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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Sensing of cytosolic LPS through caspy2 pyrin domain mediates noncanonical inflammasome activation in zebrafish
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Citation:
Nat Commun. 2018 Aug 3;9(1):3052. doi: 10.1038/s41467-018-04984-1 Epub:
Not Epub Abstract:
The noncanonical inflammasome is critical for cytosolic sensing of Gram-negative pathogens. Here, we show that bacterial... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang D, Zheng X, Chen S, Wang Z, Xu W, Tan J, Hu T, Hou M, Wang W, Gu Z, Wang Q, Zhang R, Zhang Y, Liu Q. Sensing of cytosolic LPS through caspy2 pyrin domain mediates noncanonical inflammasome activation in zebrafish. Nat Commun. 2018 Aug 3;9(1):3052. doi: 10.1038/s41467-018-04984-1. |
Intracellular attenuation of BMP signaling via CKIP-1/Smurf1 is essential during neural crest induction
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Citation:
PLoS Biol. 2018 Jun 27;16(6):e2004425. doi: 10.1371/journal.pbio.2004425. eCollection 2018 Jun Epub:
Not Epub Abstract:
The neural crest is induced at the neural plate border during gastrulation by combined bone morphogenetic protein (BMP),... Delivery Method:
injection and electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Piacentino ML, Bronner ME. Intracellular attenuation of BMP signaling via CKIP-1/Smurf1 is essential during neural crest induction. PLoS Biol. 2018 Jun 27;16(6):e2004425. doi: 10.1371/journal.pbio.2004425. eCollection 2018 Jun. |
Identification of DEAD-Box RNA Helicase DDX41 as a Trafficking Protein That Involves in Multiple Innate Immune Signaling Pathways in a Zebrafish Model
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Citation:
Front Immunol. 2018 Jun 11;9:1327. doi: 10.3389/fimmu.2018.01327. eCollection 2018 Epub:
Not Epub Abstract:
DDX41 is an important sensor for host recognition of DNA viruses and initiation of nuclear factor-κB (NF-κB) and IFN signaling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ma JX, Li JY, Fan DD, Feng W, Lin AF, Xiang LX, Shao JZ. Identification of DEAD-Box RNA Helicase DDX41 as a Trafficking Protein That Involves in Multiple Innate Immune Signaling Pathways in a Zebrafish Model. Front Immunol. 2018 Jun 11;9:1327. doi: 10.3389/fimmu.2018.01327. eCollection 2018. |
Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels
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Citation:
Nat Commun. 2018 Jun 13;9(1):2302. doi: 10.1038/s41467-018-04586-x Epub:
Not Epub Abstract:
PKD2 and PKD1 genes are mutated in human autosomal dominant polycystic kidney disease. PKD2 can form either a homomeric cation... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zheng W, Yang X, Hu R, Cai R, Hofmann L, Wang Z, Hu Q, Liu X, Bulkey D, Yu Y, Tang J, Flockerzi V, Cao Y, Cao E, Chen XZ. Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels. Nat Commun. 2018 Jun 13;9(1):2302. doi: 10.1038/s41467-018-04586-x. |
Knockdown of Crispld2 in zebrafish identifies a novel network for nonsyndromic cleft lip with or without cleft palate candidate genes
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Citation:
Eur J Hum Genet. 2018 Jun 13. doi: 10.1038/s41431-018-0192-5. [Epub ahead of print] Epub:
Yes Abstract:
Orofacial development is a multifaceted process involving tightly regulated genetic signaling networks, that when perturbed,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chiquet BT, Yuan Q, Swindell EC, Maili L, Plant R, Dyke J, Boyer R, Teichgraeber JF, Greives MR, Mulliken JB, Letra A, Blanton SH, Hecht JT. Knockdown of Crispld2 in zebrafish identifies a novel network for nonsyndromic cleft lip with or without cleft palate candidate genes. Eur J Hum Genet. 2018 Jun 13. doi: 10.1038/s41431-018-0192-5. [Epub ahead of print]. |
Interaction of matrix metalloprotease-9 and Zpx in Cronobacter turicensis LMG 23827T mediated infections in the zebrafish model
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Citation:
Cell Microbiol. 2018 Jul 4:e12888. doi: 10.1111/cmi.12888. [Epub ahead of print] Epub:
Yes Abstract:
Bacteria belonging to the genus Cronobacter (C.) have been recognized as causative agents of life-threatening systemic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Eshwar AK, Wolfrum N, Stephan R, Fanning S, Lehner A. Interaction of matrix metalloprotease-9 and Zpx in Cronobacter turicensis LMG 23827T mediated infections in the zebrafish model. Cell Microbiol. 2018 Jul 4:e12888. doi: 10.1111/cmi.12888. [Epub ahead of print]. |
Morphometric analysis and neuroanatomical mapping of the zebrafish brain
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Citation:
Methods. 2018 Jun 21. pii: S1046-2023(18)30011-2. doi: 10.1016/j.ymeth.2018.06.008. [Epub ahead of print] Epub:
Yes Abstract:
Large-scale genomic studies have recently identified genetic variants causative for major neurodevelopmental disorders, such as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gupta T, Marquart GD, Horstick EJ, Tabor KM, Pajevic S, Burgess HA. Morphometric analysis and neuroanatomical mapping of the zebrafish brain. Methods. 2018 Jun 21. pii: S1046-2023(18)30011-2. doi: 10.1016/j.ymeth.2018.06.008. [Epub ahead of print]. |
A Morpholino Oligomer Therapy Regime That Restores Mitochondrial Function and Prevents mdx Cardiomyopathy
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Citation:
JACC Basic Transl Sci. 2018 Jun 25;3(3):391-402. doi: 10.1016/j.jacbts.2018.03.007. eCollection 2018 Jun Epub:
Not Epub Abstract:
Current clinical trials demonstrate Duchenne muscular dystrophy (DMD) patients receiving phosphorodiamidate morpholino oligomer... Delivery Method:
subcutaneous (s.c.) injection Organism or Cell Type:
mice mdx Citation Extract: Viola HM, Johnstone VPA, Adams AM, Fletcher S, Hool LC. A Morpholino Oligomer Therapy Regime That Restores Mitochondrial Function and Prevents mdx Cardiomyopathy. JACC Basic Transl Sci. 2018 Jun 25;3(3):391-402. doi: 10.1016/j.jacbts.2018.03.007. eCollection 2018 Jun. |
The genetic program of oocytes can be modified in vivo in the zebrafish ovary
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Citation:
J Mol Cell Biol. 2018 Jul 28. doi: 10.1093/jmcb/mjy044. [Epub ahead of print] Epub:
Yes Abstract:
Oocytes, the irreplaceable gametes for generating a new organism, are matured in the ovary of living female animals. It is... Delivery Method:
in ovo oocyte microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu X, Shen W, Zhang B, Meng A. The genetic program of oocytes can be modified in vivo in the zebrafish ovary. J Mol Cell Biol. 2018 Jul 28. doi: 10.1093/jmcb/mjy044. [Epub ahead of print]. |
Functional analysis of KCNH2 gene mutations of type 2 long QT syndrome in larval zebrafish using microscopy and electrocardiography
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Citation:
Heart Vessels. 2018 Jul 25. doi: 10.1007/s00380-018-1231-4. [Epub ahead of print] Epub:
Yes Abstract:
Heterologous expression systems play a vital role in the characterization of potassium voltage-gated channel subfamily H member... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tanaka Y, Hayashi K, Fujino N, Konno T, Tada H, Nakanishi C, Hodatsu A, Tsuda T, Nagata Y, Teramoto R, Yoshida S, Nomura A, Kawashiri MA, Yamagishi M. Functional analysis of KCNH2 gene mutations of type 2 long QT syndrome in larval zebrafish using microscopy and electrocardiography. Heart Vessels. 2018 Jul 25. doi: 10.1007/s00380-018-1231-4. [Epub ahead of print]. |