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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration

Authors:
Wei L, Blader P, Roussigné M
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/570820
Epub:
Not Epub
Abstract:
Coordinated migration of cell collectives is important during embryonic development and relies on cells integrating multiple...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei L, Blader P, Roussigné M. Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration. bioRxiv. 2019;[preprint] doi:10.1101/570820.

Developmentally regulated tcf7l2 splice variants mediate transcriptional repressor functions during eye formation

Authors:
Young RM, Ewan KB, Ferrer VP, Allende ML, Dale TC, Wilson SW
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/607713
Epub:
Not Epub
Abstract:
Tcf7l2 mediates Wnt/β-Catenin signalling during development and is implicated in cancer and type-2 diabetes. The mechanisms by...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Young RM, Ewan KB, Ferrer VP, Allende ML, Dale TC, Wilson SW. Developmentally regulated tcf7l2 splice variants mediate transcriptional repressor functions during eye formation. bioRxiv. 2019;[preprint] doi:10.1101/607713 .

miR‐181a/b downregulation exerts a protective action on mitochondrial disease models

Authors:
Indrieri A, Carrella S, Romano A, Spaziano A, Marrocco E, Fernandez‐Vizarra E, Barbato S, Pizzo M, Ezhova Y, Golia FM, Ciampi L, Tammaro R, Henao‐Mejia J, Williams A, Flavell RA, De Leonibus E, Zeviani M, Surace EM, Banfi S, Franco B
Citation:
EMBO Molec Med. 2019;e8734 [Epub ahead of print] doi:10.15252/emmm.201708734
Epub:
Yes
Abstract:
Mitochondrial diseases (MDs) are a heterogeneous group of devastating and often fatal disorders due to defective oxidative...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Indrieri A, Carrella S, Romano A, Spaziano A, Marrocco E, Fernandez‐Vizarra E, Barbato S, Pizzo M, Ezhova Y, Golia FM, Ciampi L, Tammaro R, Henao‐Mejia J, Williams A, Flavell RA, De Leonibus E, Zeviani M, Surace EM, Banfi S, Franco B. miR‐181a/b downregulation exerts a protective action on mitochondrial disease models. EMBO Molec Med. 2019;e8734 [Epub ahead of print] doi:10.15252/emmm.201708734.

In Ovo Electroporation of Plasmid DNA and Morpholinos into Specific Tissues During Early Embryogenesis

Authors:
McLennan R, Kulesa PM
Citation:
Neural Crest Cells. 2019. Methods in Molecular Biology (1976):71-82 Springer New York, New York, NY. doi:10.1007/978-1-4939-9412-0_6
Epub:
Not Epub
Abstract:
In ovo electroporation enables transfection of non-viral plasmid DNA and/or morpholinos to fluorescently label and/or perturb...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
McLennan R, Kulesa PM. In Ovo Electroporation of Plasmid DNA and Morpholinos into Specific Tissues During Early Embryogenesis. Neural Crest Cells. 2019. Methods in Molecular Biology (1976):71-82 Springer New York, New York, NY. doi:10.1007/978-1-4939-9412-0_6.

Neutrophils use selective autophagy receptor p62 to target Staphylococcus aureus for degradation in the zebrafish model

Authors:
Gibson JF, Prajsnar TK, Serba JJ, Tonge RD, Grierson AJ, Ingham PW, Renshaw SA, Johnston SA
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/604884
Epub:
Not Epub
Abstract:
Autophagy leads to degradation of cellular components, and has an important role in destroying intracellular pathogens....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gibson JF, Prajsnar TK, Serba JJ, Tonge RD, Grierson AJ, Ingham PW, Renshaw SA, Johnston SA . Neutrophils use selective autophagy receptor p62 to target Staphylococcus aureus for degradation in the zebrafish model. bioRxiv. 2019;[preprint] doi:10.1101/604884 .

Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation

Authors:
Ando H, Sato T, Ito T, Yamamoto J, Sakamoto S, Nitta N, Asatsuma-Okumura T, Shimizu N, Mizushima R, Aoki I, Imai T, Yamaguchi Y, Berk AJ, Handa H
Citation:
iScience. 2019;[Epub ahead of print] doi:10.1016/j.isci.2019.04.007
Epub:
Yes
Abstract:
Thalidomide is a teratogen that causes multiple malformations in the developing baby through its interaction with Cereblon (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ando H, Sato T, Ito T, Yamamoto J, Sakamoto S, Nitta N, Asatsuma-Okumura T, Shimizu N, Mizushima R, Aoki I, Imai T, Yamaguchi Y, Berk AJ, Handa H . Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation. iScience. 2019;[Epub ahead of print] doi:10.1016/j.isci.2019.04.007.

A High-Throughput Assay for Congenital and Age-Related Eye Diseases in Zebrafish

Authors:
Brastrom LK, Scott CA, Dawson DV, Slusarski DC
Citation:
Biomedicines. 2019;7(2):28 doi:10.3390/biomedicines7020028
Epub:
Not Epub
Abstract:
Debilitating visual impairment caused by cataracts or microphthalmia is estimated to affect roughly 20 million people in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brastrom LK, Scott CA, Dawson DV, Slusarski DC. A High-Throughput Assay for Congenital and Age-Related Eye Diseases in Zebrafish. Biomedicines. 2019;7(2):28 doi:10.3390/biomedicines7020028.

ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer

Authors:
Daulat AM, Finetti P, Revinski D, Wagner MS, Camoin L, Audebert S, Birnbaum D, Kodjabachian L, Borg J-P, Bertucci F
Citation:
Brit J Cancer. 2019;[Epub ahead of print] doi:doi.org/10.1038/s41416-019-0448-z
Epub:
Yes
Abstract:
Background: Triple-negative breast cancers (TNBC) are poor-prognosis tumours candidate to chemotherapy as only systemic...
Organism or Cell Type:
Xenopus
Citation Extract:
Daulat AM, Finetti P, Revinski D, Wagner MS, Camoin L, Audebert S, Birnbaum D, Kodjabachian L, Borg J-P, Bertucci F. ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer. Brit J Cancer. 2019;[Epub ahead of print] doi:doi.org/10.1038/s41416-019-0448-z.

Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation

Authors:
Hsu JJ, Vedula V, Baek KI, Chen C, Chen J, Chou MI, Lam J, Subhedar S, Wang J, Ding Y, Chang C-C, Lee J, Demer LL, Tintut Y, Marsden AL, Hsiai TK
Citation:
JCI Insight. 2019;[in-press preview] doi:10.1172/jci.insight.124460
Epub:
Yes
Abstract:
Biomechanical forces and endothelial-to-mesenchymal transition (EndoMT) are known to mediate valvulogenesis. However, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hsu JJ, Vedula V, Baek KI, Chen C, Chen J, Chou MI, Lam J, Subhedar S, Wang J, Ding Y, Chang C-C, Lee J, Demer LL, Tintut Y, Marsden AL, Hsiai TK. Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation. JCI Insight. 2019;[in-press preview] doi:10.1172/jci.insight.124460.

The voltage sensing phosphatase (VSP) localizes to the apical membrane of kidney tubule epithelial cells

Authors:
Ratzan W, Rayaprolu V, Killian SE, Bradley R, Kohout SC
Citation:
PLoS ONE. 2019;14(4):e0209056. doi:10.1371/journal.pone.0209056
Epub:
Not Epub
Abstract:
Voltage-sensing phosphatases (VSPs) are transmembrane proteins that couple changes in membrane potential to hydrolysis of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ratzan W, Rayaprolu V, Killian SE, Bradley R, Kohout SC. The voltage sensing phosphatase (VSP) localizes to the apical membrane of kidney tubule epithelial cells. PLoS ONE. 2019;14(4):e0209056. doi:10.1371/journal.pone.0209056.

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