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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12067 scientific papers returned from the database with the search filters currently being used below.

Morphants: a new systematic vertebrate functional genomics approach

Authors:
Ekker SC
Citation:
Yeast 2000 Dec;17(4):302-306
Epub:
Not Epub
Abstract:
The vertebrate genome contains a predicted 50 000-100 000 genes, many of unknown function. The recent development of morpholino...
Delivery Method:
not applicable
Organism or Cell Type:
zebrafish
Citation Extract:
Ekker SC. Morphants: a new systematic vertebrate functional genomics approach. Yeast 2000 Dec;17(4):302-306.

Morpholino Antisense Oligonucleotide-Mediated Gene Knockdown During Thymocyte Development Reveals Role for Runx3 Transcription Factor in CD4 Silencing During Development of CD4(-)/CD8(+) Thymocyte

Authors:
Ehlers M, Laule-Kilian K, Petter M, Aldrian CJ, Grueter B, Wurch A, Yoshida N, Watanabe T, Satake M, Steimle V
Citation:
J Immunol. 2003 Oct 1;171(7):3594-3604
Epub:
Not Epub
Abstract:
During thymic T cell development, immature CD4(+)/CD8(+) thymocytes develop into either CD4(+)/CD8(-) helper or CD4(-)/CD8(+)...
Delivery Method:
culture: Incubation & free uptake
Organism or Cell Type:
cell culture: immature thymocytes
Citation Extract:
Ehlers M, Laule-Kilian K, Petter M, Aldrian CJ, Grueter B, Wurch A, Yoshida N, Watanabe T, Satake M, Steimle V. Morpholino Antisense Oligonucleotide-Mediated Gene Knockdown During Thymocyte Development Reveals Role for Runx3 Transcription Factor in CD4 Silencing During Development of CD4(-)/CD8(+) Thymocyte. J Immunol. 2003 Oct 1;171(7):3594-3604.

mpeg1 promoter transgenes direct macrophage-lineage expression in zebrafish

Authors:
Ellett F, Pase L, Hayman JW, Andrianopoulos A, Lieschke GJ
Citation:
Blood. 2011 Jan 27;117(4):e49-56. Epub 2010 Nov 17
Epub:
Not Epub
Abstract:
Macrophages and neutrophils play important roles during the innate immune response, phagocytosing invading microbes and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ellett F, Pase L, Hayman JW, Andrianopoulos A, Lieschke GJ. mpeg1 promoter transgenes direct macrophage-lineage expression in zebrafish. Blood. 2011 Jan 27;117(4):e49-56. Epub 2010 Nov 17.

Neural guidance molecules regulate vascular remodeling and vessel navigation.

Authors:
Eichmann A, Makinen T, Alitalo K.
Citation:
Genes Dev. 2005 May 1;19(9):1013-21.
Epub:
Not Epub
Abstract:
The development of the embryonic blood vascular and lymphatic systems requires the coordinated action of several transcription...
Delivery Method:
not applicable
Organism or Cell Type:
zebrafish
Citation Extract:
Eichmann A, Makinen T, Alitalo K.. Neural guidance molecules regulate vascular remodeling and vessel navigation.. Genes Dev. 2005 May 1;19(9):1013-21..

Nodal-mediated epigenesis requires dynamin-mediated endocytosis

Authors:
Ertl RP, Robertson AJ, Saunders D, Coffman JA
Citation:
Dev Dyn. 2011 Mar;240(3):704-11. doi: 10.1002/dvdy.22557. Epub 2011 Feb 8
Epub:
Not Epub
Abstract:
Nodal proteins are diffusible morphogens that drive pattern formation via short-range feedback activation coupled to long-range...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Ertl RP, Robertson AJ, Saunders D, Coffman JA. Nodal-mediated epigenesis requires dynamin-mediated endocytosis. Dev Dyn. 2011 Mar;240(3):704-11. doi: 10.1002/dvdy.22557. Epub 2011 Feb 8.

Nonconventional antisense in zebrafish for functional genomics applications

Authors:
Ekker SC
Citation:
Methods Cell Biol. 2004;77:121-36
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ekker SC. Nonconventional antisense in zebrafish for functional genomics applications. Methods Cell Biol. 2004;77:121-36.

Overlapping functions of Cdx1, Cdx2, and Cdx4 in the development of the amphibian Xenopus tropicalis

Authors:
Faas L, Isaacs HV
Citation:
Dev Dyn. 2009 Mar 19;238(4):835-852. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Using Xenopus tropicalis, we present the first analysis of the developmental effects that result from knocking down the...
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Faas L, Isaacs HV. Overlapping functions of Cdx1, Cdx2, and Cdx4 in the development of the amphibian Xenopus tropicalis. Dev Dyn. 2009 Mar 19;238(4):835-852. [Epub ahead of print].

Pbx proteins cooperate with Engrailed to pattern the midbrain-hindbrain and diencephalic-mesencephalic boundaries

Authors:
Erickson T, Scholpp S, Brand M, Moens CB, Waskiewicz AJ
Citation:
Dev Biol. 2007 Jan 15;301(2):504-17. Epub 2006 Aug 10
Epub:
Not Epub
Abstract:
Pbx proteins are a family of TALE-class transcription factors that are well characterized as Hox co-factors acting to impart...
Organism or Cell Type:
zebrafish
Citation Extract:
Erickson T, Scholpp S, Brand M, Moens CB, Waskiewicz AJ. Pbx proteins cooperate with Engrailed to pattern the midbrain-hindbrain and diencephalic-mesencephalic boundaries. Dev Biol. 2007 Jan 15;301(2):504-17. Epub 2006 Aug 10.

PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome

Authors:
Ebermann I, Phillips JB, Liebau MC, Koenekoop RK, Schermer B, Lopez I, Schäfer E, Roux AF, Dafinger C, Bernd A, Zrenner E, Claustres M, Blanco B, Nürnberg G, Nürnberg P, Ruland R, Westerfield M, Benzing T, Bolz HJ
Citation:
J Clin Invest. 2010 May 3. pii: 39715. doi: 10.1172/JCI39715. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Usher syndrome is a genetically heterogeneous recessive disease characterized by hearing loss and retinitis pigmentosa (RP). It...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ebermann I, Phillips JB, Liebau MC, Koenekoop RK, Schermer B, Lopez I, Schäfer E, Roux AF, Dafinger C, Bernd A, Zrenner E, Claustres M, Blanco B, Nürnberg G, Nürnberg P, Ruland R, Westerfield M, Benzing T, Bolz HJ. PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome. J Clin Invest. 2010 May 3. pii: 39715. doi: 10.1172/JCI39715. [Epub ahead of print].

Phox2b function in the enteric nervous system is conserved in zebrafish and is sox10-dependent

Authors:
Elworthy S, Pinto JP, Pettifer A, Cancela ML, Kelsh RN
Citation:
Mech Dev. 2005 May;122(5):659-69.
Epub:
Not Epub
Abstract:
Zebrafish lacking functional sox10 have defects in non-ectomesenchymal neural crest derivatives including the enteric nervous...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Elworthy S, Pinto JP, Pettifer A, Cancela ML, Kelsh RN. Phox2b function in the enteric nervous system is conserved in zebrafish and is sox10-dependent. Mech Dev. 2005 May;122(5):659-69..

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