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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
The combination of loss of glyoxalase1 and obesity results in hyperglycemia
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Citation:
JCI Insight. 2019 Jun 20;4(12). pii: 126154. doi: 10.1172/jci.insight.126154. eCollection 2019 Jun 20 Epub:
Not Epub Abstract:
The increased formation of methylglyoxal (MG) under hyperglycemia is associated with the development of microvascular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lodd E, Wiggenhauser LM, Morgenstern J, Fleming TH, Poschet G, Büttner M, Tabler CT, Wohlfart DP, Nawroth PP, Kroll J. The combination of loss of glyoxalase1 and obesity results in hyperglycemia. JCI Insight. 2019 Jun 20;4(12). pii: 126154. doi: 10.1172/jci.insight.126154. eCollection 2019 Jun 20. |
Connexin 43 impacts the chick premigratory cranial neural crest cell population without affecting the neural crest cell epithelial-to-mesenchymal transition
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/673921 Epub:
Not Epub Abstract:
Gap junctions are intercellular channels that allow for the diffusion of small ions and solutes between coupled cells. Connexin... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Jourdeuil K, Taneyhill LA. Connexin 43 impacts the chick premigratory cranial neural crest cell population without affecting the neural crest cell epithelial-to-mesenchymal transition. bioRxiv. 2019;[preprint] doi:10.1101/673921 . |
Direct Reprogramming of Human DMD Fibroblasts into Myotubes for In Vitro Evaluation of Antisense-Mediated Exon Skipping and Exons 45-55 Skipping Accompanied by Rescue of Dystrophin Expression
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Citation:
Methods Mol Biol. 2018;1828:141-150. doi: 10.1007/978-1-4939-8651-4_8 Epub:
Not Epub Abstract:
Antisense oligonucleotide-mediated exon skipping is a promising therapeutic approach for the treatment of various genetic... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: primary human fibroblasts (DMD) Citation Extract: Lee JJA, Saito T, Duddy W, Takeda S, Yokota T. Direct Reprogramming of Human DMD Fibroblasts into Myotubes for In Vitro Evaluation of Antisense-Mediated Exon Skipping and Exons 45-55 Skipping Accompanied by Rescue of Dystrophin Expression. Methods Mol Biol. 2018;1828:141-150. doi: 10.1007/978-1-4939-8651-4_8. |
Stop-gain mutations in UBAP1 cause pure autosomal-dominant spastic paraplegia
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Citation:
Brain. 2019 Jun 15. pii: awz158. doi: 10.1093/brain/awz158. [Epub ahead of print] Epub:
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Hereditary spastic paraplegias refer to a heterogeneous group of neurodegenerative disorders resulting from degeneration of the... Organism or Cell Type:
zebrafish Citation Extract: Lin X, Su HZ, Dong EL, Lin XH, Zhao M, Yang C, Wang C, Wang J, Chen YJ, Yu H, Xu J, Ma LX, Xiong ZQ, Wang N, Chen WJ. Stop-gain mutations in UBAP1 cause pure autosomal-dominant spastic paraplegia. Brain. 2019 Jun 15. pii: awz158. doi: 10.1093/brain/awz158. [Epub ahead of print]. |
Zebrafish macroH2A variants have distinct embryo localization and function
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Citation:
Sci Rep. 2019 Jun 14;9(1):8632. doi: 10.1038/s41598-019-45058-6 Epub:
Not Epub Abstract:
Mouse and cell-based studies have shown that macroH2A histone variants predominantly associate with heterochromatin. Functional... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gonzalez-Munoz E, Arboleda-Estudillo Y, Chanumolu SK, Otu HH, Cibelli JB. Zebrafish macroH2A variants have distinct embryo localization and function. Sci Rep. 2019 Jun 14;9(1):8632. doi: 10.1038/s41598-019-45058-6. |
β6 integrinosis: a new lethal autosomal recessive ITGB6 disorder leading to impaired conformational transitions of the αVβ6 integrin receptor
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Citation:
Gut. 2019;[Epub ahead of print] doi:10.1136/gutjnl-2019-319015 Epub:
Yes Abstract:
[no abstract available] Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Weil P, van den Bruck R, Ziegenhals T, Juranek S, Goedde D, Orth V, Wirth S, Jenke AC, Postberg J. β6 integrinosis: a new lethal autosomal recessive ITGB6 disorder leading to impaired conformational transitions of the αVβ6 integrin receptor. Gut. 2019;[Epub ahead of print] doi:10.1136/gutjnl-2019-319015 . |
A mesoderm-independent role for Nodal signaling in convergence & extension gastrulation movements
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/671164 Epub:
Not Epub Abstract:
During embryogenesis, the distinct morphogenetic cell behavior programs that shape tissues are influenced both by the fate of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Williams MLK, Solnica-Krezel L. A mesoderm-independent role for Nodal signaling in convergence & extension gastrulation movements. bioRxiv. 2019;[preprint] doi:10.1101/671164. |
The Spatiotemporal Control of Zygotic Genome Activation
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Citation:
iScience. 2019 Jun 11;16:485-498. doi: 10.1016/j.isci.2019.06.013. [Epub ahead of print] Epub:
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One of the earliest and most significant events in embryonic development is zygotic genome activation (ZGA). In several species... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Gentsch GE, Owens NDL, Smith JC. The Spatiotemporal Control of Zygotic Genome Activation. iScience. 2019 Jun 11;16:485-498. doi: 10.1016/j.isci.2019.06.013. [Epub ahead of print]. |
The identification of mecciRNAs and their roles in mitochondrial entry of proteins
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/668665 Epub:
Not Epub Abstract:
Mammalian mitochondria have small genomes encoding very limited numbers of proteins. Over one thousand proteins and noncoding... Delivery Method:
electroporation Organism or Cell Type:
cell culture: 293T Citation Extract: Liu X, Wang X, Li J, Hu S, Deng Y, Yin H, Bao X, Zhang QC, Wang G, Wang B, Shi Q, Shan G. The identification of mecciRNAs and their roles in mitochondrial entry of proteins. bioRxiv. 2019;[preprint] doi:10.1101/668665. |
The nuclear pore proteins Nup88/214 and T-ALL-associated NUP214 fusion proteins regulate Notch signaling
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Citation:
J Biol Chem. 2019 Jun 11. pii: jbc.RA118.006357. doi: 10.1074/jbc.RA118.006357. [Epub ahead of print] Epub:
Yes Abstract:
The Notch receptor is a key mediator of developmental programs and cell-fate decisions. Imbalanced Notch signaling leads to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kindermann B, Valkova C, Krämer A, Perner B, Engelmann C, Behrendt L, Kritsch D, Jungnickel B, Kehlenbach RH, Oswald F, Englert C, Kaether C. The nuclear pore proteins Nup88/214 and T-ALL-associated NUP214 fusion proteins regulate Notch signaling. J Biol Chem. 2019 Jun 11. pii: jbc.RA118.006357. doi: 10.1074/jbc.RA118.006357. [Epub ahead of print]. |