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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Glucocerebrosidase deficiency in zebrafish affects primary bone ossification through increased oxidative stress and reduced Wnt/β-catenin signaling
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Citation:
Hum Mol Genet. 2014 Oct 17. pii: ddu538. [Epub ahead of print] Epub:
Yes Abstract:
Loss of lysosomal glucocerebrosidase (GBA1) function is responsible for several organ defects, including skeletal abnormalities... Organism or Cell Type:
zebrafish Citation Extract: Zancan I, Bellesso S, Costa R, Salvalaio M, Stroppiano M, Hammond C, Argenton F, Filocamo M, Moro E. Glucocerebrosidase deficiency in zebrafish affects primary bone ossification through increased oxidative stress and reduced Wnt/β-catenin signaling. Hum Mol Genet. 2014 Oct 17. pii: ddu538. [Epub ahead of print]. |
A Novel TGFβ Modulator that Uncouples R-Smad/I-Smad-Mediated Negative Feedback from R-Smad/Ligand-Driven Positive Feedback
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Citation:
PLoS Biol. 2015;13(2):e1002051. doi:10.1371/journal.pbio.1002051 Epub:
Not Epub Abstract:
As some of the most widely utilised intercellular signalling molecules, transforming growth factor β (TGFβ) superfamily members... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gu W, Monteiro R, Zuo J, Simões FC, Martella A, Andrieu-Soler C, Grosveld F, Sauka-Spengler T, Patient R. A Novel TGFβ Modulator that Uncouples R-Smad/I-Smad-Mediated Negative Feedback from R-Smad/Ligand-Driven Positive Feedback. PLoS Biol. 2015;13(2):e1002051. doi:10.1371/journal.pbio.1002051. |
CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development
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Citation:
Cell Res. 2015 Feb 6. doi: 10.1038/cr.2015.15. [Epub ahead of print] Epub:
Yes Abstract:
Angiogenesis, a process that newly-formed blood vessels sprout from pre-existing ones, is vital for vertebrate development... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tu T, Zhang C, Yan H, Luo Y, Kong R, Wen P, Ye Z, Chen J, Feng J, Liu F, Wu JY, Yan X. CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development. Cell Res. 2015 Feb 6. doi: 10.1038/cr.2015.15. [Epub ahead of print]. |
Microtubule-associated protein tau promotes neuronal class II β-tubulin microtubule formation and axon elongation in embryonic Xenopus laevis
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Citation:
Eur J Neurosci. 2015 Feb 6. doi: 10.1111/ejn.12848. [Epub ahead of print] Epub:
Not Epub Abstract:
Compared with its roles in neurodegeneration, much less is known about microtubule-associated protein tau's normal... Organism or Cell Type:
Xenopus laevis Citation Extract: Liu Y, Wang C, Destin G, Szaro BG. Microtubule-associated protein tau promotes neuronal class II β-tubulin microtubule formation and axon elongation in embryonic Xenopus laevis. Eur J Neurosci. 2015 Feb 6. doi: 10.1111/ejn.12848. [Epub ahead of print]. |
A Dicer-miR-107 Interaction Regulates Biogenesis of Specific miRNAs Crucial for Neurogenesis
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Citation:
Dev Cell. 2015;[Epub ahead of print] doi:10.1016/j.devcel.2014.12.013 Epub:
Yes Abstract:
Dicer controls the biogenesis of microRNAs (miRNAs) and is essential for neurogenesis. Recent reports show that the levels and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ristori E, Lopez-Ramirez MA, Narayanan A, Hill-Teran G, Moro A, Calvo C-F, Thomas J-L, Nicoli S. A Dicer-miR-107 Interaction Regulates Biogenesis of Specific miRNAs Crucial for Neurogenesis. Dev Cell. 2015;[Epub ahead of print] doi:10.1016/j.devcel.2014.12.013. |
High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides
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Citation:
Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv060 Epub:
Yes Abstract:
The therapeutic use of antisense and siRNA oligonucleotides has been constrained by the limited ability of these membrane-... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: A375 melanoma cells Citation Extract: Yang B, Ming X, Cao C, Laing B, Yuan A, Porter MA, Hull-Ryde EA, Maddry J, Suto M, Janzen WP, Juliano RL. High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides. Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv060 . |
PTPMT1 Inhibition Lowers Glucose through Succinate Dehydrogenase Phosphorylation
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Citation:
Cell Rep. 2015;[Epub ahead of print] doi:/10.1016/j.celrep.2015.01.010 Epub:
Yes Abstract:
Virtually all organisms seek to maximize fitness by matching fuel availability with energy expenditure. In vertebrates, glucose... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nath AK, Ryu JH, Jin YN, Roberts LD, Dejam A, Gerszten RE, Peterson RT. PTPMT1 Inhibition Lowers Glucose through Succinate Dehydrogenase Phosphorylation. Cell Rep. 2015;[Epub ahead of print] doi:/10.1016/j.celrep.2015.01.010. |
cnrip1 is a regulator of eye and neural development in Xenopus laevis
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Citation:
Genes Cells. 2015 Feb 5. doi: 10.1111/gtc.12225. [Epub ahead of print] Epub:
Yes Abstract:
Cannabinoid receptor interacting protein 1 (CNRIP1), which has been originally identified as the binding partner of cannabinoid... Organism or Cell Type:
Xenopus laevis Citation Extract: Zheng X, Suzuki T, Takahashi C, Nishida E, Kusakabe M. cnrip1 is a regulator of eye and neural development in Xenopus laevis. Genes Cells. 2015 Feb 5. doi: 10.1111/gtc.12225. [Epub ahead of print]. |
FGF signalling restricts haematopoietic stem cell specification via modulation of the BMP pathway
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Citation:
Nat Commun. 2014 Nov 27;5:5588. doi: 10.1038/ncomms6588 Epub:
Not Epub Abstract:
Haematopoietic stem cells (HSCs) are produced during embryogenesis from the floor of the dorsal aorta. The localization of HSCs... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pouget C, Peterkin T, Simões FC, Lee Y, Traver D, Patient R. FGF signalling restricts haematopoietic stem cell specification via modulation of the BMP pathway. Nat Commun. 2014 Nov 27;5:5588. doi: 10.1038/ncomms6588. |
Disruption of CLPB is associated with congenital microcephaly, severe encephalopathy and 3-methylglutaconic aciduria
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Citation:
J Med Genet. 2015 Feb 3. pii: jmedgenet-2014-102952. doi: 10.1136/jmedgenet-2014-102952. [Epub ahead of print] Epub:
Not Epub Abstract:
BACKGROUND: The heterogeneous group of 3-methylglutaconic aciduria disorders includes several inborn errors of metabolism that... Organism or Cell Type:
zebrafish Citation Extract: Capo-Chichi JM, Boissel S, Brustein E, Pickles S, Fallet-Bianco C, Nassif C, Patry L, Dobrzeniecka S, Liao M, Labuda D, Samuels ME, Hamdan FF, Velde CV, Rouleau GA, Drapeau P, Michaud JL. Disruption of CLPB is associated with congenital microcephaly, severe encephalopathy and 3-methylglutaconic aciduria. J Med Genet. 2015 Feb 3. pii: jmedgenet-2014-102952. doi: 10.1136/jmedgenet-2014-102952. [Epub ahead of print]. |