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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Comparison of Zebrafish tmem88a mutant and morpholino knockdown phenotypes

Authors:
Eve AM, Place ES, Smith JC
Citation:
PLoS One. 2017 Feb 13;12(2):e0172227. doi: 10.1371/journal.pone.0172227
Epub:
Not Epub
Abstract:
Tmem88a is a transmembrane protein that is thought to be a negative regulator of the Wnt signalling pathway. Several groups...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172227
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Eve AM, Place ES, Smith JC. Comparison of Zebrafish tmem88a mutant and morpholino knockdown phenotypes. PLoS One. 2017 Feb 13;12(2):e0172227. doi: 10.1371/journal.pone.0172227.

The Neuropeptide Galanin Is Up-Regulated during Cholestasis and Contributes to Cholangiocyte Proliferation

Authors:
McMillin M, Frampton G, Grant S, DeMorrow S
Citation:
Am J Pathol. 2017;[Epub ahead of print] doi:10.1016/j.ajpath.2016.12.015
Epub:
Yes
Abstract:
During the course of cholestatic liver diseases, mitotically dormant cholangiocytes proliferate and subsequently acquire a...
Link:
http://ajp.amjpathol.org/article/S0002-9440(17)30065-2/abstract
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
rat
Citation Extract:
McMillin M, Frampton G, Grant S, DeMorrow S. The Neuropeptide Galanin Is Up-Regulated during Cholestasis and Contributes to Cholangiocyte Proliferation. Am J Pathol. 2017;[Epub ahead of print] doi:10.1016/j.ajpath.2016.12.015.

The small GTPase Arf6 regulates sea urchin morphogenesis

Authors:
Stepicheva NA, Dumas M, Kobi P, Donaldson JG, Song JL
Citation:
Differentiation. 2017 Feb 2;95:31-43. doi: 10.1016/j.diff.2017.01.003. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The small GTPase Arf6 is a conserved protein that is expressed in all metazoans. Arf6 remodels cytoskeletal actin and mediates...
Link:
http://www.sciencedirect.com/science/article/pii/S030146811630069X
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Stepicheva NA, Dumas M, Kobi P, Donaldson JG, Song JL. The small GTPase Arf6 regulates sea urchin morphogenesis. Differentiation. 2017 Feb 2;95:31-43. doi: 10.1016/j.diff.2017.01.003. [Epub ahead of print].

Mutations in INPP5K, Encoding a Phosphoinositide 5-Phosphatase, Cause Congenital Muscular Dystrophy with Cataracts and Mild Cognitive Impairment

Authors:
Wiessner M, Roos A, Munn CJ, Viswanathan R, Whyte T, Cox D, Schoser B, Sewry C, Roper H, Phadke R, Marini Bettolo CM, Barresi R, Charlton R, Bönnemann CG, Neto OA, Reed UC, Zanoteli E, Moreno CAM, Ertl-Wagner B, Stucka R, De Goede C, da Silva TB, Hathazi D, Dell’Aica M, Zahedi RP, Thiele S, Müller J, Kingston H, Müller S, Curtis E, Walter MC, Strom TM, Straub V, Bushby K, Muntoni F, Swan LE, Lochmüller H, Senderek J
Citation:
Am J Hum Genet. 2017;[Epub ahead of print] doi:10.1016/j.ajhg.2017.01.024
Epub:
Yes
Abstract:
Phosphoinositides are small phospholipids that control diverse cellular downstream signaling events. Their spatial and temporal...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297(17)30024-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wiessner M, Roos A, Munn CJ, Viswanathan R, Whyte T, Cox D, Schoser B, Sewry C, Roper H, Phadke R, Marini Bettolo CM, Barresi R, Charlton R, Bönnemann CG, Neto OA, Reed UC, Zanoteli E, Moreno CAM, Ertl-Wagner B, Stucka R, De Goede C, da Silva TB, Hathazi D, Dell’Aica M, Zahedi RP, Thiele S, Müller J, Kingston H, Müller S, Curtis E, Walter MC, Strom TM, Straub V, Bushby K, Muntoni F, Swan LE, Lochmüller H, Senderek J. Mutations in INPP5K, Encoding a Phosphoinositide 5-Phosphatase, Cause Congenital Muscular Dystrophy with Cataracts and Mild Cognitive Impairment. Am J Hum Genet. 2017;[Epub ahead of print] doi:10.1016/j.ajhg.2017.01.024.

Impairment of cargo transportation due to gbf1 mutation disrupts vascular integrity and causes hemorrhage in zebrafish embryos

Authors:
Chen J, Wu X, Yao L, Yan L, Zhang L, Qiu J, Liu X, Jia S, Meng A
Citation:
J Biol Chem. 2016 Dec 21. pii: jbc.M116.767608. doi: 10.1074/jbc.M116.767608. [Epub ahead of print]
Epub:
Yes
Abstract:
ADP-ribosylation factor (ARF) GTPases are activated by guanine nucleotide exchange factors including Golgi Brefeldin A-...
Link:
http://www.jbc.org/content/292/6/2315.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Chen J, Wu X, Yao L, Yan L, Zhang L, Qiu J, Liu X, Jia S, Meng A. Impairment of cargo transportation due to gbf1 mutation disrupts vascular integrity and causes hemorrhage in zebrafish embryos. J Biol Chem. 2016 Dec 21. pii: jbc.M116.767608. doi: 10.1074/jbc.M116.767608. [Epub ahead of print].

Mutations in INPP5K Cause a Form of Congenital Muscular Dystrophy Overlapping Marinesco-Sjögren Syndrome and Dystroglycanopathy

Authors:
Osborn DPS, Pond HL, Mazaheri N, Dejardin J, Munn CJ, Mushref K, Cauley ES, Moroni I, Pasanisi MB, Sellars EA, Hill RS, Partlow JN, Willaert RK, Bharj J, Malamiri RA, Galehdari H, Shariati G, Maroofian R, Mora M, Swan LE, Voit T, Conti FJ, Jamshidi Y, Manzini MC
Citation:
Am J Hum Genet. 2017;[Epub ahead of print] doi:10.1016/j.ajhg.2017.01.019
Epub:
Not Epub
Abstract:
Congenital muscular dystrophies display a wide phenotypic and genetic heterogeneity. The combination of clinical, biochemical,...
Link:
http://www.cell.com/ajhg/fulltext/S0002-9297(17)30019-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Osborn DPS, Pond HL, Mazaheri N, Dejardin J, Munn CJ, Mushref K, Cauley ES, Moroni I, Pasanisi MB, Sellars EA, Hill RS, Partlow JN, Willaert RK, Bharj J, Malamiri RA, Galehdari H, Shariati G, Maroofian R, Mora M, Swan LE, Voit T, Conti FJ, Jamshidi Y, Manzini MC. Mutations in INPP5K Cause a Form of Congenital Muscular Dystrophy Overlapping Marinesco-Sjögren Syndrome and Dystroglycanopathy. Am J Hum Genet. 2017;[Epub ahead of print] doi:10.1016/j.ajhg.2017.01.019.

Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes

Authors:
Place ES, Smith JC
Citation:
PLoS One. 2017 Feb 9;12(2):e0171143. doi: 10.1371/journal.pone.0171143
Epub:
Not Epub
Abstract:
Atoh8 is a bHLH transcription factor expressed in pancreas, skeletal muscle, the nervous system, and cardiovascular tissues...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0171143
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Place ES, Smith JC. Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes. PLoS One. 2017 Feb 9;12(2):e0171143. doi: 10.1371/journal.pone.0171143.

Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling

Authors:
Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K
Citation:
Circul Res. 2017;[Epub ahead of print] doi:10.1161/CIRCRESAHA.116.308825
Epub:
Not Epub
Abstract:
Rationale: Lymphatic vasculature constitutes a second vascular system, essential for immune surveillance and tissue fluid...
Link:
http://circres.ahajournals.org/content/early/2017/02/08/CIRCRESAHA.116.308825
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K. Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling. Circul Res. 2017;[Epub ahead of print] doi:10.1161/CIRCRESAHA.116.308825.

Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors

Authors:
Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee H-Y, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, Agarwal S, Ebert BL, Gazda HT, Lodish HF, Sieff CA, Schlaeger TM, Zon LI, Daley GQ
Citation:
Science Transl Med. 2017;9(376). doi:10.1126/scitranslmed.aah5645
Epub:
Not Epub
Abstract:
Diamond-Blackfan anemia (DBA) is a congenital disorder characterized by the failure of erythroid progenitor differentiation,...
Link:
http://stm.sciencemag.org/content/9/376/eaah5645.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee H-Y, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, Agarwal S, Ebert BL, Gazda HT, Lodish HF, Sieff CA, Schlaeger TM, Zon LI, Daley GQ. Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors. Science Transl Med. 2017;9(376). doi:10.1126/scitranslmed.aah5645.

DM-GRASP/ALCAM/CD166 is required for cardiac morphogenesis and maintenance of cardiac identity in first heart field derived cells

Authors:
Gessert S, Maurus D, Brade T, Walther P, Pandur P, Kühl M
Citation:
Dev Biol. 2008 Sep 1;321(1):150-61. doi: 10.1016/j.ydbio.2008.06.013
Epub:
Not Epub
Abstract:
Vertebrate heart development requires specification of cardiac precursor cells, migration of cardiac progenitors as well as...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160608010038
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gessert S, Maurus D, Brade T, Walther P, Pandur P, Kühl M. DM-GRASP/ALCAM/CD166 is required for cardiac morphogenesis and maintenance of cardiac identity in first heart field derived cells. Dev Biol. 2008 Sep 1;321(1):150-61. doi: 10.1016/j.ydbio.2008.06.013.

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