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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12092 scientific papers returned from the database with the search filters currently being used below.

miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1

Authors:
Hwang-Verslues WW, Chang PH, Wei PC, Yang CY, Huang CK, Kuo WH, Shew JY, Chang KJ, Lee EY, Lee WH
Citation:
Oncogene. 2011 May 26;30(21):2463-74. doi: 10.1038/onc.2010.618. Epub 2011 Jan 24.
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are involved in tumorigenecity by regulating specific oncogenes and tumor suppressor genes, and their roles...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HEK 293
Citation Extract:
Hwang-Verslues WW, Chang PH, Wei PC, Yang CY, Huang CK, Kuo WH, Shew JY, Chang KJ, Lee EY, Lee WH. miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1. Oncogene. 2011 May 26;30(21):2463-74. doi: 10.1038/onc.2010.618. Epub 2011 Jan 24..

Molecular cloning and functional characterization of zebrafish ATM

Authors:
Imamura S, Kishi S
Citation:
Int J Biochem Cell Biol. 2005 May;37(5):1105-16.
Epub:
Not Epub
Abstract:
Ataxia-telangiectasia mutated (ATM) is the gene product mutated in ataxia-telangiectasia (A-T), which is an autosomal recessive...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Imamura S, Kishi S. Molecular cloning and functional characterization of zebrafish ATM. Int J Biochem Cell Biol. 2005 May;37(5):1105-16..

Morpholino phenocopies of the bmp2b/swirl and bmp7/snailhouse mutations

Authors:
Imai Y, Talbot WS
Citation:
Genesis. 2001 Jul;30(3):160-3
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Imai Y, Talbot WS. Morpholino phenocopies of the bmp2b/swirl and bmp7/snailhouse mutations. Genesis. 2001 Jul;30(3):160-3.

Multiple functions of a Zic-like gene in the differentiation of notochord, central nervous system and muscle in Ciona savignyi embryos

Authors:
Imai KS, Satou Y, Satoh N
Citation:
Development. 2002 Jun;129(11):2723-32
Epub:
Not Epub
Abstract:
Multiple functions of a Zic-like zinc finger transcription factor gene (Cs-ZicL) were identified in Ciona savignyi embryos....
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona savignyi
Citation Extract:
Imai KS, Satou Y, Satoh N. Multiple functions of a Zic-like gene in the differentiation of notochord, central nervous system and muscle in Ciona savignyi embryos. Development. 2002 Jun;129(11):2723-32.

Mutations in COX7B cause microphthalmia with linear skin lesions, an unconventional mitochondrial disease

Authors:
Indrieri A, van Rahden VA, Tiranti V, Morleo M, Iaconis D, Tammaro R, D'Amato I, Conte I, Maystadt I, Demuth S, Zvulunov A, Kutsche K, Zeviani M, Franco B
Citation:
Am J Hum Genet. 2012 Nov 2;91(5):942-9. doi: 10.1016/j.ajhg.2012.09.016
Epub:
Not Epub
Abstract:
Microphthalmia with linear skin lesions (MLS) is an X-linked dominant male-lethal disorder associated with mutations in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Indrieri A, van Rahden VA, Tiranti V, Morleo M, Iaconis D, Tammaro R, D'Amato I, Conte I, Maystadt I, Demuth S, Zvulunov A, Kutsche K, Zeviani M, Franco B. Mutations in COX7B cause microphthalmia with linear skin lesions, an unconventional mitochondrial disease. Am J Hum Genet. 2012 Nov 2;91(5):942-9. doi: 10.1016/j.ajhg.2012.09.016.

Myosin-X is required for cranial neural crest cell migration in Xenopus laevis

Authors:
Hwang YS, Luo T, Xu Y, Sargent TD
Citation:
Dev Dyn. 2009 Oct;238(10):2522-9. doi: 10.1002/dvdy.22077.
Epub:
Not Epub
Abstract:
Myosin-X (MyoX) belongs to a large family of unconventional, nonmuscle, actin-dependent motor proteins. We show that MyoX is...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hwang YS, Luo T, Xu Y, Sargent TD. Myosin-X is required for cranial neural crest cell migration in Xenopus laevis. Dev Dyn. 2009 Oct;238(10):2522-9. doi: 10.1002/dvdy.22077..

Nanobiopolymer for Direct Targeting and Inhibition of EGFR Expression in Triple Negative Breast Cancer

Authors:
Inoue S, Patil R, Portilla-Arias J, Ding H, Konda B, Espinoza A, Mongayt D, Markman JL, Elramsisy A, Phillips HW, Black KL, Holler E, Ljubimova JY
Citation:
PLoS ONE. 2012;7(2):e31070. doi:10.1371/journal.pone.0031070
Epub:
Not Epub
Abstract:
Treatment options for triple negative breast cancer (TNBC) are generally limited to cytotoxic chemotherapy. Recently, anti-...
Delivery Method:
in vivo: injection
Organism or Cell Type:
Mice, tumor model
Citation Extract:
Inoue S, Patil R, Portilla-Arias J, Ding H, Konda B, Espinoza A, Mongayt D, Markman JL, Elramsisy A, Phillips HW, Black KL, Holler E, Ljubimova JY. Nanobiopolymer for Direct Targeting and Inhibition of EGFR Expression in Triple Negative Breast Cancer. PLoS ONE. 2012;7(2):e31070. doi:10.1371/journal.pone.0031070.

Polymalic Acid–Based Nanobiopolymer Provides Efficient Systemic Breast Cancer Treatment by Inhibiting both HER2/neu Receptor Synthesis and Activity

Authors:
Inoue S, Ding H, Portilla-Arias J, Hu J, Konda B, Fujita M, Espinoza A, Suhane S, Riley M, Gates M, Patil R, Penichet ML, Ljubimov AV, Black KL, Holler E, Ljubimova JY
Citation:
Cancer Res. 2011 Feb 8;71(4):1454–64 [Epub ahead of print] doi:10.1158/0008-5472.CAN-10-3093
Epub:
Not Epub
Abstract:
Biodegradable nanopolymers are believed to offer great potential in cancer therapy. Here, we report the characterization of a...
Delivery Method:
Nanoparticle
Citation Extract:
Inoue S, Ding H, Portilla-Arias J, Hu J, Konda B, Fujita M, Espinoza A, Suhane S, Riley M, Gates M, Patil R, Penichet ML, Ljubimov AV, Black KL, Holler E, Ljubimova JY. Polymalic Acid–Based Nanobiopolymer Provides Efficient Systemic Breast Cancer Treatment by Inhibiting both HER2/neu Receptor Synthesis and Activity. Cancer Res. 2011 Feb 8;71(4):1454–64 [Epub ahead of print] doi:10.1158/0008-5472.CAN-10-3093.

Protective role of Cdc48 against neurodegeneration via Ubiquitin-proteasome system dysfunction during Zebrafish development

Authors:
Imamura S, Yabu Y, Yamashita M
Citation:
J Biol Chem. 2012 Jun 29;287(27):23047-56. doi: 10.1074/jbc.M111.332882. Epub 2012 May 1.
Epub:
Not Epub
Abstract:
Cell division cycle 48 (CDC48), a ubiquitin-dependent molecular chaperone, is thought to mediate a variety of degradative and...
Organism or Cell Type:
zebrafish
Citation Extract:
Imamura S, Yabu Y, Yamashita M. Protective role of Cdc48 against neurodegeneration via Ubiquitin-proteasome system dysfunction during Zebrafish development. J Biol Chem. 2012 Jun 29;287(27):23047-56. doi: 10.1074/jbc.M111.332882. Epub 2012 May 1..

Regulatory blueprint for a chordate embryo

Authors:
Imai KS, Levine M, Satoh N, Satou Y
Citation:
Science. 2006 May 26;312(5777):1183-7
Epub:
Not Epub
Abstract:
Ciona is an emerging model system for elucidating gene networks in development. Comprehensive in situ hybridization assays have...
Organism or Cell Type:
Ciona
Citation Extract:
Imai KS, Levine M, Satoh N, Satou Y. Regulatory blueprint for a chordate embryo. Science. 2006 May 26;312(5777):1183-7.

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