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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

NgAgo-based fabp11a gene knockdown causes eye developmental defects in zebrafish

Authors:
Qi J, Dong Z, Shi Y, Wang X, Qin Y, Wang Y, Liu D
Citation:
Cell Res. 2016 Nov 11. doi: 10.1038/cr.2016.134. [Epub ahead of print] No abstract available
Epub:
Not Epub
Abstract:
A recent report of genome editing using Natronobacterium gregoryi Argonaute (NgAgo) with guide DNA (gDNA) in human cells...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Qi J, Dong Z, Shi Y, Wang X, Qin Y, Wang Y, Liu D. NgAgo-based fabp11a gene knockdown causes eye developmental defects in zebrafish. Cell Res. 2016 Nov 11. doi: 10.1038/cr.2016.134. [Epub ahead of print] No abstract available.

Identification of medaka magnetoreceptor and cryptochromes

Authors:
Wang Y, Chen J, Zhu F, Hong Y
Citation:
Sci China Life Sci. 2016 Nov 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Magnetoreception is a hallmark ability of animals for orientation and migration via sensing and utilizing geomagnetic fields....
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Wang Y, Chen J, Zhu F, Hong Y. Identification of medaka magnetoreceptor and cryptochromes. Sci China Life Sci. 2016 Nov 17. [Epub ahead of print].

Somite-Derived Retinoic Acid Regulates Zebrafish Hematopoietic Stem Cell Formation

Authors:
Pillay LM, Mackowetzky KJ, Widen SA, Waskiewicz AJ
Citation:
PLoS One. 2016 Nov 18;11(11):e0166040. doi: 10.1371/journal.pone.0166040
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) are multipotent progenitors that generate all vertebrate adult blood lineages. Recent analyses...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pillay LM, Mackowetzky KJ, Widen SA, Waskiewicz AJ. Somite-Derived Retinoic Acid Regulates Zebrafish Hematopoietic Stem Cell Formation. PLoS One. 2016 Nov 18;11(11):e0166040. doi: 10.1371/journal.pone.0166040.

Alternative Splicing of Four Trafficking Genes Regulates Myofiber Structure and Skeletal Muscle Physiology

Authors:
Giudice J, Loehr JA, Rodney GG, Cooper TA
Citation:
Cell Rep. 2016 Nov 15;17(8):1923-1933. doi: 10.1016/j.celrep.2016.10.072
Epub:
Not Epub
Abstract:
During development, transcriptional and post-transcriptional networks are coordinately regulated to drive organ maturation....
Delivery Method:
injection then electroporation
Organism or Cell Type:
mouse
Citation Extract:
Giudice J, Loehr JA, Rodney GG, Cooper TA. Alternative Splicing of Four Trafficking Genes Regulates Myofiber Structure and Skeletal Muscle Physiology. Cell Rep. 2016 Nov 15;17(8):1923-1933. doi: 10.1016/j.celrep.2016.10.072.

Glucosylceramide transferase in Giardia preferentially catalyzes the synthesis of galactosylceramide during encystation

Authors:
Robles-Martinez L, Mendez TL, Apodaca J, Das S
Citation:
Mol Biochem Parasitol. 2016 Nov 10. pii: S0166-6851(16)30132-3. doi: 10.1016/j.molbiopara.2016.11.001. [Epub ahead of print]
Epub:
Yes
Abstract:
The stage differentiation from trophozoite to cyst (i.e., encystation) is an essential step for Giardia to survive outside its...
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Robles-Martinez L, Mendez TL, Apodaca J, Das S. Glucosylceramide transferase in Giardia preferentially catalyzes the synthesis of galactosylceramide during encystation. Mol Biochem Parasitol. 2016 Nov 10. pii: S0166-6851(16)30132-3. doi: 10.1016/j.molbiopara.2016.11.001. [Epub ahead of print].

Genetic and pharmacological inhibition of CDK9 drives neutrophil apoptosis to resolve inflammation in zebrafish in vivo

Authors:
Hoodless LJ, Lucas CD, Duffin R, Denvir MA, Haslett C, Tucker CS, Rossi AG
Citation:
Sci Rep. 2016 Nov 11;5:36980. doi: 10.1038/srep36980
Epub:
Not Epub
Abstract:
Neutrophilic inflammation is tightly regulated and subsequently resolves to limit tissue damage and promote repair. When the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hoodless LJ, Lucas CD, Duffin R, Denvir MA, Haslett C, Tucker CS, Rossi AG. Genetic and pharmacological inhibition of CDK9 drives neutrophil apoptosis to resolve inflammation in zebrafish in vivo. Sci Rep. 2016 Nov 11;5:36980. doi: 10.1038/srep36980.

miRNA-487a Promotes Proliferation and Metastasis in Hepatocellular Carcinoma

Authors:
Chang RM, Xiao S, Lei X, Yang H, Fang F, Yang LY
Citation:
Clin Cancer Res. 2017 May 15;23(10):2593-2604. doi: 10.1158/1078-0432.CCR-16-0851. Epub 2016 Nov 8. PMID: 27827315
Epub:
Yes
Abstract:
Purpose: Hepatocellular carcinoma (HCC) harbors highly metastatic properties, accounting for postoperative recurrence and...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse
Citation Extract:
Chang RM, Xiao S, Lei X, Yang H, Fang F, Yang LY. miRNA-487a Promotes Proliferation and Metastasis in Hepatocellular Carcinoma. Clin Cancer Res. 2017 May 15;23(10):2593-2604. doi: 10.1158/1078-0432.CCR-16-0851. Epub 2016 Nov 8. PMID: 27827315.

Copy number variation as a genetic basis for heterotaxy and heterotaxy-spectrum congenital heart defects

Authors:
Cowan JR, Tariq M, Shaw C, Rao M, Belmont JW, Lalani SR, Smolarek TA, Ware SM
Citation:
Philos Trans R Soc Lond B Biol Sci. 2016 Dec 19;371(1710). pii: 20150406
Epub:
Not Epub
Abstract:
Genomic disorders and rare copy number abnormalities are identified in 15-25% of patients with syndromic conditions, but their...
Organism or Cell Type:
Xenopus
Citation Extract:
Cowan JR, Tariq M, Shaw C, Rao M, Belmont JW, Lalani SR, Smolarek TA, Ware SM. Copy number variation as a genetic basis for heterotaxy and heterotaxy-spectrum congenital heart defects. Philos Trans R Soc Lond B Biol Sci. 2016 Dec 19;371(1710). pii: 20150406.

Retinoic acid catabolizing enzyme CYP26C1 is a genetic modifier in SHOX deficiency

Authors:
Montalbano A, Juergensen L, Roeth R, Weiss B, Fukami M, Fricke‐Otto S, Binder G, Ogata T, Decker E, Nuernberg G, Hassel D, Rappold GA
Citation:
EMBO Molec Med. 2016;[Epub] doi:10.15252/emmm.201606623
Epub:
Yes
Abstract:
Mutations in the homeobox gene SHOX cause SHOX deficiency, a condition with clinical manifestations ranging from short stature...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Montalbano A, Juergensen L, Roeth R, Weiss B, Fukami M, Fricke‐Otto S, Binder G, Ogata T, Decker E, Nuernberg G, Hassel D, Rappold GA. Retinoic acid catabolizing enzyme CYP26C1 is a genetic modifier in SHOX deficiency. EMBO Molec Med. 2016;[Epub] doi:10.15252/emmm.201606623.

EphrinB1/EphB3b Coordinate Bidirectional Epithelial-Mesenchymal Interactions Controlling Liver Morphogenesis and Laterality

Authors:
Cayuso J, Dzementsei A, Fischer JC, Karemore G, Caviglia S, Bartholdson J, Wright GJ, Ober EA
Citation:
Dev Cell. 2016;39(3):316-28. doi:10.1016/j.devcel.2016.10.009
Epub:
Not Epub
Abstract:
Positioning organs in the body often requires the movement of multiple tissues, yet the molecular and cellular mechanisms...
Organism or Cell Type:
zebrafish
Citation Extract:
Cayuso J, Dzementsei A, Fischer JC, Karemore G, Caviglia S, Bartholdson J, Wright GJ, Ober EA. EphrinB1/EphB3b Coordinate Bidirectional Epithelial-Mesenchymal Interactions Controlling Liver Morphogenesis and Laterality. Dev Cell. 2016;39(3):316-28. doi:10.1016/j.devcel.2016.10.009.

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