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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Mutations in the zebrafish hmgcs1 gene reveal a novel function for isoprenoids during red blood cell development

Authors:
Hernandez JA, Castro VL, Reyes-Nava N, Montes LP, Quintana AM
Citation:
bioRxiv. 2018:[Preprint] doi:10.1101/508531
Epub:
Not Epub
Abstract:
Erythropoiesis is the process by which new red blood cells (RBCs) are formed and defects in this process can lead to anemia or...
Link:
https://www.biorxiv.org/content/early/2018/12/30/508531
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hernandez JA, Castro VL, Reyes-Nava N, Montes LP, Quintana AM. Mutations in the zebrafish hmgcs1 gene reveal a novel function for isoprenoids during red blood cell development. bioRxiv. 2018:[Preprint] doi:10.1101/508531.

Neurite Collapse and Altered ER Ca2+ Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation

Authors:
Korecka JA, Talbot S, Osborn TM, de Leeuw SM, Levy SA, Ferrari EJ, Moskites A, Atkinson E, Jodelka FM, Hinrich AJ, Hastings ML, Woolf CJ, Hallett PJ, Isacson O
Citation:
Stem Cell Reports. 2018 Dec 14. pii: S2213-6711(18)30490-9. doi: 10.1016/j.stemcr.2018.11.021. [Epub ahead of print]
Epub:
Yes
Abstract:
The Parkinson disease (PD) genetic LRRK2 gain-of-function mutations may relate to the ER pathological changes seen in PD...
Link:
https://www.sciencedirect.com/science/article/pii/S2213671118304909
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human Parkinson's Disease iPSC-derived neurons
Citation Extract:
Korecka JA, Talbot S, Osborn TM, de Leeuw SM, Levy SA, Ferrari EJ, Moskites A, Atkinson E, Jodelka FM, Hinrich AJ, Hastings ML, Woolf CJ, Hallett PJ, Isacson O. Neurite Collapse and Altered ER Ca2+ Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation. Stem Cell Reports. 2018 Dec 14. pii: S2213-6711(18)30490-9. doi: 10.1016/j.stemcr.2018.11.021. [Epub ahead of print].

FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence

Authors:
Latorre E, Ostler EL, Faragher RGA, Harries LW
Citation:
FASEB J. 2019 Jan;33(1):1086-1097. doi: 10.1096/fj.201801154R. Epub 2018 Aug 8
Epub:
Not Epub
Abstract:
Cellular plasticity is a key facet of cellular homeostasis requiring correct temporal and spatial patterns of alternative...
Link:
https://www.fasebj.org/doi/abs/10.1096/fj.201801154R
Organism or Cell Type:
cell culture: senescent primary human fibroblasts
Citation Extract:
Latorre E, Ostler EL, Faragher RGA, Harries LW. FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence. FASEB J. 2019 Jan;33(1):1086-1097. doi: 10.1096/fj.201801154R. Epub 2018 Aug 8.

Blastemal progenitors modulate immune signaling during early limb regeneration

Authors:
Tsai SL, Baselga-Garriga C, Melton DA
Citation:
Development. 2019 Jan 2;146(1). pii: dev169128. doi: 10.1242/dev.169128
Epub:
Not Epub
Abstract:
Blastema formation, a hallmark of limb regeneration, requires proliferation and migration of progenitors to the amputation...
Link:
http://dev.biologists.org/content/146/1/dev169128.long
Delivery Method:
injection
Organism or Cell Type:
Ambystoma mexicanum (axolotl)
Citation Extract:
Tsai SL, Baselga-Garriga C, Melton DA. Blastemal progenitors modulate immune signaling during early limb regeneration. Development. 2019 Jan 2;146(1). pii: dev169128. doi: 10.1242/dev.169128.

Mutations in NCAPG2 Cause a Severe Neurodevelopmental Syndrome that Expands the Phenotypic Spectrum of Condensinopathies

Authors:
Khan TN, Khan K, Sadeghpour A, Reynolds H, Perilla Y, McDonald MT, Gallentine WB, Baig SM; Task Force for Neonatal Genomics, Davis EE, Katsanis N
Citation:
Am J Hum Genet. 2019 Jan 3;104(1):94-111. doi: 10.1016/j.ajhg.2018.11.017
Epub:
Not Epub
Abstract:
The use of whole-exome and whole-genome sequencing has been a catalyst for a genotype-first approach to diagnostics. Under this...
Link:
https://www.cell.com/ajhg/fulltext/S0002-9297(18)30425-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Khan TN, Khan K, Sadeghpour A, Reynolds H, Perilla Y, McDonald MT, Gallentine WB, Baig SM; Task Force for Neonatal Genomics, Davis EE, Katsanis N. Mutations in NCAPG2 Cause a Severe Neurodevelopmental Syndrome that Expands the Phenotypic Spectrum of Condensinopathies. Am J Hum Genet. 2019 Jan 3;104(1):94-111. doi: 10.1016/j.ajhg.2018.11.017.

Zebrafish microRNA miR-210-5p inhibits primitive myelopoiesis by silencing foxj1b and slc3a2a mRNAs downstream of gata4/5/6 transcription factor genes

Authors:
Jia W, Liang D, Li N, Liu M, Dong Z, Li J, Dong X, Yue Y, Hu P, Yao J, Zhao Q
Citation:
J Biol Chem. 2018 Dec 28. pii: jbc.RA118.005079. doi: 10.1074/jbc.RA118.005079. [Epub ahead of print]
Epub:
Yes
Abstract:
Zebrafish gata4/5/6 genes encode transcription factors that lie on the apex of the regulatory hierarchy in primitive...
Link:
http://www.jbc.org/content/early/2018/12/28/jbc.RA118.005079.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jia W, Liang D, Li N, Liu M, Dong Z, Li J, Dong X, Yue Y, Hu P, Yao J, Zhao Q. Zebrafish microRNA miR-210-5p inhibits primitive myelopoiesis by silencing foxj1b and slc3a2a mRNAs downstream of gata4/5/6 transcription factor genes. J Biol Chem. 2018 Dec 28. pii: jbc.RA118.005079. doi: 10.1074/jbc.RA118.005079. [Epub ahead of print].

Photoreceptor Progenitors Depend Upon Coordination of gdf6a, thrβ, and tbx2b to Generate Precise Populations of Cone Photoreceptor Subtypes

Authors:
DuVal MG, Allison WT
Citation:
Invest Ophthalmol Vis Sci. 2018 Dec 3;59(15):6089-6101. doi: 10.1167/iovs.18-24461
Epub:
Not Epub
Abstract:
Purpose: Replacing cone photoreceptors, the units of the retina necessary for daytime vision, depends upon the successful...
Link:
https://iovs.arvojournals.org/article.aspx?articleid=2719602
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
DuVal MG, Allison WT. Photoreceptor Progenitors Depend Upon Coordination of gdf6a, thrβ, and tbx2b to Generate Precise Populations of Cone Photoreceptor Subtypes. Invest Ophthalmol Vis Sci. 2018 Dec 3;59(15):6089-6101. doi: 10.1167/iovs.18-24461.

Fabrication of a novel DNA affinity biosensor based on hybridisation induced current by electrostatic repulsion of silicotungstic acid as a redox indicator

Authors:
Kumari P, Adeloju SB
Citation:
Talanta. 2019 Mar 1;194:127-133. doi: 10.1016/j.talanta.2018.09.074. Epub 2018 Sep 20
Epub:
Not Epub
Abstract:
We report on a novel DNA affinity biosensor which utilises the capture of a neutral charged single stranded (ss) morpholino DNA...
Link:
https://www.sciencedirect.com/science/article/pii/S0039914018309858
Citation Extract:
Kumari P, Adeloju SB. Fabrication of a novel DNA affinity biosensor based on hybridisation induced current by electrostatic repulsion of silicotungstic acid as a redox indicator. Talanta. 2019 Mar 1;194:127-133. doi: 10.1016/j.talanta.2018.09.074. Epub 2018 Sep 20.

The role of internal convection in respiratory gas transfer and aerobic metabolism in larval zebrafish ( Danio rerio)

Authors:
Hughes MC, Zimmer AM, Perry SF
Citation:
Am J Physiol Regul Integr Comp Physiol. 2019 Jan 2. doi: 10.1152/ajpregu.00315.2018. [Epub ahead of print]
Epub:
Yes
Abstract:
Purely diffusive O2 transport typically is insufficient to sustain aerobic metabolism in most multicellular organisms. In...
Link:
https://www.physiology.org/doi/abs/10.1152/ajpregu.00315.2018
Organism or Cell Type:
zebrafish
Citation Extract:
Hughes MC, Zimmer AM, Perry SF. The role of internal convection in respiratory gas transfer and aerobic metabolism in larval zebrafish ( Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2019 Jan 2. doi: 10.1152/ajpregu.00315.2018. [Epub ahead of print].

Morpholino Oligonucleotide Crosslinked Hydrogels as Portable Optical Oligonucleotide Biosensors

Authors:
Langford G, Raeburn J, Ferrier DC, Hands PJW, Shaver MP
Citation:
ACS Sens. 2018 Dec 28. doi: 10.1021/acssensors.8b01208. [Epub ahead of print]
Epub:
Yes
Abstract:
Morpholino Oligonucleotides (MOs), an uncharged DNA analogue, are functionalized with an acrylamide moiety and incorporated...
Link:
https://pubs.acs.org/doi/10.1021/acssensors.8b01208
Citation Extract:
Langford G, Raeburn J, Ferrier DC, Hands PJW, Shaver MP. Morpholino Oligonucleotide Crosslinked Hydrogels as Portable Optical Oligonucleotide Biosensors. ACS Sens. 2018 Dec 28. doi: 10.1021/acssensors.8b01208. [Epub ahead of print].

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