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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis
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Citation:
Dev Dyn. 2019 Apr 13. doi: 10.1002/dvdy.39. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: Kabuki syndrome is a haploinsufficient congenital multi-organ malformation syndrome, which frequently includes... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Schwenty-Lara J, Nürnberger A, Borchers A. Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis. Dev Dyn. 2019 Apr 13. doi: 10.1002/dvdy.39. [Epub ahead of print]. |
The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/583807 Epub:
Not Epub Abstract:
Understanding how complex organ systems are assembled from simple embryonic tissues is a major challenge. Across the animal... Delivery Method:
Endo-Porter PEG Organism or Cell Type:
cell culture: Gallus gallus (chick) somite tissue Citation Extract: Grocott T, Lozano-Velasco E, Mok GF, Münsterberg AE. The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network. bioRxiv. 2019;[preprint] doi:10.1101/583807. |
Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/570820 Epub:
Not Epub Abstract:
Coordinated migration of cell collectives is important during embryonic development and relies on cells integrating multiple... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wei L, Blader P, Roussigné M. Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration. bioRxiv. 2019;[preprint] doi:10.1101/570820. |
Developmentally regulated tcf7l2 splice variants mediate transcriptional repressor functions during eye formation
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/607713 Epub:
Not Epub Abstract:
Tcf7l2 mediates Wnt/β-Catenin signalling during development and is implicated in cancer and type-2 diabetes. The mechanisms by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Young RM, Ewan KB, Ferrer VP, Allende ML, Dale TC, Wilson SW. Developmentally regulated tcf7l2 splice variants mediate transcriptional repressor functions during eye formation. bioRxiv. 2019;[preprint] doi:10.1101/607713 . |
miR‐181a/b downregulation exerts a protective action on mitochondrial disease models
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Citation:
EMBO Molec Med. 2019;e8734 [Epub ahead of print] doi:10.15252/emmm.201708734 Epub:
Yes Abstract:
Mitochondrial diseases (MDs) are a heterogeneous group of devastating and often fatal disorders due to defective oxidative... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Indrieri A, Carrella S, Romano A, Spaziano A, Marrocco E, Fernandez‐Vizarra E, Barbato S, Pizzo M, Ezhova Y, Golia FM, Ciampi L, Tammaro R, Henao‐Mejia J, Williams A, Flavell RA, De Leonibus E, Zeviani M, Surace EM, Banfi S, Franco B. miR‐181a/b downregulation exerts a protective action on mitochondrial disease models. EMBO Molec Med. 2019;e8734 [Epub ahead of print] doi:10.15252/emmm.201708734. |
In Ovo Electroporation of Plasmid DNA and Morpholinos into Specific Tissues During Early Embryogenesis
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Citation:
Neural Crest Cells. 2019. Methods in Molecular Biology (1976):71-82 Springer New York, New York, NY. doi:10.1007/978-1-4939-9412-0_6 Epub:
Not Epub Abstract:
In ovo electroporation enables transfection of non-viral plasmid DNA and/or morpholinos to fluorescently label and/or perturb... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: McLennan R, Kulesa PM. In Ovo Electroporation of Plasmid DNA and Morpholinos into Specific Tissues During Early Embryogenesis. Neural Crest Cells. 2019. Methods in Molecular Biology (1976):71-82 Springer New York, New York, NY. doi:10.1007/978-1-4939-9412-0_6. |
Neutrophils use selective autophagy receptor p62 to target Staphylococcus aureus for degradation in the zebrafish model
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/604884 Epub:
Not Epub Abstract:
Autophagy leads to degradation of cellular components, and has an important role in destroying intracellular pathogens.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gibson JF, Prajsnar TK, Serba JJ, Tonge RD, Grierson AJ, Ingham PW, Renshaw SA, Johnston SA
. Neutrophils use selective autophagy receptor p62 to target Staphylococcus aureus for degradation in the zebrafish model. bioRxiv. 2019;[preprint] doi:10.1101/604884 . |
Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation
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Citation:
iScience. 2019;[Epub ahead of print] doi:10.1016/j.isci.2019.04.007 Epub:
Yes Abstract:
Thalidomide is a teratogen that causes multiple malformations in the developing baby through its interaction with Cereblon (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ando H, Sato T, Ito T, Yamamoto J, Sakamoto S, Nitta N, Asatsuma-Okumura T, Shimizu N, Mizushima R, Aoki I, Imai T, Yamaguchi Y, Berk AJ, Handa H
. Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation. iScience. 2019;[Epub ahead of print] doi:10.1016/j.isci.2019.04.007. |
A High-Throughput Assay for Congenital and Age-Related Eye Diseases in Zebrafish
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Citation:
Biomedicines. 2019;7(2):28 doi:10.3390/biomedicines7020028 Epub:
Not Epub Abstract:
Debilitating visual impairment caused by cataracts or microphthalmia is estimated to affect roughly 20 million people in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Brastrom LK, Scott CA, Dawson DV, Slusarski DC. A High-Throughput Assay for Congenital and Age-Related Eye Diseases in Zebrafish. Biomedicines. 2019;7(2):28 doi:10.3390/biomedicines7020028. |
ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer
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Citation:
Brit J Cancer. 2019;[Epub ahead of print] doi:doi.org/10.1038/s41416-019-0448-z Epub:
Yes Abstract:
Background: Triple-negative breast cancers (TNBC) are poor-prognosis tumours candidate to chemotherapy as only systemic... Organism or Cell Type:
Xenopus Citation Extract: Daulat AM, Finetti P, Revinski D, Wagner MS, Camoin L, Audebert S, Birnbaum D, Kodjabachian L, Borg J-P, Bertucci F. ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer. Brit J Cancer. 2019;[Epub ahead of print] doi:doi.org/10.1038/s41416-019-0448-z. |