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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12390 scientific papers returned from the database with the search filters currently being used below.

C-terminal COOH of Integrin β1 Is Necessary for β1 Association with the Kindlin-2 Adapter Protein

Authors:
Fitzpatrick P, Shattil SJ, Ablooglu AJ
Citation:
J Biol Chem. 2014;289:11183-111. doi:10.1074/jbc.M113.535369
Epub:
Not Epub
Abstract:
Protein-protein interactions are driving forces in cellular processes. As a prime example, transmembrane integrins link...
Organism or Cell Type:
zebrafish
Citation Extract:
Fitzpatrick P, Shattil SJ, Ablooglu AJ. C-terminal COOH of Integrin β1 Is Necessary for β1 Association with the Kindlin-2 Adapter Protein. J Biol Chem. 2014;289:11183-111. doi:10.1074/jbc.M113.535369 .

Estrogen-related receptor γ is an in vivo receptor of bisphenol A

Authors:
Tohmé M, Prud’homme SM, Boulahtouf A, Samarut E, Brunet F, Bernard L, Bourguet W, Gibert Y, Balaguer P, Laudet V
Citation:
FASEB J. 2014;[Epubl ahead of print] doi:10.1096/fj.13-240465
Epub:
Yes
Abstract:
Bisphenol A (BPA) is an endocrine disruptor that displays estrogenic activity. Several reports suggest that BPA may have...
Organism or Cell Type:
zebrafish
Citation Extract:
Tohmé M, Prud’homme SM, Boulahtouf A, Samarut E, Brunet F, Bernard L, Bourguet W, Gibert Y, Balaguer P, Laudet V. Estrogen-related receptor γ is an in vivo receptor of bisphenol A. FASEB J. 2014;[Epubl ahead of print] doi:10.1096/fj.13-240465 .

Recurrent CNVs and SNVs at the NPHP1 Locus Contribute Pathogenic Alleles to Bardet-Biedl Syndrome

Authors:
Lindstrand A, Davis EE, Carvalho CMB, Pehlivan D, Willer JR, Tsai I-C, Ramanathan S, Zuppan C, Sabo A, Muzny D, Gibbs R, Liu P, Lewis RA, Banin E, Lupski JR, Clark R, Katsanis N
Citation:
Am J Hum Genet. 2014;[Epub ahead ofprint] doi:10.1016/j.ajhg.2014.03.017
Epub:
Yes
Abstract:
Homozygosity for a recurrent 290 kb deletion of NPHP1 is the most frequent cause of isolated nephronophthisis (NPHP) in humans...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lindstrand A, Davis EE, Carvalho CMB, Pehlivan D, Willer JR, Tsai I-C, Ramanathan S, Zuppan C, Sabo A, Muzny D, Gibbs R, Liu P, Lewis RA, Banin E, Lupski JR, Clark R, Katsanis N. Recurrent CNVs and SNVs at the NPHP1 Locus Contribute Pathogenic Alleles to Bardet-Biedl Syndrome. Am J Hum Genet. 2014;[Epub ahead ofprint] doi:10.1016/j.ajhg.2014.03.017.

Uracil-DNA Glycosylase is involved in DNA demethylation and required for embryonic development in the zebrafish embryo

Authors:
Wu D, Chen L, Sun Q, Wu X, Jia S, Meng A
Citation:
J Biol Chem. 2014 Apr 16. [Epub ahead of print]
Epub:
Yes
Abstract:
Uracil DNA glycosylase (Ung) is a component of base excision repair process and has the ability to remove uracil from U:G...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu D, Chen L, Sun Q, Wu X, Jia S, Meng A. Uracil-DNA Glycosylase is involved in DNA demethylation and required for embryonic development in the zebrafish embryo. J Biol Chem. 2014 Apr 16. [Epub ahead of print].

Activation of α2A-containing nicotinic acetylcholine receptors mediates nicotine-induced motor output in embryonic zebrafish

Authors:
Menelaou E, Udvadia AJ, Tanguay RL, Svoboda KR
Citation:
Eur J Neurosci. 2014 Apr 17. doi: 10.1111/ejn.12591. [Epub ahead of print]
Epub:
Not Epub
Abstract:
It is well established that cholinergic signaling has critical roles during central nervous system development. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Menelaou E, Udvadia AJ, Tanguay RL, Svoboda KR. Activation of α2A-containing nicotinic acetylcholine receptors mediates nicotine-induced motor output in embryonic zebrafish. Eur J Neurosci. 2014 Apr 17. doi: 10.1111/ejn.12591. [Epub ahead of print].

Synaptic Glutamate Spillover Due to Impaired Glutamate Uptake Mediates Heroin Relapse

Authors:
Shen H-w, Scofield MD, Boger H, Hensley M, Kalivas PW
Citation:
J Neurosci. 2014;34(16):5649-57 doi:10.1523/JNEUROSCI.4564-13.2014
Epub:
Not Epub
Abstract:
Reducing the enduring vulnerability to relapse is a therapeutic goal in treating drug addiction. Studies with animal models of...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Rat male Sprague Dawley
Citation Extract:
Shen H-w, Scofield MD, Boger H, Hensley M, Kalivas PW. Synaptic Glutamate Spillover Due to Impaired Glutamate Uptake Mediates Heroin Relapse. J Neurosci. 2014;34(16):5649-57 doi:10.1523/JNEUROSCI.4564-13.2014.

Inflammatory chemokines direct and restrict leukocyte migration within live tissues as glycan-bound gradients

Authors:
Sarris M, Masson JB, Maurin D, Van der Aa LM, Boudinot P, Lortat-Jacob H, Herbomel P
Citation:
Curr Biol. 2012 Dec 18;22(24):2375-82. doi: 10.1016/j.cub.2012.11.018. Epub 2012 Dec 6
Epub:
Not Epub
Abstract:
Chemokines are essential in many cell migration processes, including the recruitment of leukocytes to sites of infection. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sarris M, Masson JB, Maurin D, Van der Aa LM, Boudinot P, Lortat-Jacob H, Herbomel P. Inflammatory chemokines direct and restrict leukocyte migration within live tissues as glycan-bound gradients. Curr Biol. 2012 Dec 18;22(24):2375-82. doi: 10.1016/j.cub.2012.11.018. Epub 2012 Dec 6.

MicroRNAs are critical regulators of tuberous sclerosis complex and mTORC1 activity in the size control of the Xenopus kidney

Authors:
Romaker D, Kumar V, Cerqueira DM, Cox RM, Wessely O
Citation:
Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6335-40. doi: 10.1073/pnas.1320577111
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are major posttranscriptional regulators of a wide variety of biological processes. However, redundancy...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Romaker D, Kumar V, Cerqueira DM, Cox RM, Wessely O. MicroRNAs are critical regulators of tuberous sclerosis complex and mTORC1 activity in the size control of the Xenopus kidney. Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6335-40. doi: 10.1073/pnas.1320577111.

Near-Infrared-Light-Based Nano-Platform Boosts Endosomal Escape and Controls Gene Knockdown in Vivo

Authors:
Jayakumar MK, Bansal A, Huang K, Yao R, Li BN, Zhang Y
Citation:
ACS Nano. 2014 Apr 14. [Epub ahead of print]
Epub:
Yes
Abstract:
Current nanoparticle-based gene delivery techniques face two major limitations, namely, endosomal degradation and poor...
Delivery Method:
nanoparticle
Organism or Cell Type:
mouse
Citation Extract:
Jayakumar MK, Bansal A, Huang K, Yao R, Li BN, Zhang Y. Near-Infrared-Light-Based Nano-Platform Boosts Endosomal Escape and Controls Gene Knockdown in Vivo. ACS Nano. 2014 Apr 14. [Epub ahead of print].

Thymosin Beta4 Regulates Cardiac Valve Formation Via Endothelial-Mesenchymal Transformation in Zebrafish Embryos

Authors:
Shin SH, Lee S, Bae JS, Jee JG, Cha HJ, Lee YM
Citation:
Mol Cells. 2014 Apr 8. doi: 10.14348/molcells.2014.0003. [Epub ahead of print]
Epub:
Yes
Abstract:
Thymosin beta4 (TB4) has multiple functions in cellular response in processes as diverse as embryonic organ development and the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shin SH, Lee S, Bae JS, Jee JG, Cha HJ, Lee YM . Thymosin Beta4 Regulates Cardiac Valve Formation Via Endothelial-Mesenchymal Transformation in Zebrafish Embryos. Mol Cells. 2014 Apr 8. doi: 10.14348/molcells.2014.0003. [Epub ahead of print].

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