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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Glycerophosphodiesterase GDE2 affects pancreas differentiation in zebrafish

Authors:
Veen M, van Pelt J, Mans LA, Moolenaar WH, Haramis A-PG
Citation:
bioRxiv. 2017. doi:10.1101/108779
Epub:
Yes
Abstract:
Notch signaling plays an essential role in the proliferation, differentiation and cell fate determination of various tissues,...
Link:
biorxiv.org/content/biorxiv/early/2017/02/15/108779.full.pdf
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Veen M, van Pelt J, Mans LA, Moolenaar WH, Haramis A-PG. Glycerophosphodiesterase GDE2 affects pancreas differentiation in zebrafish. bioRxiv. 2017. doi:10.1101/108779.

Mechanical stretch triggers rapid epithelial cell division through Piezo1

Authors:
Gudipaty SA, Lindblom J, Loftus PD, Redd MJ, Edes K, Davey CF, Krishnegowda V, Rosenblatt J
Citation:
Nature. 2017;543:118–121. doi:10.1038/nature21407
Epub:
Yes
Abstract:
Despite acting as a barrier for the organs they encase, epithelial cells turn over at some of the fastest rates in the body....
Link:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature21407.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gudipaty SA, Lindblom J, Loftus PD, Redd MJ, Edes K, Davey CF, Krishnegowda V, Rosenblatt J. Mechanical stretch triggers rapid epithelial cell division through Piezo1. Nature. 2017;543:118–121. doi:10.1038/nature21407.

The host microRNA miR-301a blocks the IRF1-mediated neuronal innate immune response to Japanese encephalitis virus infection

Authors:
Hazra B, Kumawat KL, Basu A
Citation:
Sci Signal. 2017;10(466):eaaf5185. doi:10.1126/scisignal.aaf5185
Epub:
Not Epub
Abstract:
Effective recognition of viral components and the subsequent stimulation of the production of type I interferons (IFNs) is...
Link:
http://stke.sciencemag.org/content/10/466/eaaf5185
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
BALB/c mice
Citation Extract:
Hazra B, Kumawat KL, Basu A. The host microRNA miR-301a blocks the IRF1-mediated neuronal innate immune response to Japanese encephalitis virus infection. Sci Signal. 2017;10(466):eaaf5185. doi:10.1126/scisignal.aaf5185.

Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction

Authors:
Elmonem MA, Khalil R, Khodaparast L, Khodaparast L, Arcolino FO, Morgan J, Pastore A, Tylzanowski P, Ny A, Lowe M, de Witte PA, Baelde HJ, van den Heuvel LP, Levtchenko E
Citation:
Sci Rep. 2017;7:42583. doi:10.1038/srep42583
Epub:
Not Epub
Abstract:
The human ubiquitous protein cystinosin is responsible for transporting the disulphide amino acid cystine from the lysosomal...
Link:
http://www.nature.com/articles/srep42583
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Elmonem MA, Khalil R, Khodaparast L, Khodaparast L, Arcolino FO, Morgan J, Pastore A, Tylzanowski P, Ny A, Lowe M, de Witte PA, Baelde HJ, van den Heuvel LP, Levtchenko E. Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction. Sci Rep. 2017;7:42583. doi:10.1038/srep42583.

Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling

Authors:
Han W, Lee H, Han J-K
Citation:
Sci Rep. 2017;7:42590 doi:10.1038/srep42590
Epub:
Not Epub
Abstract:
The Tcf/Lef family of transcription factors mediates the Wnt/β-catenin pathway that is involved in a wide range of biological...
Link:
http://www.nature.com/articles/srep42590
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Han W, Lee H, Han J-K. Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling. Sci Rep. 2017;7:42590 doi:10.1038/srep42590.

Dual roles of Akirin2 during Xenopus neural development

Authors:
Liu X, Xia Y, Tang J, Ma L, Li C, Ma P, Mao B
Citation:
J Biol Chem. 2017 Feb 13. pii: jbc.M117.777110. doi: 10.1074/jbc.M117.777110. [Epub ahead of print]
Epub:
Yes
Abstract:
To ensure correct spatial and temporal patterning, embryos must maintain pluripotent cell populations and control when cells...
Link:
http://www.jbc.org/content/early/2017/02/13/jbc.M117.777110.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Liu X, Xia Y, Tang J, Ma L, Li C, Ma P, Mao B. Dual roles of Akirin2 during Xenopus neural development. J Biol Chem. 2017 Feb 13. pii: jbc.M117.777110. doi: 10.1074/jbc.M117.777110. [Epub ahead of print].

Snail2 and Zeb2 repress P-Cadherin to define embryonic territories in the chick embryo

Authors:
Acloque H, Ocaña OH, Abad D, Stern CD, Nieto MA
Citation:
Development. 2017 Jan 13. pii: dev.142562. doi: 10.1242/dev.142562. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Snail and Zeb transcription factors induce epithelial to mesenchymal transition (EMT) in embryonic and adult tissues by direct...
Link:
http://dev.biologists.org/content/144/4/649.long
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Acloque H, Ocaña OH, Abad D, Stern CD, Nieto MA. Snail2 and Zeb2 repress P-Cadherin to define embryonic territories in the chick embryo. Development. 2017 Jan 13. pii: dev.142562. doi: 10.1242/dev.142562. [Epub ahead of print].

Analysis of Craniocardiac Malformations in Xenopus using Optical Coherence Tomography

Authors:
Deniz E, Jonas S, Hooper M, Griffin JN, Choma MA, Khokha MF
Citation:
Sci Rep. 2017;7:42506. doi:10.1038/srep42506
Epub:
Not Epub
Abstract:
Birth defects affect 3% of children in the United States. Among the birth defects, congenital heart disease and craniofacial...
Link:
http://www.nature.com/articles/srep42506
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Deniz E, Jonas S, Hooper M, Griffin JN, Choma MA, Khokha MF. Analysis of Craniocardiac Malformations in Xenopus using Optical Coherence Tomography. Sci Rep. 2017;7:42506. doi:10.1038/srep42506.

m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition

Authors:
Zhao BS, Wang X, Beadell AV, Lu Z, Shi H, Kuuspalu A, Ho RK, He C
Citation:
Nature. 2017 Feb 13. doi: 10.1038/nature21355. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The maternal-to-zygotic transition (MZT) is one of the most profound and tightly orchestrated processes during the early life...
Link:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature21355.html
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao BS, Wang X, Beadell AV, Lu Z, Shi H, Kuuspalu A, Ho RK, He C. m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition. Nature. 2017 Feb 13. doi: 10.1038/nature21355. [Epub ahead of print].

Cyp1b1 Regulates Ocular Fissure Closure Through a Retinoic Acid-Independent Pathway

Authors:
Williams AL, Eason J, Chawla B, Bohnsack BL
Citation:
Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1084-1097. doi: 10.1167/iovs.16-20235
Epub:
Not Epub
Abstract:
Purpose: Mutations in the CYP1B1 gene are the most commonly identified genetic causes of primary infantile-onset glaucoma....
Link:
http://iovs.arvojournals.org/article.aspx?articleid=2603905
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Williams AL, Eason J, Chawla B, Bohnsack BL. Cyp1b1 Regulates Ocular Fissure Closure Through a Retinoic Acid-Independent Pathway. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1084-1097. doi: 10.1167/iovs.16-20235.

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