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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12185 scientific papers returned from the database with the search filters currently being used below.

Knockdown of SPARC leads to decreased cell-cell adhesion and lens cataracts during post-gastrula development in Xenopus laevis

Authors:
Huynh MH, Zhu SJ, Kollara A, Brown T, Winklbauer R, Ringuette M
Citation:
Dev Genes Evol. 2011 Mar;220(11-12):315-27. doi: 10.1007/s00427-010-0349-x. Epub 2011 Mar 8.
Epub:
Not Epub
Abstract:
SPARC is a multifunctional matricellular glycoprotein with complex, transient tissue distribution during embryonic development...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Huynh MH, Zhu SJ, Kollara A, Brown T, Winklbauer R, Ringuette M. Knockdown of SPARC leads to decreased cell-cell adhesion and lens cataracts during post-gastrula development in Xenopus laevis. Dev Genes Evol. 2011 Mar;220(11-12):315-27. doi: 10.1007/s00427-010-0349-x. Epub 2011 Mar 8..

MCAK regulates chromosome alignment but is not necessary for preventing aneuploidy in mouse oocyte meiosis I

Authors:
Illingworth C, Pirmadjid N, Serhal P, Howe K, Fitzharris G
Citation:
Development. 2010 Jul;137(13):2133-8. Epub 2010 May 26
Epub:
Not Epub
Abstract:
Errors in chromosome segregation in mammalian oocytes lead to aneuploid eggs that are developmentally compromised. In mitotic...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Illingworth C, Pirmadjid N, Serhal P, Howe K, Fitzharris G. MCAK regulates chromosome alignment but is not necessary for preventing aneuploidy in mouse oocyte meiosis I. Development. 2010 Jul;137(13):2133-8. Epub 2010 May 26.

Metalloprotease-Dependent Onset of Blood Circulation in Zebrafish

Authors:
Iida A, Sakaguchi K, Sato K, Sakurai H, Nishimura D, Iwaki A, Takeuchi M, Kobayashi M, Misaki K, Yonemura S, Kawahara A, Sehara-Fujisawa A
Citation:
Curr Biol. 2010 Jun 22;20(12):1110-6. doi: 10.1016/j.cub.2010.04.052. Epub 2010 Jun 3.
Epub:
Not Epub
Abstract:
The primitive blood circulation requires intravascular plasma flow [1]. However, it remains unclear whether the onset of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Iida A, Sakaguchi K, Sato K, Sakurai H, Nishimura D, Iwaki A, Takeuchi M, Kobayashi M, Misaki K, Yonemura S, Kawahara A, Sehara-Fujisawa A. Metalloprotease-Dependent Onset of Blood Circulation in Zebrafish. Curr Biol. 2010 Jun 22;20(12):1110-6. doi: 10.1016/j.cub.2010.04.052. Epub 2010 Jun 3..

miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1

Authors:
Hwang-Verslues WW, Chang PH, Wei PC, Yang CY, Huang CK, Kuo WH, Shew JY, Chang KJ, Lee EY, Lee WH
Citation:
Oncogene. 2011 May 26;30(21):2463-74. doi: 10.1038/onc.2010.618. Epub 2011 Jan 24.
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are involved in tumorigenecity by regulating specific oncogenes and tumor suppressor genes, and their roles...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HEK 293
Citation Extract:
Hwang-Verslues WW, Chang PH, Wei PC, Yang CY, Huang CK, Kuo WH, Shew JY, Chang KJ, Lee EY, Lee WH. miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1. Oncogene. 2011 May 26;30(21):2463-74. doi: 10.1038/onc.2010.618. Epub 2011 Jan 24..

Molecular cloning and functional characterization of zebrafish ATM

Authors:
Imamura S, Kishi S
Citation:
Int J Biochem Cell Biol. 2005 May;37(5):1105-16.
Epub:
Not Epub
Abstract:
Ataxia-telangiectasia mutated (ATM) is the gene product mutated in ataxia-telangiectasia (A-T), which is an autosomal recessive...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Imamura S, Kishi S. Molecular cloning and functional characterization of zebrafish ATM. Int J Biochem Cell Biol. 2005 May;37(5):1105-16..

Morpholino phenocopies of the bmp2b/swirl and bmp7/snailhouse mutations

Authors:
Imai Y, Talbot WS
Citation:
Genesis. 2001 Jul;30(3):160-3
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Imai Y, Talbot WS. Morpholino phenocopies of the bmp2b/swirl and bmp7/snailhouse mutations. Genesis. 2001 Jul;30(3):160-3.

Multiple functions of a Zic-like gene in the differentiation of notochord, central nervous system and muscle in Ciona savignyi embryos

Authors:
Imai KS, Satou Y, Satoh N
Citation:
Development. 2002 Jun;129(11):2723-32
Epub:
Not Epub
Abstract:
Multiple functions of a Zic-like zinc finger transcription factor gene (Cs-ZicL) were identified in Ciona savignyi embryos....
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona savignyi
Citation Extract:
Imai KS, Satou Y, Satoh N. Multiple functions of a Zic-like gene in the differentiation of notochord, central nervous system and muscle in Ciona savignyi embryos. Development. 2002 Jun;129(11):2723-32.

Mutations in COX7B cause microphthalmia with linear skin lesions, an unconventional mitochondrial disease

Authors:
Indrieri A, van Rahden VA, Tiranti V, Morleo M, Iaconis D, Tammaro R, D'Amato I, Conte I, Maystadt I, Demuth S, Zvulunov A, Kutsche K, Zeviani M, Franco B
Citation:
Am J Hum Genet. 2012 Nov 2;91(5):942-9. doi: 10.1016/j.ajhg.2012.09.016
Epub:
Not Epub
Abstract:
Microphthalmia with linear skin lesions (MLS) is an X-linked dominant male-lethal disorder associated with mutations in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Indrieri A, van Rahden VA, Tiranti V, Morleo M, Iaconis D, Tammaro R, D'Amato I, Conte I, Maystadt I, Demuth S, Zvulunov A, Kutsche K, Zeviani M, Franco B. Mutations in COX7B cause microphthalmia with linear skin lesions, an unconventional mitochondrial disease. Am J Hum Genet. 2012 Nov 2;91(5):942-9. doi: 10.1016/j.ajhg.2012.09.016.

Myosin-X is required for cranial neural crest cell migration in Xenopus laevis

Authors:
Hwang YS, Luo T, Xu Y, Sargent TD
Citation:
Dev Dyn. 2009 Oct;238(10):2522-9. doi: 10.1002/dvdy.22077.
Epub:
Not Epub
Abstract:
Myosin-X (MyoX) belongs to a large family of unconventional, nonmuscle, actin-dependent motor proteins. We show that MyoX is...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hwang YS, Luo T, Xu Y, Sargent TD. Myosin-X is required for cranial neural crest cell migration in Xenopus laevis. Dev Dyn. 2009 Oct;238(10):2522-9. doi: 10.1002/dvdy.22077..

Nanobiopolymer for Direct Targeting and Inhibition of EGFR Expression in Triple Negative Breast Cancer

Authors:
Inoue S, Patil R, Portilla-Arias J, Ding H, Konda B, Espinoza A, Mongayt D, Markman JL, Elramsisy A, Phillips HW, Black KL, Holler E, Ljubimova JY
Citation:
PLoS ONE. 2012;7(2):e31070. doi:10.1371/journal.pone.0031070
Epub:
Not Epub
Abstract:
Treatment options for triple negative breast cancer (TNBC) are generally limited to cytotoxic chemotherapy. Recently, anti-...
Delivery Method:
in vivo: injection
Organism or Cell Type:
Mice, tumor model
Citation Extract:
Inoue S, Patil R, Portilla-Arias J, Ding H, Konda B, Espinoza A, Mongayt D, Markman JL, Elramsisy A, Phillips HW, Black KL, Holler E, Ljubimova JY. Nanobiopolymer for Direct Targeting and Inhibition of EGFR Expression in Triple Negative Breast Cancer. PLoS ONE. 2012;7(2):e31070. doi:10.1371/journal.pone.0031070.

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