes Abstract:
Myotonic dystrophy type 1 (DM1) is a multisystemic genetic disorder caused by the CTG repeat expansion in the 3′-untranslated... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HL-1 Citation Extract: Misra C, Bangru S, Lin F, Lam K, Koenig SN, Lubbers ER, Hedhli J, Murphy NP, Parker DJ, Dobrucki LW, Cooper TA, Tajkhorshid E, Mohler PJ, Kalsotra A. Aberrant Expression of a Non-muscle RBFOX2 Isoform Triggers Cardiac Conduction Defects in Myotonic Dystrophy. Dev Cell. 2020;[Epub ahead of print] doi:10.1016/j.devcel.2020.01.037. |
Deciphering and modelling the TGF-β signalling interplays specifying the dorsal-ventral axis of the sea urchin embryo
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.26.966556 Epub:
Not Epub Abstract:
During sea urchin development, secretion of Nodal and BMP2/4 ligands and their antagonists Lefty and Chordin from a ventral... Delivery Method:
microinjection Organism or Cell Type:
Paracentrotus lividus (sea urchin) Citation Extract: Floc'hlay S, Jimenez MDM, Hernandez C, Haillot E, Thomas-Chollier M, Lepage T, Thieffry D. Deciphering and modelling the TGF-β signalling interplays specifying the dorsal-ventral axis of the sea urchin embryo. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.26.966556. |