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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus

Authors:
Ma P, Ren B, Yang X, Sun B, Liu X, Kong Q, Li C, Mao B
Citation:
Open Biol. 2017 Aug;7(8). pii: 170122. doi: 10.1098/rsob.170122. Epub 2017 Aug 16
Epub:
Not Epub
Abstract:
Bone morphogenetic proteins (BMPs) play vital roles in regulating stem cell maintenance, differentiation and embryonic...
Link:
http://rsob.royalsocietypublishing.org/content/7/8/170122
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ma P, Ren B, Yang X, Sun B, Liu X, Kong Q, Li C, Mao B. ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus. Open Biol. 2017 Aug;7(8). pii: 170122. doi: 10.1098/rsob.170122. Epub 2017 Aug 16.

Homozygous Mutations in TBC1D23 Lead to a Non-degenerative Form of Pontocerebellar Hypoplasia

Authors:
Marin-Valencia I, Gerondopoulos A, Zaki MS, Ben-Omran T, Almureikhi M, Demir E, Guemez-Gamboa A, Gregor A,Issa MY, Appelhof B, Roosing S, Musaev D, Rosti B, Wirth S, Stanley V, Baas F, Barr FA, Gleeson JG
Citation:
Am J Hum Genet. 2017. {Epub ahead of print] doi:10.1016/j.ajhg.2017.07.015
Epub:
Yes
Abstract:
Pontocerebellar hypoplasia (PCH) represents a group of recessive developmental disorders characterized by impaired growth of...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297(17)30293-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marin-Valencia I, Gerondopoulos A, Zaki MS, Ben-Omran T, Almureikhi M, Demir E, Guemez-Gamboa A, Gregor A,Issa MY, Appelhof B, Roosing S, Musaev D, Rosti B, Wirth S, Stanley V, Baas F, Barr FA, Gleeson JG. Homozygous Mutations in TBC1D23 Lead to a Non-degenerative Form of Pontocerebellar Hypoplasia. Am J Hum Genet. 2017. {Epub ahead of print] doi:10.1016/j.ajhg.2017.07.015.

DAN (NBL1) promotes collective neural crest migration by restraining uncontrolled invasion

Authors:
McLennan R, Bailey CM, Schumacher LJ, Teddy JM, Morrison JA, Kasemeier-Kulesa JC, Wolfe LA, Gogol MM, Baker RE, Maini PK, Kulesa PM
Citation:
J Cell Biol. 2017 Aug 15. pii: jcb.201612169. doi: 10.1083/jcb.201612169. [Epub ahead of print]
Epub:
Yes
Abstract:
Neural crest cells are both highly migratory and significant to vertebrate organogenesis. However, the signals that regulate...
Link:
http://jcb.rupress.org/content/early/2017/08/14/jcb.201612169
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
McLennan R, Bailey CM, Schumacher LJ, Teddy JM, Morrison JA, Kasemeier-Kulesa JC, Wolfe LA, Gogol MM, Baker RE, Maini PK, Kulesa PM. DAN (NBL1) promotes collective neural crest migration by restraining uncontrolled invasion. J Cell Biol. 2017 Aug 15. pii: jcb.201612169. doi: 10.1083/jcb.201612169. [Epub ahead of print].

The loss and recovery of vertebrate vision examined in microplates

Authors:
Thorn RJ, Clift DE, Ojo O, Colwill RM, Creton R
Citation:
PLoS ONE. 2017;12(8):e0183414. doi:10.1371/journal.pone.0183414
Epub:
Not Epub
Abstract:
Regenerative medicine offers potentially ground-breaking treatments of blindness and low vision. However, as new methodologies...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0183414
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thorn RJ, Clift DE, Ojo O, Colwill RM, Creton R. The loss and recovery of vertebrate vision examined in microplates. PLoS ONE. 2017;12(8):e0183414. doi:10.1371/journal.pone.0183414.

Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes

Authors:
Seguin A, Takahashi-Makise N, Yien YY, Huston NC, Whitman JC, Musso G, Wallace JA, Bradley T, Bergonia H, Kafina MD, Matsumoto M, Igarashi K, Phillips JD, Paw BH, Kaplan J, Ward DM
Citation:
J Biol Chem. 2017 Aug 14. pii: jbc.M117.797415. doi: 10.1074/jbc.M117.797415. [Epub ahead of print]
Epub:
Yes
Abstract:
ATP-binding cassette subfamily B member 10 (Abcb10) is a mitochondrial ABC transporter that complexes with mitoferrin1 and...
Link:
http://www.jbc.org/content/early/2017/08/14/jbc.M117.797415.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Seguin A, Takahashi-Makise N, Yien YY, Huston NC, Whitman JC, Musso G, Wallace JA, Bradley T, Bergonia H, Kafina MD, Matsumoto M, Igarashi K, Phillips JD, Paw BH, Kaplan J, Ward DM. Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes. J Biol Chem. 2017 Aug 14. pii: jbc.M117.797415. doi: 10.1074/jbc.M117.797415. [Epub ahead of print].

Targeting a single alternative polyadenylation site coordinately blocks expression of androgen receptor mRNA splice variants in prostate cancer

Authors:
Van Etten JL, Nyquist M, Li Y, Yang R, Ho Y, Johnson RM, Ondigi O, Voytas DF, Henzler C, Dehm SM
Citation:
Cancer Res. 2017 Aug 15. pii: canres.0320.2017. doi: 10.1158/0008-5472.CAN-17-0320. [Epub ahead of print]
Epub:
Yes
Abstract:
Prostate cancer is the second leading cause of male cancer deaths due to disease progression to castration resistant prostate...
Link:
http://cancerres.aacrjournals.org/content/early/2017/08/15/0008-5472.CAN-17-0320
Organism or Cell Type:
cell culture: castration resistant prostate cancer (CRPC) cells
Citation Extract:
Van Etten JL, Nyquist M, Li Y, Yang R, Ho Y, Johnson RM, Ondigi O, Voytas DF, Henzler C, Dehm SM. Targeting a single alternative polyadenylation site coordinately blocks expression of androgen receptor mRNA splice variants in prostate cancer. Cancer Res. 2017 Aug 15. pii: canres.0320.2017. doi: 10.1158/0008-5472.CAN-17-0320. [Epub ahead of print].

The RNF146 E3 ubiquitin ligase is required for the control of Wnt signaling and body pattern formation in Xenopus

Authors:
Zhu X, Xing R, Tan R, Dai R, Tao Q
Citation:
Mech Dev. 2017 Aug 11. pii: S0925-4773(17)30074-6. doi: 10.1016/j.mod.2017.08.001. [Epub ahead of print]
Epub:
Yes
Abstract:
The RING finger protein Rnf146 encodes an E3 ubiquitin ligase capable of targeting poly-ADP-ribosylated substrates for...
Link:
http://www.sciencedirect.com/science/article/pii/S0925477317300746
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Zhu X, Xing R, Tan R, Dai R, Tao Q. The RNF146 E3 ubiquitin ligase is required for the control of Wnt signaling and body pattern formation in Xenopus. Mech Dev. 2017 Aug 11. pii: S0925-4773(17)30074-6. doi: 10.1016/j.mod.2017.08.001. [Epub ahead of print].

Cell interactions, signals and transcriptional hierarchy governing placode progenitor induction

Authors:
Hintze M, Prajapati RS, Tambalo M, Christophorou NAD, Anwar M, Grocott T, Streit A
Citation:
Development. 2017 Aug 1;144(15):2810-2823. doi: 10.1242/dev.147942. Epub 2017 Jul 6
Epub:
Not Epub
Abstract:
In vertebrates, cranial placodes contribute to all sense organs and sensory ganglia and arise from a common pool of Six1/Eya2+...
Link:
http://dev.biologists.org/content/144/15/2810
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Hintze M, Prajapati RS, Tambalo M, Christophorou NAD, Anwar M, Grocott T, Streit A. Cell interactions, signals and transcriptional hierarchy governing placode progenitor induction. Development. 2017 Aug 1;144(15):2810-2823. doi: 10.1242/dev.147942. Epub 2017 Jul 6.

Wnt signalling controls the response to mechanical loading during zebrafish joint development

Authors:
Brunt LH, Begg K, Kague E, Cross S, Hammond CL
Citation:
Development. 2017 Aug 1;144(15):2798-2809. doi: 10.1242/dev.153528. Epub 2017 Jul 6
Epub:
Not Epub
Abstract:
Joint morphogenesis requires mechanical activity during development. Loss of mechanical strain causes abnormal joint...
Link:
http://dev.biologists.org/content/144/15/2798
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brunt LH, Begg K, Kague E, Cross S, Hammond CL. Wnt signalling controls the response to mechanical loading during zebrafish joint development. Development. 2017 Aug 1;144(15):2798-2809. doi: 10.1242/dev.153528. Epub 2017 Jul 6.

Ikk2 regulates cytokinesis during vertebrate development

Authors:
Shen H, Shin EM, Lee S, Mathavan S, Koh H, Osato M, Choi H, Tergaonkar V, Korzh V
Citation:
Sci Rep. 2017;7:8094. doi:10.1038/s41598-017-06904-7
Epub:
Not Epub
Abstract:
NFκB signaling has a pivotal role in regulation of development, innate immunity, and inflammation. Ikk2 is one of the two...
Link:
https://www.nature.com/articles/s41598-017-06904-7
Organism or Cell Type:
zebrafish
Citation Extract:
Shen H, Shin EM, Lee S, Mathavan S, Koh H, Osato M, Choi H, Tergaonkar V, Korzh V. Ikk2 regulates cytokinesis during vertebrate development. Sci Rep. 2017;7:8094. doi:10.1038/s41598-017-06904-7.

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