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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

The investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish

Authors:
Kim HR, Santhakumar K, Markham E, Baldera D, Bryant HE, El-Khamisy SF, van Eeden FJM
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/767459
Epub:
Not Epub
Abstract:
pVHL is a tumor suppressor. The lack of its function leads to various tumors, among which ccRCC (clear cell renal cell...
Link:
https://www.biorxiv.org/content/10.1101/767459v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim HR, Santhakumar K, Markham E, Baldera D, Bryant HE, El-Khamisy SF, van Eeden FJM. The investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish. bioRxiv. 2019;[preprint] doi:10.1101/767459.

Rgma-induced Neo1 proteolysis promotes neural tube morphogenesis

Authors:
Brown S, Jayachandran P, Negesse M, Olmo V, Vital E, Brewster R
Citation:
J Neurosci. 2019 Aug 9. pii: 3262-18. doi: 10.1523/JNEUROSCI.3262-18.2019. [Epub ahead of print]
Epub:
Yes
Abstract:
Neuroepithelial cell (NEC) elongation is one of several key cell behaviors that mediate the tissue-level morphogenetic...
Link:
https://www.jneurosci.org/content/39/38/7465
Organism or Cell Type:
zebrafish
Citation Extract:
Brown S, Jayachandran P, Negesse M, Olmo V, Vital E, Brewster R. Rgma-induced Neo1 proteolysis promotes neural tube morphogenesis. J Neurosci. 2019 Aug 9. pii: 3262-18. doi: 10.1523/JNEUROSCI.3262-18.2019. [Epub ahead of print].

The evolution of a new cell type was associated with competition for a signaling ligand

Authors:
Ettensohn CA, Adomako-Ankomah A
Citation:
PLoS Biol. 2019;17(9):e3000460. doi:10.1371/journal.pbio.3000460
Epub:
Not Epub
Abstract:
There is presently a very limited understanding of the mechanisms that underlie the evolution of new cell types. The skeleton-...
Link:
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000460
Delivery Method:
microinjection
Organism or Cell Type:
Lytechinus variegatus (sea urchin)
Citation Extract:
Ettensohn CA, Adomako-Ankomah A. The evolution of a new cell type was associated with competition for a signaling ligand. PLoS Biol. 2019;17(9):e3000460. doi:10.1371/journal.pbio.3000460.

BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers

Authors:
Kuznetsov JN, Aguero TH, Owens DA, Kurtenbach S, Field MG, Durante MA
Citation:
Sci Adv. 2019;5(9):eaax1734. doi:10.1126/sciadv.aax1738
Epub:
Not Epub
Abstract:
The BAP1 tumor suppressor is mutated in many human cancers such as uveal melanoma, leading to poor patient outcome. It remains...
Link:
https://advances.sciencemag.org/content/5/9/eaax1738
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kuznetsov JN, Aguero TH, Owens DA, Kurtenbach S, Field MG, Durante MA. BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers. Sci Adv. 2019;5(9):eaax1734. doi:10.1126/sciadv.aax1738.

TEADs, Yap, Taz, Vgll4s transcription factors control the establishment of Left-Right asymmetry in Zebrafish

Authors:
Fillatre J, Fauny JD, Fels JA, Li C, Goll M, Thisse C, Thisse B
Citation:
Elife. 2019 Sep 12;8. pii: e45241. doi: 10.7554/eLife.45241. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In many vertebrates, establishment of Left-Right (LR) asymmetry results from the activity of a ciliated organ functioning as...
Link:
https://elifesciences.org/articles/45241
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fillatre J, Fauny JD, Fels JA, Li C, Goll M, Thisse C, Thisse B. TEADs, Yap, Taz, Vgll4s transcription factors control the establishment of Left-Right asymmetry in Zebrafish. Elife. 2019 Sep 12;8. pii: e45241. doi: 10.7554/eLife.45241. [Epub ahead of print].

miR-301a Regulates Inflammatory Response to Japanese Encephalitis Virus Infection via Suppression of NKRF Activity

Authors:
Hazra B, Chakraborty S, Bhaskar M, Mukherjee S, Mahadevan A, Basu A
Citation:
J Immunol. 2019 Oct 15;203(8):2222-2238. doi: 10.4049/jimmunol.1900003. Epub 2019 Sep 16. PMID: 31527198.
Epub:
Yes
Abstract:
Microglia being the resident macrophage of brain provides neuroprotection following diverse microbial infections. Japanese...
Link:
https://journals.aai.org/jimmunol/article/203/8/2222/107604/miR-301a-Regulates-Inflammatory-Response-to
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Hazra B, Chakraborty S, Bhaskar M, Mukherjee S, Mahadevan A, Basu A. miR-301a Regulates Inflammatory Response to Japanese Encephalitis Virus Infection via Suppression of NKRF Activity. J Immunol. 2019 Oct 15;203(8):2222-2238. doi: 10.4049/jimmunol.1900003. Epub 2019 Sep 16. PMID: 31527198..

ECM alterations in Fndc3a (Fibronectin Domain Containing Protein 3A) deficient zebrafish cause temporal fin development and regeneration defects

Authors:
Liedtke D, Orth M, Meissler M, Geuer S, Knaup S, Köblitz I, Klopocki E
Citation:
Sci Rep. 2019;9(1):13383. doi:10.1038/s41598-019-50055-w
Epub:
Not Epub
Abstract:
Fin development and regeneration are complex biological processes that are highly relevant in teleost fish. They share genetic...
Link:
https://www.nature.com/articles/s41598-019-50055-w
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liedtke D, Orth M, Meissler M, Geuer S, Knaup S, Köblitz I, Klopocki E. ECM alterations in Fndc3a (Fibronectin Domain Containing Protein 3A) deficient zebrafish cause temporal fin development and regeneration defects. Sci Rep. 2019;9(1):13383. doi:10.1038/s41598-019-50055-w.

Identification of ATP synthase α subunit as a new maternal factor capable of protecting zebrafish embryos from bacterial infection

Authors:
Ni S, Zhou Y, Chen Y, Du X, Zhang S
Citation:
FASEB J. 2019 Sep 13:fj201901290R. doi: 10.1096/fj.201901290R. [Epub ahead of print]
Epub:
Yes
Abstract:
Previous studies have shown that ATP synthase α subunit (ATP5A1) plays multiple roles, but our understanding of its biologic...
Link:
https://www.fasebj.org/doi/abs/10.1096/fj.201901290R
Organism or Cell Type:
zebrafish
Citation Extract:
Ni S, Zhou Y, Chen Y, Du X, Zhang S. Identification of ATP synthase α subunit as a new maternal factor capable of protecting zebrafish embryos from bacterial infection. FASEB J. 2019 Sep 13:fj201901290R. doi: 10.1096/fj.201901290R. [Epub ahead of print].

Downregulation of hepatic stem cell factor by Vivo-Morpholino treatment inhibits mast cell migration and decreases biliary damage/senescence and liver fibrosis in Mdr2−/− mice

Authors:
Vik Meadows V, Kennedy L, Hargrove L, Demieville J, Meng F, Virani S, Reinhart E, Kyritsi K, Invernizzi P, Yang Z, Wu N, Liangpunsakul S, Alpini G, Francis H
Citation:
Biochem Biophys Acta. 2019;[Epub ahead of print] doi:10.1016/j.bbadis.2019.165557
Epub:
Yes
Abstract:
Abstract: Primary sclerosing cholangitis (PSC) is characterized by increased mast cell (MC) infiltration, biliary damage and...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0925443919302807
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Vik Meadows V, Kennedy L, Hargrove L, Demieville J, Meng F, Virani S, Reinhart E, Kyritsi K, Invernizzi P, Yang Z, Wu N, Liangpunsakul S, Alpini G, Francis H. Downregulation of hepatic stem cell factor by Vivo-Morpholino treatment inhibits mast cell migration and decreases biliary damage/senescence and liver fibrosis in Mdr2−/− mice. Biochem Biophys Acta. 2019;[Epub ahead of print] doi:10.1016/j.bbadis.2019.165557.

A Complex of U1 snRNP with Cleavage and Polyadenylation Factors Controls Telescripting, Regulating mRNA Transcription in Human Cells

Authors:
So BR, Di C, Cai Z, Oh J-M, Arai C, Dreyfuss G
Citation:
Molec Cell. 2019;[Epub ahead of print] doi:10.1016/j.molcel.2019.08.007
Epub:
Yes
Abstract:
Full-length transcription in the majority of human genes depends on U1 snRNP (U1) to co-transcriptionally suppress...
Link:
https://www.cell.com/molecular-cell/fulltext/S1097-2765(19)30623-9
Citation Extract:
So BR, Di C, Cai Z, Oh J-M, Arai C, Dreyfuss G. A Complex of U1 snRNP with Cleavage and Polyadenylation Factors Controls Telescripting, Regulating mRNA Transcription in Human Cells. Molec Cell. 2019;[Epub ahead of print] doi:10.1016/j.molcel.2019.08.007.

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