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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12092 scientific papers returned from the database with the search filters currently being used below.

Nodal signaling is required for closure of the anterior neural tube in zebrafish

Authors:
Aquilina-Beck A, Ilagan K, Liu Q, Liang JO
Citation:
BMC Dev Biol. 2007 Nov 8;7(1):126 [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: Nodals are secreted signaling proteins with many roles in vertebrate development. Here, we identify a new...
Organism or Cell Type:
zebrafish
Citation Extract:
Aquilina-Beck A, Ilagan K, Liu Q, Liang JO. Nodal signaling is required for closure of the anterior neural tube in zebrafish. BMC Dev Biol. 2007 Nov 8;7(1):126 [Epub ahead of print] .

Notch destabilises maternal β-catenin and restricts dorsal-anterior development in Xenopus

Authors:
Acosta H, López SL, Revinski DR, Carrasco AE
Citation:
Development. 2011 June 15;138:2567-79. doi: 10.1242/dev.061143
Epub:
Not Epub
Abstract:
The blastula chordin- and noggin-expressing centre (BCNE) is the predecessor of the Spemann-Mangold's organiser and also...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Acosta H, López SL, Revinski DR, Carrasco AE. Notch destabilises maternal β-catenin and restricts dorsal-anterior development in Xenopus. Development. 2011 June 15;138:2567-79. doi: 10.1242/dev.061143.

Notch3 signaling gates cell cycle entry and limits neural stem cell amplification in the adult pallium

Authors:
Alunni A, Krecsmarik M, Bosco A, Galant S, Pan L, Moens CB, Bally-Cuif L
Citation:
Development. 2013 Jul 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Maintaining the homeostasis of germinal zones in adult organs is a fundamental but mechanistically poorly understood process....
Organism or Cell Type:
zebrafish
Citation Extract:
Alunni A, Krecsmarik M, Bosco A, Galant S, Pan L, Moens CB, Bally-Cuif L. Notch3 signaling gates cell cycle entry and limits neural stem cell amplification in the adult pallium. Development. 2013 Jul 17. [Epub ahead of print].

Novel oligonucleotide analogues based on morpho­lino nucleoside subunits–Antisense technologies: New chemical possibilities

Authors:
Abramova TV, Kassakin MF, Silnikov VN
Citation:
Indian Journal of Chemistry Sect. B. 2009. V. 48B. p. 1721-1726.
Epub:
Not Epub
Abstract:
Even several decades after pioneer publications there is continued interest in the construction and synthesis of a variety of...
Citation Extract:
Abramova TV, Kassakin MF, Silnikov VN. Novel oligonucleotide analogues based on morpho­lino nucleoside subunits–Antisense technologies: New chemical possibilities. Indian Journal of Chemistry Sect. B. 2009. V. 48B. p. 1721-1726..

Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor

Authors:
Anant S, Henderson JO, Mukhopadhyay D, Navaratnam N, Kennedy S, Min J, Davidson NO
Citation:
J Biol Chem. 2001 Dec 14;276(50):47338-51. Epub 2001 Sep 27
Epub:
Not Epub
Abstract:
Mammalian apolipoprotein B (apoB) mRNA editing is mediated by a multicomponent holoenzyme containing apobec-1 and ACF. We have...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: rat hepatoma, McArdle7777
Citation Extract:
Anant S, Henderson JO, Mukhopadhyay D, Navaratnam N, Kennedy S, Min J, Davidson NO. Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor. J Biol Chem. 2001 Dec 14;276(50):47338-51. Epub 2001 Sep 27.

Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling

Authors:
Abu-Remaileh M, Gerson A, Farago M, Nathan G, Alkalay I, Zins Rousso S, Gur M, Fainsod A, Bergman Y
Citation:
EMBO J. 2010 Oct 6;29(19):3236-48. Epub 2010 Aug 24
Epub:
Not Epub
Abstract:
Although the transcriptional regulatory events triggered by Oct-3/4 are well documented, understanding the proteomic networks...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Abu-Remaileh M, Gerson A, Farago M, Nathan G, Alkalay I, Zins Rousso S, Gur M, Fainsod A, Bergman Y. Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling. EMBO J. 2010 Oct 6;29(19):3236-48. Epub 2010 Aug 24.

P58-A and P58-B: Novel Proteins That Mediate Skeletogenesis in the Sea Urchin Embryo

Authors:
Adomako-Ankomah A, Ettensohn CA
Citation:
Dev Biol. 2011 Feb 26. [Epub ahead of print]
Epub:
Not Epub
Abstract:
During sea urchin embryogenesis, the skeleton is produced by primary mesenchyme cells (PMCs). PMCs undergo a sequence of...
Organism or Cell Type:
sea urchin
Citation Extract:
Adomako-Ankomah A, Ettensohn CA. P58-A and P58-B: Novel Proteins That Mediate Skeletogenesis in the Sea Urchin Embryo. Dev Biol. 2011 Feb 26. [Epub ahead of print].

Peptide-based delivery of nucleic acids: design, mechanism of uptake and applications to splice-correcting oligonucleotides

Authors:
Abes S, Moulton H, Turner J, Clair P, Richard JP, Iversen P, Gait MJ, Lebleu B
Citation:
Biochem Soc Trans. 2007 Feb;35(Pt 1):53-5
Epub:
Not Epub
Abstract:
CPPs (cell-penetrating peptides) have given rise to much interest for the delivery of biomolecules such as peptides, proteins...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: HeLa AntisenseTest System
Citation Extract:
Abes S, Moulton H, Turner J, Clair P, Richard JP, Iversen P, Gait MJ, Lebleu B. Peptide-based delivery of nucleic acids: design, mechanism of uptake and applications to splice-correcting oligonucleotides. Biochem Soc Trans. 2007 Feb;35(Pt 1):53-5.

Pharmacokinetics and biodistribution of phosphorodiamidate morpholino antisense oligomers

Authors:
Amantana A, Iversen PL
Citation:
Curr Opin Pharmacol. 2005 Oct;5(5):550-5.
Epub:
Not Epub
Abstract:
The concept of using antisense oligonucleotides to interfere with gene expression offers a new therapeutic strategy for the...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Amantana A, Iversen PL. Pharmacokinetics and biodistribution of phosphorodiamidate morpholino antisense oligomers. Curr Opin Pharmacol. 2005 Oct;5(5):550-5..

Pharmacokinetics, Biodistribution, Stability and Toxicity of a Cell-Penetrating Peptide-Morpholino Oligomer Conjugate

Authors:
Amantana A, Moulton HM, Cate ML, Reddy MT, Whitehead T, Hassinger JN, Youngblood DS, Iversen PL
Citation:
Bioconjug Chem. 2007 Jul-Aug;18(4):1325-31. Epub 2007 Jun 21
Epub:
Not Epub
Abstract:
Objective: Conjugation of arginine-rich cell-penetrating peptide (CPP) to phosphorodiamidate morpholino oligomers (PMO) has...
Delivery Method:
i.v. injection, peptide conjugates vs. bare Morpholino
Organism or Cell Type:
Rat
Citation Extract:
Amantana A, Moulton HM, Cate ML, Reddy MT, Whitehead T, Hassinger JN, Youngblood DS, Iversen PL. Pharmacokinetics, Biodistribution, Stability and Toxicity of a Cell-Penetrating Peptide-Morpholino Oligomer Conjugate. Bioconjug Chem. 2007 Jul-Aug;18(4):1325-31. Epub 2007 Jun 21.

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