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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
A comparison of two cellular delivery mechanisms for small interfering RNA
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Citation:
Physiol Rep. 2015 Feb 3;3(2). pii: e12286. doi: 10.14814/phy2.12286. Print 2015 Feb 1 Epub:
Not Epub Abstract:
Cellular delivery of small interfering RNAs to target cells of a tissue has the potential to travel by two intercellular... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HeLaCx43 & HEK293 Citation Extract: Valiunas V, Wang HZ, Li L, Gordon C, Valiuniene L, Cohen IS, Brink PR. A comparison of two cellular delivery mechanisms for small interfering RNA. Physiol Rep. 2015 Feb 3;3(2). pii: e12286. doi: 10.14814/phy2.12286. Print 2015 Feb 1. |
Disruption of KATP channel expression in skeletal muscle by targeted oligonucleotide delivery promotes activity-linked thermogenesis
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Citation:
Mol Ther. 2015 Apr;23(4):707-16. doi: 10.1038/mt.2015.21. Epub 2015 Feb 4. Epub:
Yes Abstract:
Despite the medical, social and economic impact of obesity, only a few therapeutic options, focused largely on reducing caloric... Delivery Method:
Vivo-Morpholino Citation Extract: Koganti SR, Zhu Z, Subbotina E, Gao Z, Sierra A, Proenza M, Yang L, Alekseev A, Hodgson-Zingman D, Zingman L. Disruption of KATP channel expression in skeletal muscle by targeted oligonucleotide delivery promotes activity-linked thermogenesis. Mol Ther. 2015 Apr;23(4):707-16. doi: 10.1038/mt.2015.21. Epub 2015 Feb 4.. |
Long-Term Efficacy of Systemic Multiexon Skipping Targeting Dystrophin Exons 45-55 With a Cocktail of Vivo-Morpholinos in Mdx52 Mice
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Citation:
Mol Ther Nucleic Acids. 2015 Feb 3;4:e225. doi: 10.1038/mtna.2014.76 Epub:
Not Epub Abstract:
Antisense-mediated exon skipping, which can restore the reading frame, is a most promising therapeutic approach for Duchenne... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mdx52 mice Citation Extract: Echigoya Y, Aoki Y, Miskew B, Panesar D, Touznik A, Nagata T, Tanihata J, Nakamura A, Nagaraju K, Yokota T. Long-Term Efficacy of Systemic Multiexon Skipping Targeting Dystrophin Exons 45-55 With a Cocktail of Vivo-Morpholinos in Mdx52 Mice. Mol Ther Nucleic Acids. 2015 Feb 3;4:e225. doi: 10.1038/mtna.2014.76. |
NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms
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Citation:
Proc Natl Acad Sci U S A. 2015 Jan 20. pii: 201417290. [Epub ahead of print] Epub:
Yes Abstract:
Nicotinamide adenine dinucleotide phosphate (NADP) is a critical cofactor during metabolism, calcium signaling, and oxidative... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Love NR, Pollak N, Dölle C, Niere M, Chen Y, Oliveri P, Amaya E, Patel S, Ziegler M. NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms. Proc Natl Acad Sci U S A. 2015 Jan 20. pii: 201417290. [Epub ahead of print]. |
Loss of wwox expression in zebrafish embryos causes edema and alters Ca2+ dynamics
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Citation:
PeerJ. 2015;3:e727 doi:10.7717/peerj.727 Epub:
Not Epub Abstract:
We investigated the role of the WW domain-containing oxidoreductase (wwox) gene in the embryonic development of zebrafish, with... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tsuruwaka Y, Konishi M, Shimada E. Loss of wwox expression in zebrafish embryos causes edema and alters Ca2+ dynamics. PeerJ. 2015;3:e727 doi:10.7717/peerj.727. |
MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells
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Citation:
Proc Natl Acad Sci U S A. 2015 Jan 20. pii: 201424576. [Epub ahead of print] Epub:
Yes Abstract:
Canonical Wnt signaling plays an important role in development and disease, regulating transcription of target genes and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Ploper D, Taelman VF, Robert L, Perez BS, Titz B, Chen HW, Graeber TG, von Euw E, Ribas A, De Robertis EM. MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells. Proc Natl Acad Sci U S A. 2015 Jan 20. pii: 201424576. [Epub ahead of print]. |
Functional variants of POC5 identified in patients with idiopathic scoliosis
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Citation:
J Clin Invest. 2015 Feb 2. pii: 77262. doi: 10.1172/JCI77262. [Epub ahead of print] Epub:
Yes Abstract:
Idiopathic scoliosis (IS) is a spine deformity that affects approximately 3% of the population. The underlying causes of IS are... Organism or Cell Type:
zebrafish Citation Extract: Patten SA, Margaritte-Jeannin P, Bernard JC, Alix E, Labalme A, Besson A, Girard SL, Fendri K, Fraisse N, Biot B, Poizat C, Campan-Fournier A, Abelin-Genevois K, Cunin V, Zaouter C, Liao M, Lamy R, Lesca G, Menassa R, Marcaillou C, Letexier M, Sanlaville D, Berard J, Rouleau GA, Clerget-Darpoux F, Drapeau P, Moldovan F, Edery P. Functional variants of POC5 identified in patients with idiopathic scoliosis. J Clin Invest. 2015 Feb 2. pii: 77262. doi: 10.1172/JCI77262. [Epub ahead of print]. |
Interception of host angiogenic signalling limits mycobacterial growth
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Citation:
Nature. 2015 Jan 29;517(7536):612-5. doi: 10.1038/nature13967. Epub 2014 Nov 24 Epub:
Not Epub Abstract:
Pathogenic mycobacteria induce the formation of complex cellular aggregates called granulomas that are the hallmark of... Organism or Cell Type:
zebrafish Citation Extract: Oehlers SH, Cronan MR, Scott NR, Thomas MI, Okuda KS, Walton EM, Beerman RW, Crosier PS, Tobin DM. Interception of host angiogenic signalling limits mycobacterial growth. Nature. 2015 Jan 29;517(7536):612-5. doi: 10.1038/nature13967. Epub 2014 Nov 24. |
Regulation of β1 Integrin-Klf2-Mediated Angiogenesis by CCM Proteins
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Citation:
Dev Cell. 2015 Jan 26;32(2):181-90. doi: 10.1016/j.devcel.2014.12.016 Epub:
Not Epub Abstract:
Mechanotransduction pathways are activated in response to biophysical stimuli during the development or homeostasis of organs... Organism or Cell Type:
zebrafish Citation Extract: Renz M, Otten C, Faurobert E, Rudolph F, Zhu Y, Boulday G, Duchene J, Mickoleit M, Dietrich AC, Ramspacher C, Steed E, Manet-Dupé S, Benz A, Hassel D, Vermot J, Huisken J, Tournier-Lasserve E, Felbor U, Sure U, Albiges-Rizo C, Abdelilah-Seyfried S. Regulation of β1 Integrin-Klf2-Mediated Angiogenesis by CCM Proteins. Dev Cell. 2015 Jan 26;32(2):181-90. doi: 10.1016/j.devcel.2014.12.016. |
The Cerebral Cavernous Malformation Pathway Controls Cardiac Development via Regulation of Endocardial MEKK3 Signaling and KLF Expression
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Citation:
Dev Cell. 2015 Jan 26;32(2):168-80. doi: 10.1016/j.devcel.2014.12.009 Epub:
Not Epub Abstract:
The cerebral cavernous malformation (CCM) pathway is required in endothelial cells for normal cardiovascular development and to... Organism or Cell Type:
zebrafish Citation Extract: Zhou Z, Rawnsley DR, Goddard LM, Pan W, Cao XJ, Jakus Z, Zheng H, Yang J, Arthur JS, Whitehead KJ, Li D, Zhou B, Garcia BA, Zheng X, Kahn ML. The Cerebral Cavernous Malformation Pathway Controls Cardiac Development via Regulation of Endocardial MEKK3 Signaling and KLF Expression. Dev Cell. 2015 Jan 26;32(2):168-80. doi: 10.1016/j.devcel.2014.12.009. |