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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12176 scientific papers returned from the database with the search filters currently being used below.
There are 12176 scientific papers returned from the database with the search filters currently being used below.
NAMPT reduction-induced NAD+ insufficiency contributes to the compromised oocyte quality from obese mice
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Citation:
Aging Cell. 2021 Oct 18:e13496. doi: 10.1111/acel.13496. Online ahead of print Epub:
Not Epub Abstract:
Maternal obesity is associated with multiple adverse reproductive outcomes, whereas the underlying molecular mechanisms are... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Wang H, Zhu S, Wu X, Liu Y, Ge J, Wang Q, Gu L. NAMPT reduction-induced NAD+ insufficiency contributes to the compromised oocyte quality from obese mice. Aging Cell. 2021 Oct 18:e13496. doi: 10.1111/acel.13496. Online ahead of print. |
Mutated VWA8 Is Associated With Developmental Delay, Microcephaly, and Scoliosis and Plays a Novel Role in Early Development and Skeletal Morphogenesis in Zebrafish
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Citation:
Front Cell Dev Biol. 2021 Oct 1;9:736960. doi: 10.3389/fcell.2021.736960. eCollection 2021 Epub:
Not Epub Abstract:
Von Willebrand A domain-containing protein 8 (VWA8), also named KIAA0564, is a poorly characterized, mitochondrial matrix-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Umair M, Farooq Khan M, Aldrees M, Nashabat M, Alhamoudi KM, Bilal M, Alyafee Y, Al Tuwaijri A, Aldarwish M, Al-Rumayyan A, Alkhalaf H, Wadaan MAM, Alfadhel M. Mutated VWA8 Is Associated With Developmental Delay, Microcephaly, and Scoliosis and Plays a Novel Role in Early Development and Skeletal Morphogenesis in Zebrafish. Front Cell Dev Biol. 2021 Oct 1;9:736960. doi: 10.3389/fcell.2021.736960. eCollection 2021. |
Nucleolin loss of function leads to aberrant Fibroblast Growth Factor signaling and craniofacial anomalies
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Citation:
Development. 2022 Jun 15;149(12):dev200349. doi: 10.1242/dev.200349. Epub 2022 Jun 28. PMID: 35762670; PMCID: PMC9270975 Epub:
Not Epub Abstract:
Ribosomal RNA (rRNA) transcription and ribosome biogenesis are global processes required for growth and proliferation of all... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dash S, Trainor PA. Nucleolin loss of function leads to aberrant Fibroblast Growth Factor signaling and craniofacial anomalies. Development. 2022 Jun 15;149(12):dev200349. doi: 10.1242/dev.200349. Epub 2022 Jun 28. PMID: 35762670; PMCID: PMC9270975. |
The chromatin-remodeling enzyme Smarca5 regulates erythrocyte aggregation via Keap1-Nrf2 signaling
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Citation:
Elife. 2021 Oct 26;10:e72557. doi: 10.7554/eLife.72557. PMID: 34698638; PMCID: PMC8594921 Epub:
Not Epub Abstract:
Although thrombosis has been extensively studied using various animal models, our understanding of the underlying mechanism... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ding Y, Li Y, Zhao Z, Cliff Zhang Q, Liu F. The chromatin-remodeling enzyme Smarca5 regulates erythrocyte aggregation via Keap1-Nrf2 signaling. Elife. 2021 Oct 26;10:e72557. doi: 10.7554/eLife.72557. PMID: 34698638; PMCID: PMC8594921. |
Physiological Functions of Thiol Peroxidases (Gpx1 and Prdx2) during Xenopus laevis Embryonic Development
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Citation:
Antioxidants (Basel). 2021;10(10):1636. doi:10.3390/antiox10101636 Epub:
Not Epub Abstract:
Glutathione peroxidase 1 (Gpx1) and peroxiredoxin 2 (Prdx2) belong to the thiol peroxidase family of antioxidants, and have... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Lee H, Lee NY, Kim Y, Choi H-S, Ismail T, Ryu H-Y, Cho D-H, Ryoo ZY, Lee D-S, Kwon TK, Park TJ, Kwon T, Lee H-S. Physiological Functions of Thiol Peroxidases (Gpx1 and Prdx2) during Xenopus laevis Embryonic Development. Antioxidants (Basel). 2021;10(10):1636. doi:10.3390/antiox10101636. |
Progranulin A Promotes Compensatory Hepatocyte Proliferation via HGF/c-Met Signaling after Partial Hepatectomy in Zebrafish
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Citation:
Int J Mol Sci. 2021;22(20):11217. doi:10.3390/ijms222011217 Epub:
Not Epub Abstract:
Compensatory hepatocyte proliferation and other liver regenerative processes are activated to sustain normal physiological... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Chiang K-Y, Li Y-W, Li Y-H, Huang S-J, Wu C-L, Gong H-Y, Wu J-L. Progranulin A Promotes Compensatory Hepatocyte Proliferation via HGF/c-Met Signaling after Partial Hepatectomy in Zebrafish. Int J Mol Sci. 2021;22(20):11217. doi:10.3390/ijms222011217. |
A recessive variant in TFAM causes mtDNA depletion associated with primary ovarian insufficiency, seizures, intellectual disability and hearing loss
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Citation:
Hum Genet. 2021 Oct 13. doi: 10.1007/s00439-021-02380-2. Online ahead of print Epub:
Yes Abstract:
Mitochondrial disorders are collectively common, genetically heterogeneous disorders in both pediatric and adult populations.... Organism or Cell Type:
zebrafish Citation Extract: Ullah F, Rauf W, Khan K, Khan S, Bell KM, de Oliveira VC, Tariq M, Bakhshalizadeh S, Touraine P, Katsanis N, Sinclair A, He S, Tucker EJ, Baig SM, Davis EE. A recessive variant in TFAM causes mtDNA depletion associated with primary ovarian insufficiency, seizures, intellectual disability and hearing loss. Hum Genet. 2021 Oct 13. doi: 10.1007/s00439-021-02380-2. Online ahead of print. |
Antisense-Mediated Down-Regulation of Factor V-Short Splicing in a Liver Cell Line Model
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Citation:
Appl Sci. 2021;11(20):9621. doi:0.3390/app11209621 Epub:
Not Epub Abstract:
Coagulation factor V (FV) is a liver-derived protein encoded by the F5 gene. Alternative splicing of F5 exon 13 produces a low-... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HepG2 Citation Extract: Todaro AM, Hackeng TM, Castoldi E. Antisense-Mediated Down-Regulation of Factor V-Short Splicing in a Liver Cell Line Model. Appl Sci. 2021;11(20):9621. doi:0.3390/app11209621 . |
Increased locomotor activity via regulation of GABAergic signalling in foxp2 mutant zebrafish -- implications for neurodevelopmental disorders
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Citation:
Transl Psychiatry. 2021;11:529. doi:10.1038/s41398-021-01651-w Epub:
Not Epub Abstract:
Recent advances in the genetics of neurodevelopmental disorders (NDDs) have identified the transcription factor FOXP2 as one of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lüffe TM, D’Orazio A, Bauer M, Gioga Z, Schoeffler V, Lesch K-P, Romanos Ml, Drepper C, Lillesaar C. Increased locomotor activity via regulation of GABAergic signalling in foxp2 mutant zebrafish -- implications for neurodevelopmental disorders. Transl Psychiatry. 2021;11:529. doi:10.1038/s41398-021-01651-w. |
Antisense oligonucleotides: absorption, distribution, metabolism, and excretion
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Citation:
Expert Opin Drug Metab Toxicol. 2021 Oct 13. doi: 10.1080/17425255.2021.1992382. Online ahead of print Epub:
Yes Abstract:
Introduction: Antisense oligonucleotides (ASOs) have emerged as a promising novel drug modality that aims to address unmet... Citation Extract: Shadid M, Badawi M, Abulrob A. Antisense oligonucleotides: absorption, distribution, metabolism, and excretion. Expert Opin Drug Metab Toxicol. 2021 Oct 13. doi: 10.1080/17425255.2021.1992382. Online ahead of print. |