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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
A zebrafish model of Poikiloderma with Neutropenia recapitulates the human syndrome hallmarks and traces back neutropenia to the myeloid progenitor
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Citation:
Sci Rep. 2015;5:15814. doi:10.1038/srep15814 Epub:
Not Epub Abstract:
Poikiloderma with Neutropenia (PN) is an autosomal recessive genodermatosis characterized by early-onset poikiloderma,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Colombo EA, Carra S, Fontana L, Bresciani E, Cotelli F, Larizza L. A zebrafish model of Poikiloderma with Neutropenia recapitulates the human syndrome hallmarks and traces back neutropenia to the myeloid progenitor. Sci Rep. 2015;5:15814. doi:10.1038/srep15814. |
Neurogenesis in sea urchin embryos and the diversity of deuterostome neurogenic mechanisms
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Citation:
Development. 2015 Oct 28. pii: dev.124503. [Epub ahead of print] Epub:
Yes Abstract:
A single origin to the diverse mechanisms of metazoan neurogenesis is suggested by the involvement of common signaling... Delivery Method:
microinjection Organism or Cell Type:
sea urchin Citation Extract: Garner S, Zysk I, Byrne G, Kramer M, Moller D, Taylor V, Burke RD. Neurogenesis in sea urchin embryos and the diversity of deuterostome neurogenic mechanisms. Development. 2015 Oct 28. pii: dev.124503. [Epub ahead of print]. |
Production of reproductively sterile fish by a non-transgenic gene silencing technology
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Citation:
Sci Rep. 2015 Oct 29;5:15822. doi: 10.1038/srep15822 Epub:
Not Epub Abstract:
We developed a novel bath-immersion technology to produce large numbers of infertile fish. As seafood consumption shifts from... Delivery Method:
Vivo-Morpholino bathing Organism or Cell Type:
zebrafish Citation Extract: Wong TT, Zohar Y. Production of reproductively sterile fish by a non-transgenic gene silencing technology. Sci Rep. 2015 Oct 29;5:15822. doi: 10.1038/srep15822. |
Gene Interference with Morpholinos in a Gold Nanoparticle-Based Delivery Platform in Rat PC12 Cells
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Citation:
J Biomed Nanotechnol. 2015 Dec;11(12):2111-23 Epub:
Not Epub Abstract:
For the first time the efficiency of gene knockdown of the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor... Delivery Method:
nanoparticle Organism or Cell Type:
cell culture: rat PC12 Citation Extract: Deng W, Farnham MM, Goldys EM, Mohammed S, Pilowsky PM. Gene Interference with Morpholinos in a Gold Nanoparticle-Based Delivery Platform in Rat PC12 Cells. J Biomed Nanotechnol. 2015 Dec;11(12):2111-23. |
klf2ash317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes
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Citation:
PLoS One. 2015 Oct 27;10(10):e0141611. doi: 10.1371/journal.pone.0141611. eCollection 2015 Epub:
Not Epub Abstract:
INTRODUCTION AND OBJECTIVES: The zinc-finger transcription factor Krϋppel-like factor 2 (KLF2) transduces blood flow into... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Novodvorsky P, Watson O, Gray C, Wilkinson RN, Reeve S, Smythe C, Beniston R, Plant K, Maguire R, M K Rothman A, Elworthy S, van Eeden FJ, Chico TJ. klf2ash317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes. PLoS One. 2015 Oct 27;10(10):e0141611. doi: 10.1371/journal.pone.0141611. eCollection 2015. |
Down-regulation of msrb3 and destruction of normal auditory system development through hair cell apoptosis in zebrafish
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Citation:
Int J Dev Biol. 2015;59(4-5-6):195-203 Epub:
Not Epub Abstract:
Hearing defects can significantly influence quality of life for those who experience them. At this time, 177 deafness genes... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shen X, Liu F, Wang Y, Wang H, Ma J, Xia W, Zhang J, Jiang N, Sun S, Wang X, Ma D. Down-regulation of msrb3 and destruction of normal auditory system development through hair cell apoptosis in zebrafish. Int J Dev Biol. 2015;59(4-5-6):195-203. |
Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone
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Citation:
J Physiol. 2015 Oct 27. doi: 10.1113/JP271286. [Epub ahead of print] Epub:
Yes Abstract:
KEY POINTS: KCNE4 alters the biophysical properties and cellular localisation of Kv7.4. KCNE4 is expressed in a variety of... Delivery Method:
Lipofectamine 2000 Citation Extract: Jepps TA, Carr G, Lundegaard PR, Olesen SP, Greenwood IA. Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone. J Physiol. 2015 Oct 27. doi: 10.1113/JP271286. [Epub ahead of print]. |
CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base
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Citation:
Nat Cell Biol. 2013 Jun;15(6):591-601. doi: 10.1038/ncb2739. Epub 2013 May 5 Epub:
Not Epub Abstract:
The transition zone is a specialized compartment found at the base of cilia, adjacent to the centriole distal end, where... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang WJ, Tay HG, Soni R, Perumal GS, Goll MG, Macaluso FP, Asara JM, Amack JD, Tsou MF. CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base. Nat Cell Biol. 2013 Jun;15(6):591-601. doi: 10.1038/ncb2739. Epub 2013 May 5. |
Morpholinos: Antisense and Sensibility
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Citation:
Dev Cell. 2015;35(2):145-9. doi:10.1016/j.devcel.2015.09.017 Epub:
Not Epub Abstract:
For over 15 years, antisense morpholino oligonucleotides (MOs) have allowed developmental biologists to make key discoveries... Citation Extract: Blum M, De Robertis EM, Wallingford JB, Niehrs C. Morpholinos: Antisense and Sensibility. Dev Cell. 2015;35(2):145-9. doi:10.1016/j.devcel.2015.09.017. |
Lsh Is Essential for Maintaining Global DNA Methylation Levels in Amphibia and Fish and Interacts Directly with Dnmt1
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Citation:
Biomed Res Int. 2015;2015:740637. doi: 10.1155/2015/740637. Epub 2015 Sep 28 Epub:
Not Epub Abstract:
Eukaryotic genomes are methylated at cytosine bases in the context of CpG dinucleotides, a pattern which is maintained through... Delivery Method:
microinjection Organism or Cell Type:
zebrafish & Xenopus laevis Citation Extract: Dunican DS, Pennings S, Meehan RR. Lsh Is Essential for Maintaining Global DNA Methylation Levels in Amphibia and Fish and Interacts Directly with Dnmt1. Biomed Res Int. 2015;2015:740637. doi: 10.1155/2015/740637. Epub 2015 Sep 28. |