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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Transient knock-down of kcna2 reduces sleep in larval zebrafish
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Citation:
Behav Brain Res. 2017 Feb 18. pii: S0166-4328(16)30882-8. doi: 10.1016/j.bbr.2017.02.026. [Epub ahead of print] Epub:
Yes Abstract:
In the current study we set out to determine the effects of morpholino oligonucleotide (MO) knock-down of kcna2 on sleep-wake... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Srdanovic S, Þorsteinsson H, FriÐriksson Þ, Pétursson SÓ, Maier VH, Karlsson KÆ. Transient knock-down of kcna2 reduces sleep in larval zebrafish. Behav Brain Res. 2017 Feb 18. pii: S0166-4328(16)30882-8. doi: 10.1016/j.bbr.2017.02.026. [Epub ahead of print]. |
Leftward Flow Determines Laterality in Conjoined Twins
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Citation:
Curr Biol. 2017 Feb 20;27(4):543-548. doi: 10.1016/j.cub.2016.12.049 Epub:
Not Epub Abstract:
Conjoined twins fused at the thorax display an enigmatic left-right defect: although left twins are normal, laterality is... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Tisler M, Thumberger T, Schneider I, Schweickert A, Blum M. Leftward Flow Determines Laterality in Conjoined Twins. Curr Biol. 2017 Feb 20;27(4):543-548. doi: 10.1016/j.cub.2016.12.049. |
A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse
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Citation:
Sci Rep. 2017;7:43010. doi:10.1038/srep43010 Epub:
Not Epub Abstract:
Goosecoid (Gsc) expression marks the primary embryonic organizer in vertebrates and beyond. While functions have been assigned... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Ulmer B, Tingler M, Kurz S, Maerker M, Andre P, Mönch D, Campione M, Deißler K, Lewandoski M, Thumberger T, Schweickert A, Fainsod A, Steinbeißer H, Blum M. A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse. Sci Rep. 2017;7:43010. doi:10.1038/srep43010. |
Vegfa Impacts Early Myocardium Development in Zebrafish
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Citation:
Int J Mol Sci. 2017;18(2):444 doi:10.3390/ijms18020444 Epub:
Not Epub Abstract:
Vascular endothelial growth factor A (Vegfa) signaling regulates cardiovascular development. However, the cellular mechanisms... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhu D, Fang Y, Gao K, Shen J, Zhong TP, Li F. Vegfa Impacts Early Myocardium Development in Zebrafish. Int J Mol Sci. 2017;18(2):444 doi:10.3390/ijms18020444. |
Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation
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Citation:
PLoS Genet. 2017;13(2):e1006564. doi:10.1371/journal.pgen.1006564 Epub:
Not Epub Abstract:
Cell proliferation has generally been considered dispensable for anteroposterior extension of embryonic axis during vertebrate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu Y, Sepich DS, Solnica-Krezel L. Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation. PLoS Genet. 2017;13(2):e1006564. doi:10.1371/journal.pgen.1006564. |
A girl with developmental delay, ataxia, cranial nerve palsies, severe respiratory problems in infancy-Expanding NDST1 syndrome
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Citation:
Am J Med Genet A. 2017 Mar;173(3):712-715. doi: 10.1002/ajmg.a.37621 Epub:
Not Epub Abstract:
NDST1 encodes an enzyme involved in the first steps in the synthesis of heparan sulfate chains, proteoglycans that are... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Armstrong L, Tarailo-Graovac M, Sinclair G, Seath KI, Wasserman WW, Ross CJ, van Karnebeek CD. A girl with developmental delay, ataxia, cranial nerve palsies, severe respiratory problems in infancy-Expanding NDST1 syndrome. Am J Med Genet A. 2017 Mar;173(3):712-715. doi: 10.1002/ajmg.a.37621. |
The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions
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Citation:
J Vis Exp. 2017;120:e55113. doi:10.3791/55113 Epub:
Not Epub Abstract:
Remarkably few cell-to-cell signal transduction pathways are necessary during embryonic development to generate the large... Organism or Cell Type:
sea urchin Citation Extract: Range RC, Martinez-Bartolomé M, Burr SD. The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions. J Vis Exp. 2017;120:e55113. doi:10.3791/55113. |
Hyaluronic acid synthesis is required for zebrafish tail fin regeneration
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Citation:
PLoS One. 2017 Feb 16;12(2):e0171898. doi: 10.1371/journal.pone.0171898 Epub:
Not Epub Abstract:
Using genome-wide transcriptional profiling and whole-mount expression analyses of zebrafish larvae, we have identified... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ouyang X, Panetta NJ, Talbott MD, Payumo AY, Halluin C, Longaker MT, Chen JK. Hyaluronic acid synthesis is required for zebrafish tail fin regeneration. PLoS One. 2017 Feb 16;12(2):e0171898. doi: 10.1371/journal.pone.0171898. |
The enteric nervous system promotes intestinal health by constraining microbiota composition
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Citation:
PLoS Biol. 2017 Feb 16;15(2):e2000689. doi: 10.1371/journal.pbio.2000689 Epub:
Not Epub Abstract:
Sustaining a balanced intestinal microbial community is critical for maintaining intestinal health and preventing chronic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rolig AS, Mittge EK, Ganz J, Troll JV, Melancon E, Wiles TJ, Alligood K, Stephens WZ, Eisen JS, Guillemin K. The enteric nervous system promotes intestinal health by constraining microbiota composition. PLoS Biol. 2017 Feb 16;15(2):e2000689. doi: 10.1371/journal.pbio.2000689. |
Morpholino-based correction of hypomorphic ZAP70 mutation in an adult with combined immunodeficiency
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Citation:
J Allergy Clin Immunol. 2017 May;139(5):1688-1692.e10. doi: 10.1016/j.jaci.2017.02.002. Epub 2017 Feb 17. PMID: 28216435; PMCID: PMC7126384 Epub:
Yes Abstract:
An adult with hypomorphic ZAP-70 deficiency due to de novo donor splice site mutation manifested autoimmunity, infections... Citation Extract: Gavino C, Landekic M, Zeng J, Wu N, Jung S, Zhong MC, Cohen-Blanchet A, Langelier M, Neyret O, Lejtenyi D, Rochefort C, Cotton-Montpetit J, McCusker C, Mazer B, Veillette A, Vinh DC. Morpholino-based correction of hypomorphic ZAP70 mutation in an adult with combined immunodeficiency. J Allergy Clin Immunol. 2017 May;139(5):1688-1692.e10. doi: 10.1016/j.jaci.2017.02.002. Epub 2017 Feb 17. PMID: 28216435; PMCID: PMC7126384. |