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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

Anti-infectives: Post-exposure antisense protection against lethal filoviruses?

Authors:
Flemming A
Citation:
Nat Rev Drug Discov. 2010 Oct;9(10):764-5
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
PMO+
Citation Extract:
Flemming A. Anti-infectives: Post-exposure antisense protection against lethal filoviruses?. Nat Rev Drug Discov. 2010 Oct;9(10):764-5.

Antisense suppression of donor splice site mutations in the dystrophin gene transcript

Authors:
Fletcher S, Meloni PL, Johnsen RD, Wong BL, Muntoni F, Wilton SD
Citation:
Mol Genet Genomic Med. 2013;[Epub ahead of print] doi:10.1002/mgg3.19
Epub:
Not Epub
Abstract:
We describe two donor splice site mutations, affecting dystrophin exons 16 and 45 that led to Duchenne muscular dystrophy (DMD...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: human primary fibroblasts and myogenic cells (subsequently differentiated)
Citation Extract:
Fletcher S, Meloni PL, Johnsen RD, Wong BL, Muntoni F, Wilton SD. Antisense suppression of donor splice site mutations in the dystrophin gene transcript. Mol Genet Genomic Med. 2013;[Epub ahead of print] doi:10.1002/mgg3.19.

Apoptotic and proliferative defects characterize ocular development in a microphthalmic BMP model

Authors:
French CR, Stach TR, March LD, Lehmann OJ, Waskiewicz AJ
Citation:
Invest Ophthalmol Vis Sci. 2013 Jun 4. doi:pii: iovs.13-11674v1. 10.1167/iovs.13-11674. [Epub ahead of print]
Epub:
Not Epub
Abstract:
PURPOSE: Vision is critically dependent on ocular size, which is regulated by environmental and genetic factors. Mutation of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
French CR, Stach TR, March LD, Lehmann OJ, Waskiewicz AJ. Apoptotic and proliferative defects characterize ocular development in a microphthalmic BMP model. Invest Ophthalmol Vis Sci. 2013 Jun 4. doi:pii: iovs.13-11674v1. 10.1167/iovs.13-11674. [Epub ahead of print].

Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish

Authors:
Flasse LC, Pirson JL, Stern DG, Von Berg V, Manfroid I, Peers B, Voz ML
Citation:
BMC Biol. 2013 Jul 8;11(1):78. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: NEUROG3 is a key regulator of pancreatic endocrine cell differentiation in mouse, essential for the generation of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Flasse LC, Pirson JL, Stern DG, Von Berg V, Manfroid I, Peers B, Voz ML. Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish. BMC Biol. 2013 Jul 8;11(1):78. [Epub ahead of print].

Base Excision Repair in Early Zebrafish Development: Evidence for DNA Polymerase Switching and Standby AP endonuclease Activity

Authors:
Fortier S, Yang X, Wang Y, Bennett RA, Strauss PR
Citation:
Biochemistry. 2009 Apr 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The base excision repair (BER) pathway recognizes and repairs most non-bulky lesions, uracil and abasic (AP) sites in DNA....
Organism or Cell Type:
zebrafish
Citation Extract:
Fortier S, Yang X, Wang Y, Bennett RA, Strauss PR. Base Excision Repair in Early Zebrafish Development: Evidence for DNA Polymerase Switching and Standby AP endonuclease Activity. Biochemistry. 2009 Apr 17. [Epub ahead of print].

Combinatorial activity of Flamingo proteins directs convergence and extension within the early zebrafish embryo via the planar cell polarity pathway

Authors:
Formstone CJ, Mason I
Citation:
Dev Biol. 2005 Jun 15;282(2):320-35.
Epub:
Not Epub
Abstract:
The seven-transmembrane protocadherin, Flamingo, functions in a number of processes during Drosophila development, including...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Formstone CJ, Mason I. Combinatorial activity of Flamingo proteins directs convergence and extension within the early zebrafish embryo via the planar cell polarity pathway. Dev Biol. 2005 Jun 15;282(2):320-35..

Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio)

Authors:
Flinn L, Mortiboys H, Volkmann K, Köster RW, Ingham PW, Bandmann O
Citation:
Brain. 2009 May 12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Currently, only symptomatic therapy is available for Parkinson's disease. The zebrafish is a vertebrate animal model...
Organism or Cell Type:
zebrafish
Citation Extract:
Flinn L, Mortiboys H, Volkmann K, Köster RW, Ingham PW, Bandmann O. Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio). Brain. 2009 May 12. [Epub ahead of print].

Convergent Extension Movements and Ciliary Function are Mediated by ofd1, A Zebrafish Orthologue of the Human Oral-Facial-Digital Type 1 Syndrome Gene

Authors:
Ferrante MI, Romio L, Castro S, Collins JE, Goulding DA, Stemple DL, Woolf AS, Wilson SW
Citation:
Hum Mol Genet. 2008 Oct 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
n humans, OFD1 is mutated in oral-facial-digital type I syndrome leading to prenatal death in hemizygous males and dysmorphic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ferrante MI, Romio L, Castro S, Collins JE, Goulding DA, Stemple DL, Woolf AS, Wilson SW. Convergent Extension Movements and Ciliary Function are Mediated by ofd1, A Zebrafish Orthologue of the Human Oral-Facial-Digital Type 1 Syndrome Gene. Hum Mol Genet. 2008 Oct 29. [Epub ahead of print].

Cystein-serine-rich nuclear protein 1, Axud1/Csrnp1, is essential for cephalic neural progenitor proliferation and survival in zebrafish

Authors:
Feijóo CG, Sarrazin AF, Allende ML, Glavic A
Citation:
Dev Dyn. 2009 Jun 19. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The CSRNP (cystein-serine-rich nuclear protein) family has been conserved from Drosophila to human. Although knockout mice for...
Organism or Cell Type:
zebrafish
Citation Extract:
Feijóo CG, Sarrazin AF, Allende ML, Glavic A. Cystein-serine-rich nuclear protein 1, Axud1/Csrnp1, is essential for cephalic neural progenitor proliferation and survival in zebrafish. Dev Dyn. 2009 Jun 19. [Epub ahead of print].

Dhrs3a Regulates Retinoic Acid Biosynthesis through a Feedback Inhibition Mechanism

Authors:
Feng L, Hernandez RE, Waxman JS, Yelon D, Moens CB
Citation:
Dev Biol. 2009 Oct 26. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Retinoic acid (RA) is an important developmental signaling molecule responsible for the patterning of multiple vertebrate...
Organism or Cell Type:
zebrafish
Citation Extract:
Feng L, Hernandez RE, Waxman JS, Yelon D, Moens CB. Dhrs3a Regulates Retinoic Acid Biosynthesis through a Feedback Inhibition Mechanism. Dev Biol. 2009 Oct 26. [Epub ahead of print].

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