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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12176 scientific papers returned from the database with the search filters currently being used below.
There are 12176 scientific papers returned from the database with the search filters currently being used below.
A globin-family protein, cytoglobin 1, is involved in the development of neural crest-derived tissues and organs in zebrafish
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Citation:
Dev Biol. 2020 Dec 22:S0012-1606(20)30325-0. doi: 10.1016/j.ydbio.2020.12.016. Online ahead of print Epub:
Yes Abstract:
The zebrafish is an excellent model animal that is amenable to forward genetics approaches. To uncover unknown developmental... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Takahashi K, Ito Y, Yoshimura M, Nikaido M, Yuikawa T, Kawamura A, Tsuda S, Kage D, Yamasu K. A globin-family protein, cytoglobin 1, is involved in the development of neural crest-derived tissues and organs in zebrafish. Dev Biol. 2020 Dec 22:S0012-1606(20)30325-0. doi: 10.1016/j.ydbio.2020.12.016. Online ahead of print. |
CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1
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Citation:
Signal Transduct Target Ther. 2020 Dec 26;5(1):298. doi: 10.1038/s41392-020-00375-5 Epub:
Not Epub Abstract:
Sorafenib is the first-line chemotherapeutic therapy for advanced hepatocellular carcinoma (HCC). However, sorafenib resistance... Organism or Cell Type:
cell culture: HepG2-SR Citation Extract: Xu J, Ji L, Liang Y, Wan Z, Zheng W, Song X, Gorshkov K, Sun Q, Lin H, Zheng X, Chen J, Jin RA, Liang X, Cai X. CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1. Signal Transduct Target Ther. 2020 Dec 26;5(1):298. doi: 10.1038/s41392-020-00375-5. |
Mutation in epsilon-Sarcoglycan Induces a Myoclonus-Dystonia Syndrome-Like Movement Disorder in Mice
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Citation:
Neurosci Bull. 2020 Dec 23. doi: 10.1007/s12264-020-00612-5. Online ahead of print Epub:
Not Epub Abstract:
Myoclonus dystonia syndrome (MDS) is an inherited movement disorder, and most MDS-related mutations have so far been found in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li J, Liu Y, Li Q, Huang X, Zhou D, Xu H, Zhao F, Mi X, Wang R, Jia F, Xu F, Yang J, Liu D, Deng X, Zhang Y. Mutation in epsilon-Sarcoglycan Induces a Myoclonus-Dystonia Syndrome-Like Movement Disorder in Mice. Neurosci Bull. 2020 Dec 23. doi: 10.1007/s12264-020-00612-5. Online ahead of print. |
Discovery and Mechanistic Characterization of a Select Modulator of AhR-regulated Transcription (SMAhRT) with Anti-cancer Effects
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Citation:
Apoptosis. 2021 Jun;26(5-6):307-322. doi: 10.1007/s10495-021-01666-0. Epub 2021 Apr 24. PMID: 33893898 Epub:
Not Epub Abstract:
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor and a member of the bHLH/PAS (basic Helix-Loop-... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: Hepa 1 Citation Extract: O'Donnell EF 3rd, Jang HS, Liefwalker DF, Kerkvliet NI, Kolluri SK. Discovery and Mechanistic Characterization of a Select Modulator of AhR-regulated Transcription (SMAhRT) with Anti-cancer Effects. Apoptosis. 2021 Jun;26(5-6):307-322. doi: 10.1007/s10495-021-01666-0. Epub 2021 Apr 24. PMID: 33893898. |
Phosphorylation of seryl-tRNA synthetase by ATM/ATR is essential for hypoxia-induced angiogenesis
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Citation:
PLoS Biol. 2020;18(12):e3000991. doi:10.1371/journal.pbio.3000991 Epub:
Not Epub Abstract:
Hypoxia-induced angiogenesis maintains tissue oxygen supply and protects against ischemia but also enhances tumor progression... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shi Y, Liu Z, Zhang Q, Vallee I, Mo Z, Kishi S, Yang X-L. Phosphorylation of seryl-tRNA synthetase by ATM/ATR is essential for hypoxia-induced angiogenesis. PLoS Biol. 2020;18(12):e3000991. doi:10.1371/journal.pbio.3000991. |
Nrl is dispensable for specification of rod photoreceptors in adult zebrafish contrasting a deeply conserved requirement earlier in ontogeny
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Citation:
iScience. 2020;23(12):101805 doi:10.1016/j.isci.2020.101805 Epub:
Not Epub Abstract:
The transcription factor NRL (neural retina leucine zipper) has been canonized as the master regulator of photoreceptor cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Oel AP, Neil GJ, Dong EM, Balay SD, Collett K, Allison WT. Nrl is dispensable for specification of rod photoreceptors in adult zebrafish contrasting a deeply conserved requirement earlier in ontogeny. iScience. 2020;23(12):101805 doi:10.1016/j.isci.2020.101805. |
Post-transcriptional tuning of FGF signaling mediates neural crest induction
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Citation:
Proc Nat Acad Sci USA. 2020;[Epub ahead of print] doi:10.1073/pnas.2009997117 Epub:
Not Epub Abstract:
Ectodermal patterning is required for the establishment of multiple components of the vertebrate body plan. Previous studies... Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Copeland J, Simoes-Costa M. Post-transcriptional tuning of FGF signaling mediates neural crest induction. Proc Nat Acad Sci USA. 2020;[Epub ahead of print] doi:10.1073/pnas.2009997117. |
The Genome-Wide Impact of Nipblb Loss-of-Function on Zebrafish Gene Expression
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Citation:
Int J Mol Sci. 2020 Dec 19;21(24):E9719. doi: 10.3390/ijms21249719 Epub:
Not Epub Abstract:
Transcriptional changes normally occur during development but also underlie differences between healthy and pathological... Organism or Cell Type:
zebrafish Citation Extract: Spreafico M, Mangano E, Mazzola M, Consolandi C, Bordoni R, Battaglia C, Bicciato S, Marozzi A, Pistocchi A. The Genome-Wide Impact of Nipblb Loss-of-Function on Zebrafish Gene Expression. Int J Mol Sci. 2020 Dec 19;21(24):E9719. doi: 10.3390/ijms21249719. |
MOTS‐c promotes phosphorodiamidate morpholino oligomer uptake and efficacy in dystrophic mice
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Citation:
EMBO Mol Med. 2020;13:e12993 doi:10.15252/emmm.202012993 Epub:
Not Epub Abstract:
Antisense oligonucleotide (AO)‐mediated exon‐skipping therapies show promise in Duchenne muscular dystrophy (DMD), a... Delivery Method:
unlinked MOTS‐c peptide Organism or Cell Type:
mouse mdx Citation Extract: Ran N, Lin C, Leng L, Han G, Geng M, Wu Y, Bittner S, Moulton H, Yin H. MOTS‐c promotes phosphorodiamidate morpholino oligomer uptake and efficacy in dystrophic mice. EMBO Mol Med. 2020;13:e12993 doi:10.15252/emmm.202012993. |
Dpysl2 (CRMP2) is required for the migration of facial branchiomotor neurons in the developing zebrafish embryo
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Citation:
Int J Dev Biol. 2020;64(10-11-12):479-484. doi: 10.1387/ijdb.190375to Epub:
Not Epub Abstract:
Dihydropyrimidinase-like family proteins (Dpysls) are relevant in several processes during nervous system development; among... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fiallos-Oliveros C, Ohshima T. Dpysl2 (CRMP2) is required for the migration of facial branchiomotor neurons in the developing zebrafish embryo. Int J Dev Biol. 2020;64(10-11-12):479-484. doi: 10.1387/ijdb.190375to. |