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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Phage therapy against Pseudomonas aeruginosa infections in a cystic fibrosis zebrafish model

Authors:
Cafora M, Deflorian G, Forti F, Ferrari L, Binelli G, Briani F, Ghisotti D, Pistocchi A
Citation:
Sci Rep. 2019 Feb 6;9(1):1527. doi: 10.1038/s41598-018-37636-x
Epub:
Not Epub
Abstract:
Cystic fibrosis (CF) is a hereditary disease due to mutations in the CFTR gene and causes mortality in humans mainly due to...
Link:
https://www.nature.com/articles/s41598-018-37636-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cafora M, Deflorian G, Forti F, Ferrari L, Binelli G, Briani F, Ghisotti D, Pistocchi A. Phage therapy against Pseudomonas aeruginosa infections in a cystic fibrosis zebrafish model. Sci Rep. 2019 Feb 6;9(1):1527. doi: 10.1038/s41598-018-37636-x.

Dynamin binding protein is required for Xenopus laevis kidney development

Authors:
DeLay BD, Baldwin TA, Miller RK
Citation:
Front Physiol. 2019;[Epub ahead of print] doi:10.3389/fphys.2019.00143
Epub:
Yes
Abstract:
The adult human kidney contains over one million nephrons, with each nephron consisting of a tube containing segments that have...
Link:
https://www.frontiersin.org/articles/10.3389/fphys.2019.00143/abstract
Organism or Cell Type:
Xenopus laevis
Citation Extract:
DeLay BD, Baldwin TA, Miller RK. Dynamin binding protein is required for Xenopus laevis kidney development. Front Physiol. 2019;[Epub ahead of print] doi:10.3389/fphys.2019.00143.

Aneuploidy in Oocytes Is Prevented by Sustained CDK1 Activity through Degron Masking in CyclinB1

Authors:
Levasseur MD, Thomas C, Davies OR, Higgins JMG, Madgwick S
Citation:
Dev Cell. 2019;[Epub ahead of print] doi:10.1016/j.devcel.2019.01.008
Epub:
Yes
Abstract:
Successful mitosis requires that cyclin B1:CDK1 ki-nase activity remains high until chromosomes arecorrectly aligned on the...
Link:
https://www.sciencedirect.com/science/article/pii/S1534580719300085
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Levasseur MD, Thomas C, Davies OR, Higgins JMG, Madgwick S. Aneuploidy in Oocytes Is Prevented by Sustained CDK1 Activity through Degron Masking in CyclinB1. Dev Cell. 2019;[Epub ahead of print] doi:10.1016/j.devcel.2019.01.008.

Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish

Authors:
Huo X, Li H, Li Z, Yan C, Agrawal I, Mathavan S, Liu J, Gong Z
Citation:
Sci Rep. 2019 Feb 6;9(1):1509. doi: 10.1038/s41598-018-36605-8
Epub:
Not Epub
Abstract:
We have previously demonstrated the pro-tumoral role of neutrophils using a kras-induced zebrafish hepatocarcinogenesis model....
Link:
https://www.nature.com/articles/s41598-018-36605-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huo X, Li H, Li Z, Yan C, Agrawal I, Mathavan S, Liu J, Gong Z. Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish. Sci Rep. 2019 Feb 6;9(1):1509. doi: 10.1038/s41598-018-36605-8.

Mutation of microphthalmia-associated transcription factor (mitf) in zebrafish sensitizes for glomerulopathy

Authors:
Müller-Deile J, Schenk H, Niggemann P, Bolaños-Palmieri P, Teng B, Higgs A, Staggs L, Haller H, Schroder P, Schiffer M
Citation:
Biol Open. 2019 Feb 4. pii: bio.040253. doi: 10.1242/bio.040253. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Different glomerular diseases that affect podocyte homeostasis can clinically present as nephrotic syndrome with massive...
Link:
http://bio.biologists.org/content/early/2019/01/30/bio.040253.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Müller-Deile J, Schenk H, Niggemann P, Bolaños-Palmieri P, Teng B, Higgs A, Staggs L, Haller H, Schroder P, Schiffer M. Mutation of microphthalmia-associated transcription factor (mitf) in zebrafish sensitizes for glomerulopathy. Biol Open. 2019 Feb 4. pii: bio.040253. doi: 10.1242/bio.040253. [Epub ahead of print].

Production of Germ-Line Chimeras in Zebrafish

Authors:
Saito T, Goto R, Rivers N, Yamaha E
Citation:
Methods Mol Biol. 2019;1920:327-341. doi: 10.1007/978-1-4939-9009-2_20
Epub:
Not Epub
Abstract:
The induction of germ-line chimerism in fish is a strategy for the reproduction of endangered or genetically valuable fish...
Link:
https://link.springer.com/protocol/10.1007%2F978-1-4939-9009-2_20
Organism or Cell Type:
zebrafish
Citation Extract:
Saito T, Goto R, Rivers N, Yamaha E. Production of Germ-Line Chimeras in Zebrafish. Methods Mol Biol. 2019;1920:327-341. doi: 10.1007/978-1-4939-9009-2_20.

Embryological and Genetic Manipulation of Chick Development

Authors:
Gammill LS, Jacques-Fricke B, Roffers-Agarwal J
Citation:
Methods Mol Biol. 2019;1920:75-97. doi: 10.1007/978-1-4939-9009-2_6
Epub:
Not Epub
Abstract:
The ability to combine embryological manipulations with gene function analysis in an amniote embryo makes the chick a valuable...
Link:
https://link.springer.com/protocol/10.1007%2F978-1-4939-9009-2_6
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Gammill LS, Jacques-Fricke B, Roffers-Agarwal J. Embryological and Genetic Manipulation of Chick Development. Methods Mol Biol. 2019;1920:75-97. doi: 10.1007/978-1-4939-9009-2_6.

Transcriptome profiling of zebrafish optic fissure fusion

Authors:
Richardson R, Owen N, Toms M, Young RM, Tracey-White D, Moosajee M
Citation:
Sci Rep. 2019 Feb 7;9(1):1541. doi: 10.1038/s41598-018-38379-5
Epub:
Not Epub
Abstract:
Incomplete fusion of the optic fissure leads to ocular coloboma, a congenital eye defect that affects up to 7.5 per 10,000...
Link:
https://www.nature.com/articles/s41598-018-38379-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Richardson R, Owen N, Toms M, Young RM, Tracey-White D, Moosajee M. Transcriptome profiling of zebrafish optic fissure fusion. Sci Rep. 2019 Feb 7;9(1):1541. doi: 10.1038/s41598-018-38379-5.

The regulatory pathway from genes directly activated by maternal factors to muscle structural genes in ascidian embryos

Authors:
Yu D, Oda-Ishii I, Kubo A, Satou Y
Citation:
Development. 2019 Jan 23. pii: dev.173104. doi: 10.1242/dev.173104. [Epub ahead of print]
Epub:
Yes
Abstract:
Striated muscle cells in the tail of ascidian tadpole larvae differentiate cell-autonomously. Although several key regulatory...
Link:
http://dev.biologists.org/content/146/3/dev173104
Delivery Method:
microinjection
Organism or Cell Type:
ascidian
Citation Extract:
Yu D, Oda-Ishii I, Kubo A, Satou Y. The regulatory pathway from genes directly activated by maternal factors to muscle structural genes in ascidian embryos. Development. 2019 Jan 23. pii: dev.173104. doi: 10.1242/dev.173104. [Epub ahead of print].

A genetic model of CEDNIK syndrome in zebrafish highlights the role of the SNARE protein Snap29 in neuromotor and epidermal development

Authors:
Mastrodonato V, Beznoussenko G, Mironov A, Ferrari L, Deflorian G, Vaccari T
Citation:
Sci Rep. 2019:1211. doi:10.1038/s41598-018-37780-4
Epub:
Not Epub
Abstract:
Homozygous mutations in SNAP29, encoding a SNARE protein mainly involved in membrane fusion, cause CEDNIK (Cerebral Dysgenesis...
Link:
https://www.nature.com/articles/s41598-018-37780-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mastrodonato V, Beznoussenko G, Mironov A, Ferrari L, Deflorian G, Vaccari T. A genetic model of CEDNIK syndrome in zebrafish highlights the role of the SNARE protein Snap29 in neuromotor and epidermal development. Sci Rep. 2019:1211. doi:10.1038/s41598-018-37780-4.

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