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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
HSP60 critically regulates endogenous IL-1β production in activated microglia by stimulating NLRP3 inflammasome pathway
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Citation:
J Neuroinflammation. 2018 Jun 9;15(1):177. doi: 10.1186/s12974-018-1214-5 Epub:
Not Epub Abstract:
BACKGROUND: Interleukin-1β (IL-1β) is one of the most important cytokine secreted by activated microglia as it orchestrates the... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
BALB/c mice Citation Extract: Swaroop S, Mahadevan A, Shankar SK, Adlakha YK, Basu A. HSP60 critically regulates endogenous IL-1β production in activated microglia by stimulating NLRP3 inflammasome pathway. J Neuroinflammation. 2018 Jun 9;15(1):177. doi: 10.1186/s12974-018-1214-5. |
Macrophages protect Talaromyces marneffei conidia from myeloperoxidase-dependent neutrophil fungicidal activity during infection establishment in vivo
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Citation:
PLoS Pathog. 2018 Jun 8;14(6):e1007063. doi: 10.1371/journal.ppat.1007063. [Epub ahead of print] Epub:
Not Epub Abstract:
Neutrophils and macrophages provide the first line of cellular defence against pathogens once physical barriers are breached,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ellett F, Pazhakh V, Pase L, Benard EL, Weerasinghe H, Azabdaftari D, Alasmari S, Andrianopoulos A, Lieschke GJ. Macrophages protect Talaromyces marneffei conidia from myeloperoxidase-dependent neutrophil fungicidal activity during infection establishment in vivo. PLoS Pathog. 2018 Jun 8;14(6):e1007063. doi: 10.1371/journal.ppat.1007063. [Epub ahead of print]. |
Integrating glycomics and genomics uncovers SLC10A7 as essential factor for bone mineralization by regulating post-Golgi protein transport and glycosylation
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Citation:
Hum Mol Genet. 2018 Jun 5. doi: 10.1093/hmg/ddy213. [Epub ahead of print] Epub:
Yes Abstract:
Genomics methodologies have significantly improved elucidation of Mendelian disorders. The combination with high-throughput... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ashikov A, Abu Bakar N, Wen XY, Niemeijer M, Rodrigues Pinto Osorio G, Brand-Arzamendi K, Hasadsri L, Hansikova H, Raymond K, Vicogne D, Simon MEH, Pfundt R, Timal S, Beumers R, Biot C, Smeets R, Kersten M, Huijben K; CDG group , Ta Linders P, van den Bogaart G, van Hijum SAFT, Rodenburg R, van den Heuvel LP, van Spronsen F, Honzik T, Foulquier F, van Scherpenzeel M, Lefeber DJ. Integrating glycomics and genomics uncovers SLC10A7 as essential factor for bone mineralization by regulating post-Golgi protein transport and glycosylation. Hum Mol Genet. 2018 Jun 5. doi: 10.1093/hmg/ddy213. [Epub ahead of print]. |
BMP and FGF signaling interact to pattern mesoderm by controlling basic helix-loop-helix transcription factor activity
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Citation:
eLife. 2018;7:e31018. doi:10.7554/eLife.31018 Epub:
Not Epub Abstract:
The mesodermal germ layer is patterned into mediolateral subtypes by signaling factors including BMP and FGF. How these... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Row RH, Pegg A, Kinney B, Farr GH, Maves L, Lowell S, Wilson V, Martin BL. BMP and FGF signaling interact to pattern mesoderm by controlling basic helix-loop-helix transcription factor activity. eLife. 2018;7:e31018. doi:10.7554/eLife.31018. |
Blocking the 5′ splice site of exon 4 by a morpholino oligomer triggers APOL1 protein isoform switch
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Citation:
Sci Rep. 2018;8:8739 doi:10.1038/s41598-018-27104-x Epub:
Not Epub Abstract:
APOL1 risk alleles G1 or G2 are associated with a kidney disease phenotype exclusively in people of recent African ancestry.... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: AB8/13 podocytes Citation Extract: Cheatham AM, Davis SE, Khatua AK, Popik W. Blocking the 5′ splice site of exon 4 by a morpholino oligomer triggers APOL1 protein isoform switch. Sci Rep. 2018;8:8739 doi:10.1038/s41598-018-27104-x. |
Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy
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Citation:
Sci Transl Med. 2018;10(444):eaat0195. doi:10.1126/scitranslmed.aat0195 Epub:
Not Epub Abstract:
Exosomes are circulating nanovesicular carriers of macromolecules, increasingly used for diagnostics and therapeutics. The... Delivery Method:
exosome Organism or Cell Type:
mice Citation Extract: Gao X, Ran N, Dong X, Zuo B, Yang R, Zhuo Q, Hong M. Moulton HM, Seow Y, Yin HF. Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy. Sci Transl Med. 2018;10(444):eaat0195. doi:10.1126/scitranslmed.aat0195. |
Spatio-temporal regulation of concurrent developmental processes by generic signaling downstream of chemokine receptors
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Citation:
eLife. 2018;7:e33574. doi:10.7554/eLife.33574 Epub:
Not Epub Abstract:
Chemokines are secreted proteins that regulate a range of processes in eukaryotic organisms. Interestingly, different chemokine... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Malhotra D, Shin J, Solnica-Krezel L, Raz E. Spatio-temporal regulation of concurrent developmental processes by generic signaling downstream of chemokine receptors. eLife. 2018;7:e33574. doi:10.7554/eLife.33574. |
Functional roles of the Ripply-mediated suppression of segmentation gene expression at the anterior presomitic mesoderm in zebrafish
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Citation:
Mech Dev. 2018;[Epub ahead of print] doi:10.1016/j.mod.2018.06.001 Epub:
Yes Abstract:
Somites sequentially form with a regular interval by the segmentation from the anterior region of the presomitic mesoderm (PSM... Organism or Cell Type:
zebrafish Citation Extract: Kinoshita H, Ohgane N, Fujino Y, Yabe T, Hiroki Ovara H, Yokota D, Izuka A, Kage D, Yamasu K, Takada S, Kawamura A. Functional roles of the Ripply-mediated suppression of segmentation gene expression at the anterior presomitic mesoderm in zebrafish. Mech Dev. 2018;[Epub ahead of print] doi:10.1016/j.mod.2018.06.001. |
PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis
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Citation:
eLife. 2018;7:e33800 doi: 10.7554/eLife.33800 Epub:
Not Epub Abstract:
Alveolar rhabdomyosarcoma is a pediatric soft-tissue sarcoma caused by PAX3/7-FOXO1 fusion oncogenes and is characterized by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kendall GC, Watson S, Xu L, LaVigne CA, Murchison W, Rakheja D, Skapek SX, Tirode F, Delattre O, Amatruda JF. PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis. eLife. 2018;7:e33800 doi: 10.7554/eLife.33800. |
The homeobox protein VentX reverts immune suppression in the tumor microenvironment
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Citation:
Nat Comm. 2018;9:2175. doi:10.1038/s41467-018-04567-0 Epub:
Not Epub Abstract:
Immune suppression in the tumor microenvironment (TME) is a central obstacle to effective immunotherapy. Tumor-associated... Delivery Method:
electroporation Organism or Cell Type:
cell culture: human tumor associated macrophages (TAM) or human primary monocytes Citation Extract: Le Y, Gao H, Bleday R, Zhu Z. The homeobox protein VentX reverts immune suppression in the tumor microenvironment. Nat Comm. 2018;9:2175. doi:10.1038/s41467-018-04567-0. |