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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12390 scientific papers returned from the database with the search filters currently being used below.

Expression and function of transcription factor cMyb during cranial neural crest development

Authors:
Betancur P, Simões-Costa M, Sauka-Spengler T, Bronner ME
Citation:
Mech Dev. 2014;[Epub ahead of print] doi:10.1016/j.mod.2014.01.005
Epub:
Yes
Abstract:
The transcription factor cMyb has well known functions in vertebrate hematopoiesis, but little was known about its distribution...
Organism or Cell Type:
chick
Citation Extract:
Betancur P, Simões-Costa M, Sauka-Spengler T, Bronner ME. Expression and function of transcription factor cMyb during cranial neural crest development. Mech Dev. 2014;[Epub ahead of print] doi:10.1016/j.mod.2014.01.005.

The Heterochronic Genes lin-28a and lin-28b Play an Essential and Evolutionarily Conserved Role in Early Zebrafish Development

Authors:
Ouchi Y, Yamamoto J, Iwamoto T
Citation:
PLoS ONE. 2014;9(2):e88086. doi:10.1371/journal.pone.0088086
Epub:
Not Epub
Abstract:
The Caenorhabditis elegans heterochronic gene pathway, which consists of a set of regulatory genes, plays an important...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ouchi Y, Yamamoto J, Iwamoto T. The Heterochronic Genes lin-28a and lin-28b Play an Essential and Evolutionarily Conserved Role in Early Zebrafish Development. PLoS ONE. 2014;9(2):e88086. doi:10.1371/journal.pone.0088086.

Interdependence of Bad and Puma during Ionizing-Radiation-Induced Apoptosis

Authors:
Toruno C, Carbonneau S, Stewart RA, Jette C
Citation:
PLoS ONE. 2014;9(2):e88151. doi:10.1371/journal.pone.0088151
Epub:
Not Epub
Abstract:
Ionizing radiation (IR)-induced DNA double-strand breaks trigger an extensive cellular signaling response that involves the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Toruno C, Carbonneau S, Stewart RA, Jette C. Interdependence of Bad and Puma during Ionizing-Radiation-Induced Apoptosis. PLoS ONE. 2014;9(2):e88151. doi:10.1371/journal.pone.0088151.

Antisense suppression of donor splice site mutations in the dystrophin gene transcript

Authors:
Fletcher S, Meloni PL, Johnsen RD, Wong BL, Muntoni F, Wilton SD
Citation:
Mol Genet Genomic Med. 2013 Sep;1(3):162-73. doi: 10.1002/mgg3.19. Epub 2013 Jun 13
Epub:
Not Epub
Abstract:
We describe two donor splice site mutations, affecting dystrophin exons 16 and 45 that led to Duchenne muscular dystrophy (DMD...
Delivery Method:
peptide-linked
Organism or Cell Type:
Primary DMD human cells underwent forced myogenesis
Citation Extract:
Fletcher S, Meloni PL, Johnsen RD, Wong BL, Muntoni F, Wilton SD. Antisense suppression of donor splice site mutations in the dystrophin gene transcript. Mol Genet Genomic Med. 2013 Sep;1(3):162-73. doi: 10.1002/mgg3.19. Epub 2013 Jun 13.

Sept7b is essential for pronephric function and development of left-right asymmetry in zebrafish embryogenesis

Authors:
Dash SN, Lehtonen E, Wasik AA, Schepis A, Paavola J, Panula P, Nelson WJ, Lehtonen S
Citation:
J Cell Sci. 2014;[Epub ahead of print] doi:10.1242/jcs.138495
Epub:
Yes
Abstract:
The conserved septin family of filamentous small GTPases plays important roles in mitosis, cell migration, and cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dash SN, Lehtonen E, Wasik AA, Schepis A, Paavola J, Panula P, Nelson WJ, Lehtonen S. Sept7b is essential for pronephric function and development of left-right asymmetry in zebrafish embryogenesis. J Cell Sci. 2014;[Epub ahead of print] doi:10.1242/jcs.138495.

A network of epigenetic regulators guides developmental haematopoiesis in vivo

Authors:
Huang HT, Kathrein KL, Barton A, Gitlin Z, Huang YH, Ward TP, Hofmann O, Dibiase A, Song A, Tyekucheva S, Hide W, Zhou Y, Zon LI
Citation:
Nat Cell Biol. 2013 Dec;15(12):1516-25. doi: 10.1038/ncb2870. Epub 2013 Nov 17
Epub:
Not Epub
Abstract:
The initiation of cellular programs is orchestrated by key transcription factors and chromatin regulators that activate or...
Organism or Cell Type:
zebrafish
Citation Extract:
Huang HT, Kathrein KL, Barton A, Gitlin Z, Huang YH, Ward TP, Hofmann O, Dibiase A, Song A, Tyekucheva S, Hide W, Zhou Y, Zon LI . A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nat Cell Biol. 2013 Dec;15(12):1516-25. doi: 10.1038/ncb2870. Epub 2013 Nov 17.

Loss of FTO Antagonises Wnt Signaling and Leads to Developmental Defects Associated with Ciliopathies

Authors:
Osborn DPS, Roccasecca RM, McMurray F, Hernandez-Hernandez V, Mukherjee S, Barroso I, Stemple D, Cox R, Beales PL, Christou-Salvina S
Citation:
PLoS ONE 2014;9(2):e87662. doi:10.1371/journal.pone.0087662
Epub:
Not Epub
Abstract:
Common intronic variants in the Human fat mass and obesity-associated gene (FTO) are found to be associated with an increased...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Osborn DPS, Roccasecca RM, McMurray F, Hernandez-Hernandez V, Mukherjee S, Barroso I, Stemple D, Cox R, Beales PL, Christou-Salvina S. Loss of FTO Antagonises Wnt Signaling and Leads to Developmental Defects Associated with Ciliopathies. PLoS ONE 2014;9(2):e87662. doi:10.1371/journal.pone.0087662.

Genome-Wide Linkage, Exome Sequencing and Functional Analyses Identify ABCB6 as the Pathogenic Gene of Dyschromatosis Universalis Hereditaria

Authors:
Liu H, Li Y, Hung KKH, Wang N, Wang C, Chen X, Sheng D, Fu X, See K, Foo JN, Low H, Liany H, Irwan ID, Liu J, Yang B, Chen M, Yu Y, Yu G, Niu G, You J, Zhou Y, Ma S, Wang T, Yan X, Goh BK, Common JEA, Lane BE, Sun Y, Zhou G, Lu X, Wang Z, Tian H, Cao Y, Chen S, Liu Q, Liu J, Zhang F
Citation:
PLoS ONE 2014;9(2):e87250. doi:10.1371/journal.pone.0087250
Epub:
Not Epub
Abstract:
Background: As a genetic disorder of abnormal pigmentation, the molecular basis of dyschromatosis universalis hereditaria (DUH...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu H, Li Y, Hung KKH, Wang N, Wang C, Chen X, Sheng D, Fu X, See K, Foo JN, Low H, Liany H, Irwan ID, Liu J, Yang B, Chen M, Yu Y, Yu G, Niu G, You J, Zhou Y, Ma S, Wang T, Yan X, Goh BK, Common JEA, Lane BE, Sun Y, Zhou G, Lu X, Wang Z, Tian H, Cao Y, Chen S, Liu Q, Liu J, Zhang F. Genome-Wide Linkage, Exome Sequencing and Functional Analyses Identify ABCB6 as the Pathogenic Gene of Dyschromatosis Universalis Hereditaria. PLoS ONE 2014;9(2):e87250. doi:10.1371/journal.pone.0087250.

Molecular cloning and knockdown of galactocerebrosidase in zebrafish: New insights into the pathogenesis of Krabbe's disease

Authors:
Zizioli D, Guarienti M, Tobia C, Gariano G, Borsani G, Bresciani R, Ronca R, Giacopuzzi E, Preti A, Gaudenzi G, Belleri M, Di Salle E, Fabrias G, Casas J, Ribatti D, Monti E, Presta M
Citation:
Biochim Biophys Acta. 2014 Jan 24. pii: S0925-4439(14)00020-9. doi: 10.1016/j.bbadis.2014.01.008. [Epub ahead of print]
Epub:
Yes
Abstract:
The lysosomal hydrolase galactocerebrosidase (GALC) catalyzes the removal of galactose from galactosylceramide and from other...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zizioli D, Guarienti M, Tobia C, Gariano G, Borsani G, Bresciani R, Ronca R, Giacopuzzi E, Preti A, Gaudenzi G, Belleri M, Di Salle E, Fabrias G, Casas J, Ribatti D, Monti E, Presta M. Molecular cloning and knockdown of galactocerebrosidase in zebrafish: New insights into the pathogenesis of Krabbe's disease. Biochim Biophys Acta. 2014 Jan 24. pii: S0925-4439(14)00020-9. doi: 10.1016/j.bbadis.2014.01.008. [Epub ahead of print].

Knockdown of zebrafish blood vessel epicardial substance (Bves) results in incomplete retinal lamination

Authors:
Wu Y-C Chen R-F, Liu C-Y, Hu FR, Huang CJ, Wang I-J
Citation:
Sci World J. 2014;[Epub ahead of print] doi10.1155/2014/803718
Epub:
Yes
Abstract:
Cell polarity during eye development determines the normal retinal lamination and differentiation of photoreceptor cells in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu Y-C Chen R-F, Liu C-Y, Hu FR, Huang CJ, Wang I-J. Knockdown of zebrafish blood vessel epicardial substance (Bves) results in incomplete retinal lamination. Sci World J. 2014;[Epub ahead of print] doi10.1155/2014/803718.

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